Carrie K. Jones

Overview

Best Publications

• Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia

  P. Jeffrey Conn;Craig W. Lindsley;Craig W. Lindsley;Carrie K. Jones

  415
  Citations

• Subtype-selective allosteric modulators of muscarinic receptors for the treatment of CNS disorders

  P. Jeffrey Conn;Carrie K. Jones;Craig W. Lindsley;Craig W. Lindsley

  320
  Citations

• Novel Selective Allosteric Activator of the M1 Muscarinic Acetylcholine Receptor Regulates Amyloid Processing and Produces Antipsychotic-Like Activity in Rats

  Carrie K. Jones;Ashley E. Brady;Albert A. Davis;Zixiu Xiang

  291
  Citations

• Muscarinic and nicotinic acetylcholine receptor agonists and allosteric modulators for the treatment of schizophrenia.

  Carrie K Jones;Nellie Byun;Michael Bubser

  257
  Citations

• Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity.

  Alice L. Rodriguez;Mark D. Grier;Carrie K. Jones;Elizabeth J. Herman

  241
  Citations

• Discovery, characterization, and antiparkinsonian effect of novel positive allosteric modulators of metabotropic glutamate receptor 4.

  Colleen M. Niswender;Kari A. Johnson;C. David Weaver;Carrie K. Jones

  238
  Citations

• Centrally Active Allosteric Potentiators of the M4 Muscarinic Acetylcholine Receptor Reverse Amphetamine-Induced Hyperlocomotor Activity in Rats

  Ashley E. Brady;Carrie K. Jones;Thomas M. Bridges;J. Phillip Kennedy

  226
  Citations

• The Role of Estrogen in Brain and Cognitive Aging

  Jason K Russell;Carrie K Jones;Paul A Newhouse

  208
  Citations

• Biphenyl-indanone A, a positive allosteric modulator of the metabotropic glutamate receptor subtype 2, has antipsychotic- and anxiolytic-like effects in mice.

  Ruggero Galici;Carrie K. Jones;Kamondanai Hemstapat;Yi Nong

  206
  Citations

• Efficacy of duloxetine, a potent and balanced serotonergic and noradrenergic reuptake inhibitor, in inflammatory and acute pain models in rodents.

  Carrie K. Jones;Steven C. Peters;Harlan E. Shannon

  195
  Citations

• Functional Impact of Allosteric Agonist Activity of Selective Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 in Regulating Central Nervous System Function

  Meredith J. Noetzel;Jerri M. Rook;Paige N. Vinson;Hyekyung P. Cho

  181
  Citations

• Selective Activation of M4 Muscarinic Acetylcholine Receptors Reverses MK-801-Induced Behavioral Impairments and Enhances Associative Learning in Rodents

  Michael Bubser;Thomas M Bridges;Thomas M Bridges;Ditte Dencker;Robert W Gould

  161
  Citations

• Antipsychotic-like Effects of M4 Positive Allosteric Modulators Are Mediated by CB2 Receptor-Dependent Inhibition of Dopamine Release

  Daniel J. Foster;Jermaine M. Wilson;Daniel H. Remke;M. Suhaib Mahmood

  153
  Citations

• A novel selective muscarinic acetylcholine receptor subtype 1 antagonist reduces seizures without impairing hippocampus-dependent learning.

  Douglas J. Sheffler;Richard Williams;Thomas M. Bridges;Zixiu Xiang

  145
  Citations

• Muscarinic Receptor Pharmacology and Circuitry for the Modulation of Cognition

  Michael Bubser;Nellie Byun;Michael R. Wood;Carrie K. Jones

  143
  Citations

• The Metabotropic Glutamate Receptor 4-Positive Allosteric Modulator VU0364770 Produces Efficacy Alone and in Combination with l-DOPA or an Adenosine 2A Antagonist in Preclinical Rodent Models of Parkinson's Disease

  Carrie K. Jones;Michael Bubser;Analisa D. Thompson;Jonathan W. Dickerson

  139
  Citations

• Biased mGlu5-positive allosteric modulators provide in vivo efficacy without potentiating mGlu5 modulation of NMDAR currents

  Jerri M. Rook;Zixiu Xiang;Xiaohui Lv;Ayan Ghoshal

  136
  Citations

• Discovery of the first highly M5-preferring muscarinic acetylcholine receptor ligand, an M5 positive allosteric modulator derived from a series of 5-trifluoromethoxy N-benzyl isatins.

  Thomas M. Bridges;Joy E. Marlo;Colleen M. Niswender;Carrie K. Jones

  135
  Citations

• Antipsychotic drug-like effects of the selective M4 muscarinic acetylcholine receptor positive allosteric modulator VU0152100.

  Nellie E Byun;Michael Grannan;Michael Bubser;Robert L Barry

  131
  Citations

• Muscarinic Cholinergic Modulation of Prepulse Inhibition of the Acoustic Startle Reflex

  Carrie K. Jones;Harlan E. Shannon

  128
  Citations

• Novel Allosteric Agonists of M1 Muscarinic Acetylcholine Receptors Induce Brain Region-Specific Responses That Correspond with Behavioral Effects in Animal Models

  G. J. Digby;M. J. Noetzel;M. Bubser;T. J. Utley

  127
  Citations