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Immunology

D-Index
49
Citations
10836
World Ranking
4319
National Ranking
1964

Overview

Chihiro Morishima is affiliated with the University of Washington in the United States and has contributed extensively to the field of medicine, with a particular focus on infectious diseases. Their research prominently addresses SARS-CoV-2 and COVID-19, covering clinical studies, detection methods, and immune responses.

The scientist's work spans several subfields including infectious diseases, immunology, molecular biology, oncology, and hematology. Morishima's research interests are primarily centered around topics such as SARS-CoV-2 and COVID-19 research, COVID-19 clinical research studies, SARS-CoV-2 detection and testing, immunotherapy and immune responses, CAR-T cell therapy research, cancer immunotherapy and biomarkers, as well as T-cell and B-cell immunology.

Morishima's publications appear frequently in a variety of scientific journals. Notable publication venues include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • American Journal of Clinical Pathology
  • Journal of Clinical Microbiology
  • JCI Insight
  • The Journal of Immunology

Frequent collaborative partners in Morishima's research include colleagues Mark H. Wener, Susan L. Fink, Andrew Bryan, Anu Chaudhary, and Alexander L. Greninger.

Recent papers authored or co-authored by Morishima feature studies on SARS-CoV-2 detection and immune response, including:

  • Performance Characteristics of the Abbott Architect SARS-CoV-2 IgG Assay and Seroprevalence in Boise, Idaho (2020, Journal of Clinical Microbiology)
  • Sensitivity in Detection of Antibodies to Nucleocapsid and Spike Proteins of Severe Acute Respiratory Syndrome Coronavirus 2 in Patients With Coronavirus Disease 2019 (2020, The Journal of Infectious Diseases)
  • Detection of Nucleocapsid Antibody to SARS-CoV-2 is More Sensitive than Antibody to Spike Protein in COVID-19 Patients (2020, bioRxiv [Cold Spring Harbor Laboratory])
  • Flt3 ligand augments immune responses to anti-DEC-205-NY-ESO-1 vaccine through expansion of dendritic cell subsets (2020, Nature Cancer)
  • Prevalence of autoantibody responses in acute coronavirus disease 2019 (COVID-19) (2020, Journal of Translational Autoimmunity)

The breadth of Morishima's portfolio indicates a focus on both fundamental immunologic mechanisms and applied clinical research, particularly in the context of emergent viral pathogens and immune therapies related to infectious diseases and oncology.

Best Publications

  • Incidence of Hepatocellular Carcinoma and Associated Risk Factors in Hepatitis C-Related Advanced Liver Disease

    Anna S. Lok;Leonard B. Seeff;Timothy R. Morgan;Adrian M. di Bisceglie

  • Peginterferon alfa-2a and ribavirin in patients with chronic hepatitis C who have failed prior treatment.

    Mitchell L. Shiffman;Adrian M. Di Bisceglie;Karen L. Lindsay;Chihiro Morishima

  • Performance Characteristics of the Abbott Architect SARS-CoV-2 IgG Assay and Seroprevalence in Boise, Idaho.

    Andrew Bryan;Gregory Pepper;Mark H. Wener;Susan L. Fink

  • Outcome of sustained virological responders with histologically advanced chronic hepatitis C

    Timothy R. Morgan;Timothy R. Morgan;Marc G. Ghany;Hae Young Kim;Kristin K. Snow

  • Prolonged Therapy of Advanced Chronic Hepatitis C with Low-Dose Peginterferon

    Adrian M. Di Bisceglie;Mitchell L. Shiffman;Gregory T. Everson;Karen L. Lindsay

  • Growth factor-induced acceleration of tissue repair through direct and inductive activities in a rabbit dermal ulcer model.

    T A Mustoe;G F Pierce;C Morishima;T F Deuel

  • Predicting cirrhosis in patients with hepatitis C based on standard laboratory tests: Results of the HALT‐C cohort

    Anna S F Lok;Marc G. Ghany;Zachary D. Goodman;Elizabeth C. Wright

  • Identification of hepatoprotective flavonolignans from silymarin

    Stephen J. Polyak;Chihiro Morishima;Volker Lohmann;Sampa Pal

  • Sensitivity in Detection of Antibodies to Nucleocapsid and Spike Proteins of Severe Acute Respiratory Syndrome Coronavirus 2 in Patients With Coronavirus Disease 2019.

