His primary scientific interests are in Pharmacology, Internal medicine, Endocrinology, Neuroscience and Ethanol. He has researched Pharmacology in several fields, including Acamprosate, NMDA receptor, Glutamate receptor, Antagonist and Craving. His Craving research includes themes of Neurochemical, Abstinence and Naltrexone.
His work is dedicated to discovering how Internal medicine, Biochemistry are connected with Adult male and Time course and other disciplines. In his study, which falls under the umbrella issue of Endocrinology, Anhedonia, Stressor and Chronic stress is strongly linked to Anxiety. His Ethanol research is multidisciplinary, relying on both Alcohol and Anesthesia, Self-administration.
Rainer Spanagel focuses on Internal medicine, Endocrinology, Neuroscience, Pharmacology and Addiction. His Internal medicine research includes elements of Alcohol and Alcohol dependence. His research in Endocrinology is mostly focused on Dopamine.
The study incorporates disciplines such as Synaptic plasticity and Glutamatergic in addition to Neuroscience. Within one scientific family, he focuses on topics pertaining to NMDA receptor under Pharmacology, and may sometimes address concerns connected to Glutamate receptor. His research integrates issues of Drug, Abstinence and Clinical psychology in his study of Addiction.
Rainer Spanagel mainly investigates Neuroscience, Addiction, Internal medicine, Endocrinology and Pharmacology. His Neuroscience research focuses on Endocannabinoid system and how it relates to Cannabinoid receptor. His studies in Addiction integrate themes in fields like Drug, Abstinence and Clinical psychology.
His Internal medicine research integrates issues from Alcohol, Alcohol dependence and Locus. He combines subjects such as Receptor, Downregulation and upregulation, Wild type and Nicotine with his study of Endocrinology. The Pharmacology study combines topics in areas such as Melatonin, MEK inhibitor, MAPK/ERK pathway and Clinical trial.
Rainer Spanagel mainly focuses on Neuroscience, Addiction, Nucleus accumbens, Pharmacology and Prefrontal cortex. His Neuroscience study frequently links to other fields, such as Endocannabinoid system. His Addiction study combines topics from a wide range of disciplines, such as Clinical psychology, Clinical trial, Drug and Insula.
His study on Nucleus accumbens is covered under Dopamine. His study with Self-administration involves better knowledge in Internal medicine. His Internal medicine research is multidisciplinary, incorporating perspectives in Relapse prevention and Genotype.
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Opposing tonically active endogenous opioid systems modulate the mesolimbic dopaminergic pathway
Rainer Spanagel;Albert Herz;Toni S. Shippenberg.
Proceedings of the National Academy of Sciences of the United States of America (1992)
The dopamine hypothesis of reward: past and current status
Rainer Spanagel;Friedbert Weiss.
Trends in Neurosciences (1999)
Impaired stress response and reduced anxiety in mice lacking a functional corticotropin-releasing hormone receptor 1
Peter Timpl;Rainer Spanagel;Inge Sillaber;Adelheid Kresse.
Nature Genetics (1998)
Alcoholism: a systems approach from molecular physiology to addictive behavior.
Rainer Spanagel.
Physiological Reviews (2009)
Behavioural assessment of drug reinforcement and addictive features in rodents: an overview.
Carles Sanchis-Segura;Rainer Spanagel.
Addiction Biology (2006)
The effects of opioid peptides on dopamine release in the nucleus accumbens : an in vivo microdialysis study
Rainer Spanagel;Albert Herz;Toni S. Shippenberg.
Journal of Neurochemistry (1990)
Neuropharmacology of alcohol addiction.
V Vengeliene;A Bilbao;A Molander;R Spanagel.
British Journal of Pharmacology (2009)
The clock gene Per2 influences the glutamatergic system and modulates alcohol consumption.
Rainer Spanagel;Gurudutt N Pendyala;Carolina Abarca;Tarek Zghoul.
Nature Medicine (2005)
Stress-induced anhedonia in mice is associated with deficits in forced swimming and exploration.
Tatyana Strekalova;Rainer Spanagel;Dusan Bartsch;Fritz A Henn.
Neuropsychopharmacology (2004)
The IMAGEN study: reinforcement-related behaviour in normal brain function and psychopathology.
G Schumann;E Loth;T Banaschewski;A Barbot.
Molecular Psychiatry (2010)
Addiction Biology
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