D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 94 Citations 30,353 451 World Ranking 4867 National Ranking 2746

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Gene
  • Endocrinology

His primary areas of study are Internal medicine, Endocrinology, Methadone, Opioid and Addiction. His Internal medicine research incorporates elements of Gastroenterology and Craving. Mary Jeanne Kreek has included themes like Receptor, Opioid antagonist and κ-opioid receptor in his Endocrinology study.

Buprenorphine is closely connected to Heroin in his research, which is encompassed under the umbrella topic of Methadone. His work in Opioid tackles topics such as Pharmacology which are related to areas like Agonist, Dynorphin and μ-opioid receptor. His Addiction research includes themes of Drug, Substance abuse, Endogenous opioid and Opiate.

His most cited work include:

  • Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity : possible implications for opiate addiction (935 citations)
  • Genetic Influences on Impulsivity, Risk Taking, Stress Responsivity and Vulnerability to Drug Abuse and Addiction (808 citations)
  • Stress, Dysregulation of Drug Reward Pathways, and the Transition to Drug Dependence (690 citations)

What are the main themes of his work throughout his whole career to date?

His scientific interests lie mostly in Internal medicine, Endocrinology, Pharmacology, Methadone and Addiction. Internal medicine is represented through his Adrenocorticotropic hormone, Dynorphin, Naltrexone, Prolactin and Endogenous opioid research. Mary Jeanne Kreek frequently studies issues relating to Receptor and Endocrinology.

His research investigates the connection between Pharmacology and topics such as Opioid that intersect with issues in Morphine. His work deals with themes such as Buprenorphine and Narcotic, which intersect with Methadone. Mary Jeanne Kreek focuses mostly in the field of Addiction, narrowing it down to topics relating to Heroin and, in certain cases, Substance abuse.

He most often published in these fields:

  • Internal medicine (44.54%)
  • Endocrinology (37.15%)
  • Pharmacology (25.88%)

What were the highlights of his more recent work (between 2013-2021)?

  • Internal medicine (44.54%)
  • Endocrinology (37.15%)
  • Pharmacology (25.88%)

In recent papers he was focusing on the following fields of study:

His primary areas of investigation include Internal medicine, Endocrinology, Pharmacology, Opioid and Addiction. His Internal medicine research incorporates themes from Alcohol and Genotype. His Pharmacology study integrates concerns from other disciplines, such as Agonist, μ-opioid receptor, Antagonist and κ-opioid receptor.

His Opioid research also works with subjects such as

  • Age of onset most often made with reference to Cocaine dependence,
  • Pharmacotherapy and related Disease. His Addiction study combines topics in areas such as Genetics, Single-nucleotide polymorphism and Heroin. The various areas that Mary Jeanne Kreek examines in his Heroin study include Methadone, Methadone maintenance, Gene and Cannabis.

Between 2013 and 2021, his most popular works were:

  • Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts (72 citations)
  • Stress-related genes and heroin addiction: A role for a functional FKBP5 haplotype (41 citations)
  • Extended access oxycodone self-administration and neurotransmitter receptor gene expression in the dorsal striatum of adult C57BL/6 J mice (41 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Enzyme

His main research concerns Pharmacology, Opioid, Addiction, Internal medicine and Heroin. His studies in Pharmacology integrate themes in fields like Striatum, Agonist, μ-opioid receptor, κ-opioid receptor and Oxycodone. The study incorporates disciplines such as SNP, Single-nucleotide polymorphism, Genetics, Case-control study and Allele frequency in addition to Addiction.

His Internal medicine research includes elements of Endocrinology and Polyunsaturated fatty acid, Fatty acid. His study in Endocrinology is interdisciplinary in nature, drawing from both Alcohol and Opioid receptor. His work in Heroin covers topics such as Methadone maintenance which are related to areas like Nod.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Single-nucleotide polymorphism in the human mu opioid receptor gene alters beta-endorphin binding and activity : possible implications for opiate addiction

Cherie Bond;K. Steven LaForge;Mingting Tian;Dorothy Melia.
Proceedings of the National Academy of Sciences of the United States of America (1998)

1290 Citations

Genetic Influences on Impulsivity, Risk Taking, Stress Responsivity and Vulnerability to Drug Abuse and Addiction

Mary Jeanne Kreek;David A Nielsen;Eduardo R Butelman;K Steven LaForge.
Nature Neuroscience (2005)

1265 Citations

Stress, Dysregulation of Drug Reward Pathways, and the Transition to Drug Dependence

George Koob;Mary Jeanne Kreek.
American Journal of Psychiatry (2007)

915 Citations

Drug dependence: stress and dysregulation of brain reward pathways.

Mary Jeanne Kreek;George F. Koob.
Drug and Alcohol Dependence (1998)

872 Citations

Stress-Induced Cocaine Craving and Hypothalamic-Pituitary-Adrenal Responses Are Predictive of Cocaine Relapse Outcomes

Rajita Sinha;Miguel Garcia;Prashni Paliwal;Mary Jeanne Kreek.
Archives of General Psychiatry (2006)

543 Citations

HIV-1 Infection Among Intravenous Drug Users in Manhattan, New York City, From 1977 Through 1987

Don C. Des Jarlais;Samuel R. Friedman;David M. Novick;Jo L. Sotheran.
JAMA (1989)

530 Citations

Effective medical treatment of opiate addiction

L. L. Judd;M. G. Marston;C. Attkisson;W. Berrettini.
JAMA (1998)

506 Citations

Pharmacotherapy of addictions

Mary Jeanne Kreek;K. Steven LaForge;Eduardo Butelman.
Nature Reviews Drug Discovery (2002)

505 Citations

Naltrexone decreases craving and alcohol self- administration in alcohol-dependent subjects and activates the hypothalamo--pituitary--adrenocortical axis.

Stephanie S O'Malley;Suchitra Krishnan-Sarin;Conor Farren;Rajita Sinha.
Psychopharmacology (2002)

486 Citations

1-year retention and social function after buprenorphine-assisted relapse prevention treatment for heroin dependence in Sweden: a randomised, placebo-controlled trial.

Johan Kakko;Kerstin Dybrandt Svanborg;Mary Jeanne Kreek;Markus Heilig.
The Lancet (2003)

482 Citations

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