D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 61 Citations 9,156 115 World Ranking 1650 National Ranking 820

Overview

What is he best known for?

The fields of study he is best known for:

  • Cytokine
  • Immune system
  • Virus

Shuxian Hu mostly deals with Microglia, Immunology, Tumor necrosis factor alpha, Cytokine and Interleukin. His Microglia study combines topics in areas such as Central nervous system, Neuroglia, Neuroinflammation, Cell biology and Macrophage. He combines subjects such as Astrocyte and Pharmacology with his study of Neuroglia.

His Immunology study frequently draws parallels with other fields, such as Neurodegeneration. His work deals with themes such as Molecular biology and Cancer research, which intersect with Tumor necrosis factor alpha. His Cytokine study incorporates themes from Peripheral blood mononuclear cell, Stem cell and Opioid.

His most cited work include:

  • Role of Microglia in Central Nervous System Infections (500 citations)
  • Cytokine Effects on Glutamate Uptake by Human Astrocytes (277 citations)
  • Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism. (245 citations)

What are the main themes of his work throughout his whole career to date?

Shuxian Hu focuses on Microglia, Immunology, Cytokine, Chemokine and Tumor necrosis factor alpha. His Microglia research incorporates themes from Neuroglia, Receptor, Molecular biology, Cell biology and Pharmacology. His work on Immunology is being expanded to include thematically relevant topics such as Central nervous system.

His research integrates issues of Interferon and Endocrinology in his study of Cytokine. His Chemokine research is multidisciplinary, relying on both Herpes simplex virus and Virology. His Tumor necrosis factor alpha study which covers Lipopolysaccharide that intersects with -Naloxone.

He most often published in these fields:

  • Microglia (58.55%)
  • Immunology (55.26%)
  • Cytokine (30.92%)

What were the highlights of his more recent work (between 2011-2021)?

  • Immunology (55.26%)
  • Neuroinflammation (12.50%)
  • CD8 (9.21%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Immunology, Neuroinflammation, CD8, Microglia and Immune system. His work on Chemokine as part of general Immunology study is frequently connected to Cellular differentiation, therefore bridging the gap between diverse disciplines of science and establishing a new relationship between them. His Chemokine study combines topics from a wide range of disciplines, such as Proinflammatory cytokine and TLR2.

His biological study spans a wide range of topics, including Regulatory T cell and Interferon gamma. His Microglia research includes elements of Interleukin, Cannabinoid receptor type 2, Astrocyte and Pharmacology. His Immune system study integrates concerns from other disciplines, such as Virus and Stimulation.

Between 2011 and 2021, his most popular works were:

  • Reactive Oxygen Species from Human Astrocytes Induced Functional Impairment and Oxidative Damage (49 citations)
  • Modulation of Experimental Herpes Encephalitis-Associated Neurotoxicity through Sulforaphane Treatment (41 citations)
  • Glial cells suppress postencephalitic CD8+ T lymphocytes through PD-L1. (35 citations)

In his most recent research, the most cited papers focused on:

  • Immune system
  • Cytokine
  • Virus

Immunology, Neuroinflammation, CD8, Immune system and T cell are his primary areas of study. Specifically, his work in Immunology is concerned with the study of Microglia. In his study, Interleukin is strongly linked to Interferon gamma, which falls under the umbrella field of Microglia.

The Interleukin study combines topics in areas such as NADPH oxidase, Lipid peroxidation, Biochemistry, Neuroprotection and Excitotoxicity. Shuxian Hu regularly links together related areas like Innate immune system in his CD8 studies. Immune system and Cytotoxic T cell are frequently intertwined in his study.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Role of Microglia in Central Nervous System Infections

R. Bryan Rock;Genya Gekker;Shuxian Hu;Wen S. Sheng.
Clinical Microbiology Reviews (2004)

726 Citations

Cytokine Effects on Glutamate Uptake by Human Astrocytes

Shuxian Hu;Wen S. Sheng;Laura C. Ehrlich;Phillip K. Peterson.
Neuroimmunomodulation (2000)

422 Citations

Morphine induces apoptosis of human microglia and neurons.

Shuxian Hu;Wen S. Sheng;James R. Lokensgard;Phillip K. Peterson.
Neuropharmacology (2002)

372 Citations

Cytokine-stimulated astrocytes damage human neurons via a nitric oxide mechanism.

Chun C. Chao;Shuxian Hu;Wen S. Sheng;Dingfang Bu.
Glia (1996)

341 Citations

Differential Production of and Migratory Response to β Chemokines by Human Microglia and Astrocytes

Phillip K. Peterson;Shuxian Hu;Janeen Salak-Johnson;Thomas W. Molitor.
The Journal of Infectious Diseases (1997)

285 Citations

Synthetic cannabinoid WIN55,212‐2 inhibits generation of inflammatory mediators by IL‐1β‐stimulated human astrocytes

Wen S. Sheng;Shuxian Hu;Xinan Min;Guy A. Cabral.
Glia (2005)

277 Citations

Cutting Edge: TLR2-Mediated Proinflammatory Cytokine and Chemokine Production by Microglial Cells in Response to Herpes Simplex Virus

Rajagopal N. Aravalli;Shuxian Hu;Timothy N. Rowen;Joseph M. Palmquist.
Journal of Immunology (2005)

266 Citations

Cytokine Regulation of Human Microglial Cell IL-8 Production

Laura C. Ehrlich;Shuxian Hu;Wen S. Sheng;Richard L. Sutton.
Journal of Immunology (1998)

255 Citations

Anti-HIV-1 activity of propolis in CD4 + lymphocyte and microglial cell cultures

Genya Gekker;Shuxian Hu;Marla Spivak;James R. Lokensgard.
Journal of Ethnopharmacology (2005)

197 Citations

Activated microglia inhibit multiplication of Toxoplasma gondii via a nitric oxide mechanism.

C. C. Chao;W. R. Anderson;Shuxian Hu;G. Gekker.
Clinical Immunology and Immunopathology (1993)

196 Citations

Best Scientists Citing Shuxian Hu

Wen-Zhe Ho

Wen-Zhe Ho

Temple University

Publications: 51

Avindra Nath

Avindra Nath

National Institutes of Health

Publications: 33

Shilpa Buch

Shilpa Buch

University of Nebraska Medical Center

Publications: 29

Annamaria Vezzani

Annamaria Vezzani

Mario Negri Institute for Pharmacological Research

Publications: 28

Thomas J. Rogers

Thomas J. Rogers

Temple University

Publications: 27

Jau-Shyong Hong

Jau-Shyong Hong

National Institutes of Health

Publications: 25

Kalipada Pahan

Kalipada Pahan

Rush University Medical Center

Publications: 23

Teresa Ravizza

Teresa Ravizza

Mario Negri Institute for Pharmacological Research

Publications: 20

Yasuhiro Suzuki

Yasuhiro Suzuki

University of Kentucky

Publications: 20

Howard E. Gendelman

Howard E. Gendelman

University of Nebraska Medical Center

Publications: 20

J. Stephen Dumler

J. Stephen Dumler

Uniformed Services University of the Health Sciences

Publications: 19

Michael Maes

Michael Maes

Chulalongkorn University

Publications: 18

Sabita Roy

Sabita Roy

University of Miami

Publications: 17

Phillip K. Peterson

Phillip K. Peterson

University of Minnesota

Publications: 17

Linda R. Watkins

Linda R. Watkins

University of Colorado Boulder

Publications: 17

William J. Britt

William J. Britt

University of Alabama at Birmingham

Publications: 16

Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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