His primary areas of investigation include Cell biology, Endocytosis, Endocytic cycle, Endosome and Signal transduction. The various areas that Mark von Zastrow examines in his Cell biology study include AMPA receptor, Kainate receptor, Long-term depression and Silent synapse. Mark von Zastrow combines subjects such as Synaptic pharmacology, Synaptic augmentation, Metaplasticity and Synaptic scaling with his study of AMPA receptor.
His Endocytosis study is focused on Receptor in general. Mark von Zastrow interconnects Actin cytoskeleton and Dynamin in the investigation of issues within Endocytic cycle. His G protein-coupled receptor research is multidisciplinary, incorporating elements of Heterotrimeric G protein and Clathrin.
His scientific interests lie mostly in Cell biology, Receptor, G protein-coupled receptor, Endocytosis and Endocytic cycle. His study in Endosome, Signal transduction, G protein, Cell signaling and Transport protein falls under the purview of Cell biology. His Receptor study frequently intersects with other fields, such as Neuroscience.
His G protein-coupled receptor study integrates concerns from other disciplines, such as Heterotrimeric G protein, Ubiquitin, Computational biology and Second messenger system. The study incorporates disciplines such as Downregulation and upregulation and Cell membrane in addition to Endocytosis. His Opioid study combines topics from a wide range of disciplines, such as Pharmacology and Desensitization.
The scientist’s investigation covers issues in G protein-coupled receptor, Receptor, Cell biology, G protein and Endocytic cycle. His research in G protein-coupled receptor intersects with topics in Chemical biology, Computational biology and Second messenger system. The Receptor study combines topics in areas such as Biophysics and Protein kinase A.
Mark von Zastrow does research in Cell biology, focusing on Endosome specifically. His study explores the link between Endocytic cycle and topics such as Adenylyl cyclase that cross with problems in Effector. Mark von Zastrow interconnects Transduction, Opioid and Pharmacology in the investigation of issues within Agonist.
Mark von Zastrow spends much of his time researching Coronavirus disease 2019, Cell biology, G protein-coupled receptor, Government and Severe acute respiratory syndrome coronavirus 2. Cell biology is often connected to Receptor in his work. The study incorporates disciplines such as Regulator, Chemical biology and Transduction in addition to Receptor.
His Government research is multidisciplinary, incorporating perspectives in Climate change, Public relations, China, Water resources and Tree planting. The Severe acute respiratory syndrome coronavirus 2 study which covers Contact tracing that intersects with Viral spread and Coronavirus. Mark von Zastrow has researched G protein in several fields, including Agonist, Cell signaling and Endosome.
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A SARS-CoV-2 protein interaction map reveals targets for drug repurposing.
David E. Gordon;Gwendolyn M. Jang;Mehdi Bouhaddou;Jiewei Xu.
Control of Synaptic Strength by Glial TNFα
Eric C. Beattie;David Stellwagen;Wade Morishita;Jacqueline C. Bresnahan.
Functional Selectivity and Classical Concepts of Quantitative Pharmacology
Jonathan D. Urban;William P. Clarke;Mark Von Zastrow;David E. Nichols.
Journal of Pharmacology and Experimental Therapeutics (2007)
Endocytosis and signalling: intertwining molecular networks
Alexander Sorkin;Mark von Zastrow.
Nature Reviews Molecular Cell Biology (2009)
Signal transduction and endocytosis: close encounters of many kinds.
Alexander Sorkin;Mark von Zastrow.
Nature Reviews Molecular Cell Biology (2002)
Role of AMPA receptor cycling in synaptic transmission and plasticity.
Christian Lüscher;Houhui Xia;Eric C Beattie;Reed C Carroll.
A kinase-regulated PDZ-domain interaction controls endocytic sorting of the β2-adrenergic receptor
Tracy T. Cao;Heather W. Deacon;David Reczek;Anthony Bretscher.
Regulation of GPCRs by Endocytic Membrane Trafficking and Its Potential Implications
Aylin C Hanyaloglu;Mark von Zastrow.
Annual Review of Pharmacology and Toxicology (2008)
Conformational biosensors reveal GPCR signalling from endosomes
Roshanak Irannejad;Jin C. Tomshine;Jon R. Tomshine;Michael Chevalier.
Regulation of μ-opioid receptors: desensitization, phosphorylation, internalization, and tolerance.
John T. Williams;Susan L. Ingram;Graeme Henderson;Charles Chavkin.
Pharmacological Reviews (2013)
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