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Chemistry

D-Index
44
Citations
5796
World Ranking
17001
National Ranking
4186

Overview

Jean M. Bidlack is affiliated with the University of Rochester in the United States. Their research primarily spans biochemistry, genetics, molecular biology, neuroscience, and medicine. The focus includes molecular biology, cellular and molecular neuroscience, neurology, infectious diseases, and physiology.

Their work covers several key research topics:

  • Neuropeptides and animal physiology
  • Receptor mechanisms and signaling
  • Pharmacological receptor mechanisms and effects
  • Long-term effects of COVID-19
  • Neurotransmitter receptor influence on behavior
  • Fibroblast growth factor research
  • Epigenetics and DNA methylation

Jean M. Bidlack has contributed to publications in numerous venues, with frequent appearances in:

  • NeuroImmune Pharmacology and Therapeutics
  • Journal of Neuroimmune Pharmacology
  • Molecular Pharmacology
  • International Journal of Molecular Sciences
  • Neuropharmacology

Recent papers authored or coauthored by Bidlack include the following:

  • "Unique Pharmacological Properties of the Kappa Opioid Receptor Signaling Through Gαz as Shown with Bioluminescence Resonance Energy Transfer" (2020), published in Molecular Pharmacology
  • "The Delta-Specific Opioid Glycopeptide BBI-11008: CNS Penetration and Behavioral Analysis in a Preclinical Model of Levodopa-Induced Dyskinesia" (2020), published in International Journal of Molecular Sciences
  • "Mice with high FGF21 serum levels had a reduced preference for morphine and an attenuated development of acute antinociceptive tolerance and physical dependence" (2021), published in Neuropharmacology
  • "Behavioral pharmacology of the mixed-action delta-selective opioid receptor agonist BBI-11008: studies on acute, inflammatory and neuropathic pain, respiration, and drug self-administration" (2020), published in Psychopharmacology
  • "Mu Opioid Receptor Positive Allosteric Modulator BMS-986122 Confers Agonist-Dependent G Protein Subtype Signaling Bias" (2025), published in Biochemistry

Jean M. Bidlack collaborates frequently with several researchers, such as:

  • Sulie L. Chang
  • Brian I. Knapp
  • Sanjay B. Maggirwar
  • Santosh Kumar
  • Sowmya V. Yelamanchili

Best Publications

  • Differential Targeting of Gßγ-Subunit Signaling with Small Molecules

    Tabetha M. Bonacci;Jennifer L. Mathews;Chujun Yuan;David M. Lehmann

  • Evidence for opioid receptors on cells involved in host defense and the immune system.

    Burt M Sharp;Sabita Roy;Jean M Bidlack

  • Detection and Function of Opioid Receptors on Cells from the Immune System

    Jean M. Bidlack

  • An all D-amino acid opioid peptide with central analgesic activity from a combinatorial library

    CT Dooley;NN Chung;BC Wilkes;PW Schiller

  • kappa opioid receptors in human microglia downregulate human immunodeficiency virus 1 expression.

    Chun C. Chao;Genya Gekker;Shuxian Hu;Wen S. Sheng

  • Nalmefene induced elevation in serum prolactin in normal human volunteers: partial kappa opioid agonist activity?

    Gavin Bart;James H Schluger;Lisa Borg;Ann Ho

  • Purification of the opiate receptor from rat brain.

    Jean M. Bidlack;Leo G. Abood;Peter Osei-Gyimah;Sydney Archer

  • Selective Ligands for the μ, δ, and κ Opioid Receptors Identified from a Single Mixture Based Tetrapeptide Positional Scanning Combinatorial Library

    Colette T. Dooley;Phibun Ny;Jean M. Bidlack;Richard A. Houghten

  • Design and synthesis of novel dimeric morphinan ligands for kappa and micro opioid receptors.

    John L. Neumeyer;Ao Zhang;Wennan Xiong;Xiao-Hui Gu

  • Stereospecific 3H-nicotine binding to intact and solubilized rat brain membranes and evidence for its noncholinergic nature

    L.G. Abood;D.T. Reynolds;J.M. Bidlack

  • Sites and mechanisms for nicotine's action in the brain.

    L.G. Abood;D.T. Reynolds;H. Booth;J.M. Bidlack

  • Opioid receptors and signaling on cells from the immune system.

    Jean M. Bidlack;Maxim Khimich;Amy L. Parkhill;Sarah Sumagin

  • Syntheses of novel high affinity ligands for opioid receptors.

    Mark P. Wentland;Rongliang Lou;Qun Lu;Yigong Bu

  • A Novel Gβγ-Subunit Inhibitor Selectively Modulates μ-Opioid-Dependent Antinociception and Attenuates Acute Morphine-Induced Antinociceptive Tolerance and Dependence

    Jennifer L. Mathews;Alan V. Smrcka;Jean M. Bidlack

  • Purification, Cloning, and Tissue Distribution of a 23-kDa Rat Protein Isolated by Morphine Affinity Chromatography

    David K. Grandy;Eric Hanneman;James Bunzow;Marjorie Shih

  • 8-Carboxamidocyclazocine analogues: redefining the structure-activity relationships of 2,6-methano-3-benzazocines.

    Mark P. Wentland;Rongliang Lou;Yingchun Ye;Dana J. Cohen

  • In Vivo Characterization of MMP-2200, a Mixed δ/μ Opioid Agonist, in Mice

    John J. Lowery;Tyler J. Raymond;Denise Giuvelis;Jean M. Bidlack

  • Solubilization of the opiate receptor.

    J.M. Bidlack;L.G. Abood

  • Synthesis and opioid receptor affinity of morphinan and benzomorphan derivatives: mixed kappa agonists and mu agonists/antagonists as potential pharmacotherapeutics for cocaine dependence.

    John L. Neumeyer;Jean M. Bidlack;Rushi Zong;Venkatesalu Bakthavachalam

  • κ-Opioid binding sites on a murine lymphoma cell line

    Jean M. Bidlack;Lalitha D. Saripalli;Diane M.P. Lawrence

  • 2-aminothiazole-derived opioids. Bioisosteric replacement of phenols.

    Ao Zhang;Wennan Xiong;James E. Hilbert;Emily K. Devita

  • Pharmacological Properties of Bivalent Ligands Containing Butorphan Linked to Nalbuphine, Naltrexone, and Naloxone at μ, δ, and κ Opioid Receptors

    Xuemei Peng;Brian I. Knapp;Jean M. Bidlack;John L. Neumeyer

Frequent Co-Authors

John L. Neumeyer
John L. Neumeyer Harvard University
Nancy K. Mello
Nancy K. Mello Harvard University
Paul R. Albert
Paul R. Albert Ottawa Hospital
Olivier Civelli
Olivier Civelli University of California, Irvine
Alan V. Smrcka
Alan V. Smrcka University of Michigan–Ann Arbor
Stanley D. Glick
Stanley D. Glick Albany Medical Center Hospital
Richard A. Houghten
Richard A. Houghten Florida International University
Ania K. Majewska
Ania K. Majewska University of Rochester
Severo Salvadori
Severo Salvadori University of Ferrara

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