    Peter D Burbelo;Francis X Riedo;Chihiro Morishima;Stephen Rawlings

  • Inhibition of T-Cell Inflammatory Cytokines, Hepatocyte NF-κB Signaling, and HCV Infection by Standardized Silymarin

    Stephen J. Polyak;Chihiro Morishima;Margaret C. Shuhart;Chia C. Wang

  • Decreased NK cell frequency in chronic hepatitis C does not affect ex vivo cytolytic killing.

    Chihiro Morishima;Denise M. Paschal;Chia C. Wang;Christina S. Yoshihara

  • Maintenance peginterferon therapy and other factors associated with hepatocellular carcinoma in patients with advanced hepatitis C

    Anna S. Lok;James E. Everhart;Elizabeth C. Wright;Adrian M. Di Bisceglie

  • Coffee intake is associated with lower rates of liver disease progression in chronic hepatitis C

    Neal D. Freedman;James E. Everhart;Karen L. Lindsay;Marc G. Ghany

  • A First-in-Human Phase I Study of Subcutaneous Outpatient Recombinant Human IL15 (rhIL15) in Adults with Advanced Solid Tumors

    Jeffrey S. Miller;Chihiro Morishima;Douglas G. McNeel;Manish R. Patel

  • Prognostic value of Ishak fibrosis stage: findings from the hepatitis C antiviral long-term treatment against cirrhosis trial.

    James E. Everhart;Elizabeth C. Wright;Zachary D. Goodman;Jules L. Dienstag

  • Impact of disease severity on outcome of antiviral therapy for chronic hepatitis C: Lessons from the HALT-C trial.

    Gregory T. Everson;John C. Hoefs;Leonard B. Seeff;Herbert L. Bonkovsky

  • Phase I Trial of ALT-803, A Novel Recombinant IL15 Complex, in Patients with Advanced Solid Tumors.

    Kim Margolin;Chihiro Morishima;Chihiro Morishima;Vamsidhar Velcheti;Jeffrey S. Miller

  • A prospective study of the rate of progression in compensated, histologically advanced chronic hepatitis C†‡§¶‖

    Jules L. Dienstag;Marc G. Ghany;Timothy R. Morgan;Timothy R. Morgan;Adrian M. Di Bisceglie

  • Detection of Nucleocapsid Antibody to SARS-CoV-2 is More Sensitive than Antibody to Spike Protein in COVID-19 Patients.

    Peter D Burbelo;Francis X Riedo;Chihiro Morishima;Stephen Rawlings

  • Viral oncoprotein antibodies as a marker for recurrence of Merkel cell carcinoma: a prospective validation study

    Kelly G. Paulson;Christopher W. Lewis;Mary W. Redman;William T. Simonson

  • Evolution of the HALT-C Trial: pegylated interferon as maintenance therapy for chronic hepatitis C in previous interferon nonresponders.

    William M. Lee;Jules L. Dienstag;Karen L. Lindsay;Anna S. Lok

  • Predicting cirrhosis in patients with hepatitis C based on standard laboratory tests: Results of the HALT-C cohort Potential conflict of interest: Nothing to report.

    Anna Suk-Fong Lok;Marc G. Ghany;Zachary D. Goodman;Elizabeth C. Wright

Frequent Co-Authors

Herbert L. Bonkovsky
Herbert L. Bonkovsky Wake Forest University
Timothy R. Morgan
Timothy R. Morgan California State University, Long Beach
Adrian M. Di Bisceglie
Adrian M. Di Bisceglie Saint Louis University
Marc G. Ghany
Marc G. Ghany National Institutes of Health
William M. Lee
William M. Lee The University of Texas Southwestern Medical Center
Jules L. Dienstag
Jules L. Dienstag Harvard University
Gregory T. Everson
Gregory T. Everson University of Colorado Denver
James E. Everhart
James E. Everhart National Institutes of Health
Keith R. Jerome
Keith R. Jerome Fred Hutchinson Cancer Research Center
David R. Gretch
David R. Gretch University of Washington

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