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Medicine

D-Index
106
Citations
34375
World Ranking
6611
National Ranking
136

Overview

Markus Heilig is affiliated with Linköping University in Sweden and has contributed extensively to research in neuroscience and medicine. Their work spans various subfields including cellular and molecular neuroscience, cognitive neuroscience, clinical psychology, molecular biology, and pharmacology.

The research topics covered by Heilig include:

  • Neurotransmitter receptor influence on behavior
  • Substance abuse treatment and outcomes
  • Cannabis and cannabinoid research
  • Stress responses and cortisol
  • Neural and behavioral psychology studies
  • Alcohol consumption and health effects
  • Neuropeptides and animal physiology

Heilig has published several notable papers. Among their recent works are:

  • "Addiction as a brain disease revised: why it still matters, and the need for consilience," 2021, Neuropsychopharmacology
  • "Improving translation of animal models of addiction and relapse by reverse translation," 2020, Nature Reviews Neuroscience
  • "Hazardous drinking and alcohol use disorders," 2022, Nature Reviews Disease Primers
  • "Microglial activation elicits a negative affective state through prostaglandin-mediated modulation of striatal neurons," 2021, Immunity
  • "Repetitive Transcranial Magnetic Stimulation in Alcohol Dependence: A Randomized, Double-Blind, Sham-Controlled Proof-of-Concept Trial Targeting the Medial Prefrontal and Anterior Cingulate Cortices," 2021, Biological Psychiatry

Frequent co-authors in Heilig's body of work include:

  • Anthony A. Grace
  • Harriet de Wit
  • Joel Gelernter
  • Anissa Abi-Dargham
  • New York

The scientist has published numerous articles in reputable venues, with the following being among the most frequent:

  • Biological Psychiatry (42 publications)
  • Neuropsychopharmacology (12 publications)
  • Molecular Psychiatry (6 publications)
  • Alcohol (6 publications)
  • Psychopharmacology (5 publications)

Overall, Markus Heilig's research focuses predominantly on neuroscience, with an emphasis on understanding brain mechanisms related to addiction, substance abuse treatment, and behavioral psychology. Their contributions integrate molecular and cellular neuroscience with clinical and cognitive perspectives, supporting interdisciplinary approaches in medical research.

Best Publications

  • The NPY system in stress, anxiety and depression.

    Markus Heilig

  • Modulation of anxiety and neuropeptide Y-Y1 receptors by antisense oligodeoxynucleotides

    Claes Wahlestedt;Emilio Merlo Pich;George F. Koob;Frances Yee

  • A key role for corticotropin-releasing factor in alcohol dependence

    Markus Heilig;George F. Koob

  • 1-year retention and social function after buprenorphine-assisted relapse prevention treatment for heroin dependence in Sweden: a randomised, placebo-controlled trial.

    Johan Kakko;Kerstin Dybrandt Svanborg;Mary Jeanne Kreek;Markus Heilig

  • Alcohol use disorders

    Andre F Carvalho;Markus Heilig;Augusto Perez;Charlotte Probst

  • Neuropeptide systems as novel therapeutic targets for depression and anxiety disorders

    Andrew Holmes;Markus Heilig;Nadia M.J. Rupniak;Thomas Steckler

  • Acute withdrawal, protracted abstinence and negative affect in alcoholism: Are they linked?

    Markus Heilig;Mark Egli;John C. Crabbe;Howard C. Becker

  • Requirement of central ghrelin signaling for alcohol reward

    Elisabet Jerlhag;Emil Egecioglu;Sara Landgren;Nicolas Salomé

  • Pharmacological treatment of alcohol dependence: Target symptoms and target mechanisms

    Markus Heilig;Mark Egli

  • Centrally administered neuropeptide Y (NPY) produces anxiolytic-like effects in animal anxiety models.

    Markus Heilig;Bo Söderpalm;Jörgen A. Engel;Erik Widerlöv

  • Anxiolytic-like action of neuropeptide Y: mediation by Y1 receptors in amygdala, and dissociation from food intake effects.

    Markus Heilig;Sarah McLeod;Michelle Brot;Steven C. Heinrichs

  • Corticotropin-releasing factor and neuropeptide Y: role in emotional integration.

    Markus Heilig;George F. Koob;Rolf Ekman;Karen T. Britton

  • Behavioral insensitivity to restraint stress, absent fear suppression of behavior and impaired spatial learning in transgenic rats with hippocampal neuropeptide Y overexpression

    A. Thorsell;M. Michalkiewicz;Y. Dumont;R. Quirion

  • Long-lasting increase in voluntary ethanol consumption and transcriptional regulation in the rat brain after intermittent exposure to alcohol

    Roberto Rimondini;Christina Arlinde;Wolfgang Sommer;Markus Heilig

  • Corticosteroid-Dependent Plasticity Mediates Compulsive Alcohol Drinking in Rats

    Leandro F. Vendruscolo;Estelle Barbier;Joel E. Schlosburg;Kaushik K. Misra

  • 3-(4-Chloro-2-morpholin-4-yl-thiazol-5-yl)-8-(1-ethylpropyl)-2,6-dimethyl-imidazo[1,2-b]pyridazine : a novel brain-penetrant, orally available corticotropin-releasing factor receptor 1 antagonist with efficacy in animal models of alcoholism

    Donald R. Gehlert;Andrea Cippitelli;Annika Thorsell;Anh Dzung Lê

  • Upregulation of voluntary alcohol intake, behavioral sensitivity to stress, and amygdala crhr1 expression following a history of dependence.

    Wolfgang H. Sommer;Roberto Rimondini;Anita C. Hansson;Philip A. Hipskind

  • Neuropeptide Y (NPY) in the area of the hypothalamic paraventricular nucleus activates the pituitary-adrenocortical axis in the rat

    Claes Wahlestedt;Gunnar Skagerberg;Rolf Ekman;Markus Heilig

  • A genetic determinant of the striatal dopamine response to alcohol in men

    Vijay A. Ramchandani;John Umhau;Francisco J. Pavon;Victor Ruiz-Velasco

  • Chronic alcohol neuroadaptation and stress contribute to susceptibility for alcohol craving and relapse.

    George R. Breese;Rajita Sinha;Markus Heilig

Frequent Co-Authors

Wolfgang H. Sommer
Wolfgang H. Sommer Heidelberg University
Melanie L. Schwandt
Melanie L. Schwandt National Institutes of Health
Roberto Ciccocioppo
Roberto Ciccocioppo University of Camerino
Anita C. Hansson
Anita C. Hansson Central Institute of Mental Health
Claes Wahlestedt
Claes Wahlestedt University of Miami
Roberto Rimondini
Roberto Rimondini University of Bologna
Reza Momenan
Reza Momenan National Institutes of Health
Stephen J. Suomi
Stephen J. Suomi National Institutes of Health
David Goldman
David Goldman National Institutes of Health
Daniel W. Hommer
Daniel W. Hommer National Institutes of Health

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