World's Best Scientists 2026 revealed!

D-Index & Metrics

Medicine

D-Index
81
Citations
19179
World Ranking
16817
National Ranking
883

Overview

Jörn Lötsch is affiliated with Goethe University Frankfurt in Germany and has a research portfolio centered on medicine and biochemistry, genetics, and molecular biology. Their work spans molecular biology, artificial intelligence, physiology, sensory systems, and pharmacology, reflecting a multidisciplinary approach to biomedical research.

The scientist has contributed extensively to several key topics, including:

  • Olfactory and Sensory Function Studies
  • Gene expression and cancer classification
  • Advanced Chemical Sensor Technologies
  • Pain Mechanisms and Treatments
  • Pain Management and Placebo Effect
  • Biochemical Analysis and Sensing Techniques
  • Metabolomics and Mass Spectrometry Studies

Jörn Lötsch's recent publications illustrate their contributions to artificial intelligence applications in biomedicine and pain research. Notable papers include:

  • Explainable Artificial Intelligence (XAI) in Biomedicine: Making AI Decisions Trustworthy for Physicians and Patients (2021), published in BioMedInformatics
  • Artificial intelligence and machine learning in pain research: a data scientometric analysis (2022), published in PAIN Reports

Frequent co-authors in their research collaborations include Alfred Ultsch, Dario Kringel, Thomas Hummel, Gerd Geißlinger, and Sebastian Malkusch.

Jörn Lötsch publishes regularly in several venues, with the highest number of contributions appearing in:

  • Research Square
  • International Journal of Molecular Sciences
  • Scientific Reports
  • BioMedInformatics
  • SSRN Electronic Journal

Best Publications

  • GTP cyclohydrolase and tetrahydrobiopterin regulate pain sensitivity and persistence

    Irmgard Tegeder;Michael Costigan;Robert S Griffin;Andrea Abele

  • Pharmacokinetics of codeine and its metabolite morphine in ultra-rapid metabolizers due to CYP2D6 duplication.

    J Kirchheiner;H Schmidt;M Tzvetkov;J-T H A Keulen

  • Ziconotide for treatment of severe chronic pain

    Achim Schmidtko;Jörn Lötsch;Rainer Freynhagen;Gerd Geisslinger

  • Pharmacokinetics of opioids in liver disease.

    Irmgard Tegeder;Jörn Lötsch;Gerd Geisslinger

  • Genetic predictors of the clinical response to opioid analgesics: Clinical utility and future perspectives

    Jörn Lötsch;Carsten Skarke;Jürgen Liefhold;Gerd Geisslinger

  • Importance of IL28B gene polymorphisms in hepatitis C virus genotype 2 and 3 infected patients.

    Christoph Sarrazin;Simone Susser;Alexandra Doehring;Christian Markus Lange

  • Ceramide synthases and ceramide levels are increased in breast cancer tissue

    Susanne Schiffmann;Jessica Sandner;Kerstin Birod;Ivonne Wobst

  • Meta-analysis of the relevance of the OPRM1 118A>G genetic variant for pain treatment.

    Carmen Walter;Jörn Lötsch

  • Pharmacokinetic–Pharmacodynamic Modeling of Opioids

    Jörn Lötsch

  • Analgesic effects of morphine and morphine-6-glucuronide in a transcutaneous electrical pain model in healthy volunteers

    Carsten Skarke;Jutta Darimont;Helmut Schmidt;Gerd Geisslinger

  • Clinical significance of results from olfactory testing.

    Volker Gudziol;Jörn Lötsch;Antje Hähner;Thomas Zahnert

  • Olfactory Function in Mild Cognitive Impairment and Alzheimer’s Disease: An Investigation Using Psychophysical and Electrophysiological Techniques

    Jürgen M. Peters;Thomas Hummel;Tilman Kratzsch;Jörn Lötsch

  • The polymorphism A118G of the human mu-opioid receptor gene decreases the pupil constrictory effect of morphine-6-glucuronide but not that of morphine

    Jörn Lötsch;Carsten Skarke;Sabine Grösch;Jutta Darimont

  • Machine learning in pain research.

    Jörn Lötsch;Alfred Ultsch

  • The μ-opioid receptor gene polymorphism 118A>G depletes alfentanil-induced analgesia and protects against respiratory depression in homozygous carriers

    Bruno G. Oertel;Ronald Schmidt;Andreas Schneider;Gerd Geisslinger

  • Are μ-opioid receptor polymorphisms important for clinical opioid therapy?

    Jörn Lötsch;Gerd Geisslinger

  • Does the A118G Polymorphism at the μ-opioid Receptor Gene Protect against Morphine-6-Glucuronide Toxicity?

    Jörn Lötsch;Michael Zimmermann;Jutta Darimont;Claudia Marx

  • Different odor tests contribute differently to the evaluation of olfactory loss.

    Jörn Lötsch;Heinz Reichmann;Thomas Hummel

  • Chronic opioid use is associated with increased DNA methylation correlating with increased clinical pain

    Alexandra Doehring;Bruno Georg Oertel;Reinhard Sittl;Jörn Lötsch

  • A Common Human μ-Opioid Receptor Genetic Variant Diminishes the Receptor Signaling Efficacy in Brain Regions Processing the Sensory Information of Pain

    Bruno Georg Oertel;Mattias Kettner;Klaus Scholich;Christoph Renné

Frequent Co-Authors

Gerd Geisslinger
Gerd Geisslinger Goethe University Frankfurt
Alfred Ultsch
Alfred Ultsch Philipp University of Marburg
Thomas Hummel
Thomas Hummel TU Dresden
Gerd Kobal
Gerd Kobal University of Erlangen-Nuremberg
Kay Brune
Kay Brune University of Erlangen-Nuremberg
Eija Kalso
Eija Kalso University of Helsinki
Christoph Sarrazin
Christoph Sarrazin Goethe University Frankfurt
Stefan Zeuzem
Stefan Zeuzem Goethe University Frankfurt
Rainer Freynhagen
Rainer Freynhagen Technical University of Munich
Steven Nordin
Steven Nordin Umeå University

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Related Online Degrees & Career Pathways

For students interested in medicine or healthcare careers in the USA, there are various online degree options and pathways to consider. Online programs offer a flexible way to expand your skills, prepare for advanced roles, or enter new areas of the health sector.

If you want to move into healthcare leadership, pursuing one of the most affordable mha programs can provide you with management expertise and open doors to administrative positions. For those aiming to become nurse leaders or advanced practitioners, exploring the cheapest dnp programs online could be a cost-effective route to a Doctor of Nursing Practice degree.

Pharmacists are in high demand, and accredited online pharmacy schools make it possible to earn a doctorate while balancing other life commitments. Additionally, students interested in the fast-growing medical data field should consider the best online schools for high school students offering health information management degrees, which prepare graduates for roles in healthcare technology, data analysis, and more.

Each pathway offers unique opportunities for career growth and specialization, allowing future healthcare professionals to tailor their education to their aspirations and lifestyle.

Best Scientists Citing Jörn Lötsch

Trending Scientists

Recently Published Articles