D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Medicine D-index 176 Citations 125,796 685 World Ranking 144 National Ranking 100

Research.com Recognitions

Awards & Achievements

2000 - Member of the National Academy of Medicine (NAM)

1992 - Member of the National Academy of Sciences

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Endocrinology
  • Gene

The scientist’s investigation covers issues in Internal medicine, Endocrinology, Receptor, Peptide hormone and Hypothalamus. His study in Internal medicine focuses on Corticotropin-releasing hormone, Pituitary gland, Secretion, Somatostatin and Anterior pituitary. His Corticotropin-releasing hormone study combines topics in areas such as Endorphins, Vasopressin and In vivo.

Wylie Vale combines subjects such as Peptide, Somatotropic cell, Prolactin and Growth hormone secretion with his study of Somatostatin. His Endocrinology study frequently draws connections to adjacent fields such as Neuropeptide. His work is dedicated to discovering how Receptor, Molecular biology are connected with Activin type 2 receptors, ACVR2B, Peptide sequence and Activin receptor and other disciplines.

His most cited work include:

  • Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin (4054 citations)
  • Hypothalamic Polypeptide That Inhibits the Secretion of Immunoreactive Pituitary Growth Hormone (3060 citations)
  • Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing (2044 citations)

What are the main themes of his work throughout his whole career to date?

Wylie Vale mostly deals with Internal medicine, Endocrinology, Receptor, Peptide hormone and Somatostatin. His studies in Urocortin, Corticotropin-releasing hormone, Antagonist, Gonadotropin-releasing hormone and Luteinizing hormone are all subfields of Internal medicine research. His studies in Corticotropin-releasing hormone integrate themes in fields like Vasopressin and Adrenocorticotropic hormone.

His is doing research in Pituitary gland, Hormone, Secretion, Hypothalamus and Anterior pituitary, both of which are found in Endocrinology. The various areas that he examines in his Receptor study include Molecular biology and Cell biology. His research in Somatostatin intersects with topics in Glucagon and Growth hormone secretion.

He most often published in these fields:

  • Internal medicine (78.00%)
  • Endocrinology (77.34%)
  • Receptor (19.25%)

What were the highlights of his more recent work (between 2000-2019)?

  • Internal medicine (78.00%)
  • Endocrinology (77.34%)
  • Receptor (19.25%)

In recent papers he was focusing on the following fields of study:

His primary areas of study are Internal medicine, Endocrinology, Receptor, Urocortin and Cell biology. His Follistatin, Corticosterone, Anterior pituitary, Pituitary gland and Gonadotropic cell study are his primary interests in Internal medicine. His study looks at the intersection of Pituitary gland and topics like Endocrine gland with Somatotropic cell.

His research in Endocrinology intersects with topics in Agonist and Signal transduction. Wylie Vale has researched Urocortin in several fields, including Neuropeptide, Heart failure and Adrenocorticotropic hormone. His work carried out in the field of Cell biology brings together such families of science as Mutant and Bone morphogenetic protein.

Between 2000 and 2019, his most popular works were:

  • CRF and CRF receptors: role in stress responsivity and other behaviors. (1025 citations)
  • Identification of urocortin III, an additional member of the corticotropin-releasing factor (CRF) family with high affinity for the CRF2 receptor (811 citations)
  • The role of the hypothalamic-pituitary-adrenal axis in neuroendocrine responses to stress. (799 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Gene
  • Enzyme

Wylie Vale mainly focuses on Internal medicine, Endocrinology, Receptor, Urocortin and Cell biology. The study incorporates disciplines such as Signal transduction and Peptide in addition to Internal medicine. His Endocrinology study frequently involves adjacent topics like Gastric emptying.

His Receptor research focuses on Peptide sequence and how it connects with Alternative splicing and Molecular biology. His Urocortin study incorporates themes from Elevated plus maze, Corticotropin-Releasing Factor Receptor 1 and Agonist. Wylie Vale works mostly in the field of Cell biology, limiting it down to topics relating to Cell growth and, in certain cases, Protein kinase B, Mitogen-activated protein kinase, Cell adhesion, PI3K/AKT/mTOR pathway and Smad2 Protein.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Characterization of a 41-residue ovine hypothalamic peptide that stimulates secretion of corticotropin and beta-endorphin

Wylie Vale;Joachim Spiess;Catherine Rivier;Jean Rivier.
Science (1981)

7702 Citations

Hypothalamic Polypeptide That Inhibits the Secretion of Immunoreactive Pituitary Growth Hormone

Paul Brazeau;Wylie Vale;Roger Burgus;Nicholas Ling.
Science (1973)

5261 Citations

Production of a novel neuropeptide encoded by the calcitonin gene via tissue-specific RNA processing

Michael G. Rosenfeld;Jean-Jacques Mermod;Susan G. Amara;Larry W. Swanson.
Nature (1983)

2705 Citations

Organization of Ovine Corticotropin-Releasing Factor Immunoreactive Cells and Fibers in the Rat Brain: An Immunohistochemical Study

L.W. Swanson;P.E. Sawchenko;J. Rivier;W.W. Vale.
Neuroendocrinology (1983)

2275 Citations

Elevated concentrations of CSF corticotropin-releasing factor-like immunoreactivity in depressed patients

Charles B. Nemeroff;Erik Widerlov;Garth Bissette;Helena Walleus.
Science (1984)

2153 Citations

beta-Endorphin and adrenocorticotropin are selected concomitantly by the pituitary gland

Roger Guillemin;Therese Vargo;Jean Rossier;Scott Minick.
Science (1977)

1776 Citations

Interleukin-1 stimulates the secretion of hypothalamic corticotropin-releasing factor.

Robert Sapolsky;Catherine Rivier;Gayle Yamamoto;Paul Plotsky.
Science (1987)

1771 Citations

Urocortin, a mammalian neuropeptide related to fish urotensin I and to corticotropin-releasing factor

Joan Vaughan;Cynthia Donaldson;Jackson Bittencourt;Marilyn H. Perrin.
Nature (1995)

1643 Citations

CRF and CRF receptors: role in stress responsivity and other behaviors.

Tracy L. Bale;Wylie W. Vale.
Annual Review of Pharmacology and Toxicology (2004)

1639 Citations

Characterization of a growth hormone-releasing factor from a human pancreatic islet tumour.

Jean Rivier;Joachim Spiess;Michael Thorner;Wylie Vale.
Nature (1982)

1572 Citations

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