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Neuroscience

D-Index
71
Citations
15528
World Ranking
2443
National Ranking
1155

Overview

Eric P. Zorrilla is affiliated with the Scripps Research Institute in the United States. Their research focuses on neuroscience, medicine, and psychology, with specific expertise in behavioral neuroscience, clinical psychology, and cellular and molecular neuroscience. Additional subfields include endocrinology, diabetes and metabolism, and pharmacology.

The main topics covered in Zorrilla's work include:

  • Stress Responses and Cortisol
  • Eating Disorders and Behaviors
  • Hormonal Regulation and Hypertension
  • Neurotransmitter Receptor Influence on Behavior
  • Neuroendocrine Regulation and Behavior
  • Adipose Tissue and Metabolism
  • Tryptophan and Brain Disorders

Recent publications illustrate a focus on alcohol dependence, stress-related disorders, and compulsive behaviors. Selected papers include:

  • A novel mouse model for vulnerability to alcohol dependence induced by early-life adversity (2020) in Neurobiology of Stress
  • Converging vulnerability factors for compulsive food and drug use (2021) in Neuropharmacology
  • FKBP5 inhibitors modulate alcohol drinking and trauma-related behaviors in a model of comorbid post-traumatic stress and alcohol use disorder (2022) in Neuropsychopharmacology
  • Chemogenetic inhibition of central amygdala CRF-expressing neurons decreases alcohol intake but not trauma-related behaviors in a rat model of post-traumatic stress and alcohol use disorder (2024) in Molecular Psychiatry
  • Glucocorticoid Receptor Antagonist Mifepristone Does Not Alter Innate Anxiety-Like Behavior in Genetically-Selected Marchigian Sardinian (msP) Rats (2021) in International Journal of Molecular Sciences

Frequent coauthors in Zorrilla's work include:

  • Marisa Roberto
  • Bryan Cruz
  • Valentina Vozella
  • Dean Kirson
  • Luísa Becker Bertotto

Zorrilla regularly publishes in venues such as:

  • Neuropharmacology
  • Cells
  • British Journal of Pharmacology
  • Neurobiology of Stress
  • Neuropsychopharmacology

Best Publications

  • The relationship of depression and stressors to immunological assays: a meta-analytic review.

    Eric P. Zorrilla;Lester Luborsky;James R. McKay;Robert Rosenthal

  • Compulsive drug-seeking behavior and relapse. Neuroadaptation, stress, and conditioning factors.

    Friedbert Weiss;Roberto Ciccocioppo;Loren H. Parsons;Simon Katner

  • Increased ethanol self-administration and anxiety-like behavior during acute ethanol withdrawal and protracted abstinence: regulation by corticotropin-releasing factor.

    Glenn R. Valdez;Amanda J. Roberts;Karen Chan;Heather Davis

  • Transgenic mice with a reduced core body temperature have an increased life span

    Bruno Conti;Manuel Sanchez-Alavez;Raphaelle Winsky-Sommerer;Maria Concetta Morale

  • Corticotropin releasing factor-induced amygdala gamma-aminobutyric Acid release plays a key role in alcohol dependence.

    Marisa Roberto;Maureen T. Cruz;Nicholas W. Gilpin;Valentina Sabino;Valentina Sabino

  • Corticosteroid-Dependent Plasticity Mediates Compulsive Alcohol Drinking in Rats

    Leandro F. Vendruscolo;Estelle Barbier;Joel E. Schlosburg;Kaushik K. Misra

  • Corticotropin-releasing factor 1 antagonists selectively reduce ethanol self-administration in ethanol-dependent rats.

    Cindy K. Funk;Eric P. Zorrilla;Mei-Jing Lee;Kenner C. Rice

  • The dark side of food addiction

    Sarah L. Parylak;George F. Koob;George F. Koob;Eric P. Zorrilla;Eric P. Zorrilla

  • Vaccination against weight gain

    Eric P. Zorrilla;Shinichi Iwasaki;Jason A. Moss;Jason Chang

  • CRF–CRF1 system activation mediates withdrawal-induced increases in nicotine self-administration in nicotine-dependent rats

    Olivier George;Sandy Ghozland;Marc R. Azar;Pietro Cottone

  • Corticotropin releasing factor: a key role in the neurobiology of addiction.

    Eric P. Zorrilla;Marian L. Logrip;George F. Koob

  • Changes in levels of regional CRF-like-immunoreactivity and plasma corticosterone during protracted drug withdrawal in dependent rats.

    Eric P. Zorrilla;Glenn R. Valdez;Friedbert Weiss

  • Physiology, pharmacology, and therapeutic relevance of urocortins in mammals: ancient CRF paralogs.

    Éva M. Fekete;Eric P. Zorrilla

  • CRF system recruitment mediates dark side of compulsive eating

    Pietro Cottone;Valentina Sabino;Marisa Roberto;Michal Bajo

  • Systemic κ-opioid receptor antagonism by nor-binaltorphimine reduces dependence-induced excessive alcohol self-administration in rats.

    Brendan M. Walker;Eric P. Zorrilla;George F. Koob

  • The therapeutic potential of CRF1 antagonists for anxiety

    Eric P Zorrilla;George F Koob

  • Interleukin-18 controls energy homeostasis by suppressing appetite and feed efficiency

    Eric P. Zorrilla;Manuel Sanchez-Alavez;Shuei Sugama;Molly Brennan

  • Progress in corticotropin-releasing factor-1 antagonist development.

    Eric P. Zorrilla;George F. Koob

  • Exposure to Repetitive Versus Varied Stress during Prenatal Development Generates Two Distinct Anxiogenic and Neuroendocrine Profiles in Adulthood

    Heather N. Richardson;Eric P. Zorrilla;Chitra D. Mandyam;Catherine L. Rivier

  • Neurobiological mechanisms of addiction: focus on corticotropin-releasing factor.

    George F Koob;Eric P Zorrilla

  • Sigma-1 receptor knockout mice display a depressive-like phenotype

    Valentina Sabino;Pietro Cottone;Sarah L. Parylak;Sarah L. Parylak;Luca Steardo

  • Role of corticotropin-releasing factor in drug addiction: potential for pharmacological intervention.

    Marian L. Logrip;George F. Koob;Eric P. Zorrilla

Frequent Co-Authors

Marisa Roberto
Marisa Roberto Scripps Research Institute
Loren H. Parsons
Loren H. Parsons Scripps Research Institute
Tamas Bartfai
Tamas Bartfai Stockholm University
Olivier George
Olivier George University of California, San Diego
Lester Luborsky
Lester Luborsky University of Pennsylvania
James R. McKay
James R. McKay University of Pennsylvania
Robert J. DeRubeis
Robert J. DeRubeis University of Pennsylvania
Rémi Martin-Fardon
Rémi Martin-Fardon Scripps Research Institute
Raquel E. Gur
Raquel E. Gur University of Pennsylvania
Catherine Rivier
Catherine Rivier Salk Institute for Biological Studies

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