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Shaun R. Stauffer

Shaun R. Stauffer

Cleveland Clinic
United States

D-Index & Metrics

Chemistry

D-Index
42
Citations
6625
World Ranking
17511
National Ranking
4285

Shaun R. Stauffer publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where Shaun R. Stauffer sits on this spectrum.

61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61 publications 1,295+

This scientist: 113 publications — 4th percentile

4% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

Shaun R. Stauffer D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Shaun R. Stauffer sits on this spectrum.

40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40 D-Index 159+

This scientist: 42 D-Index — 3rd percentile

3% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

Overview

Shaun R. Stauffer is affiliated with the Cleveland Clinic in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, with significant contributions also in Medicine. Subfields of study include Molecular Biology, Immunology, Computational Theory and Mathematics, Oncology, and Pulmonary and Respiratory Medicine.

The scientist's main research topics cover areas such as Epigenetics and DNA Methylation, Computational Drug Discovery Methods, Prostate Cancer Treatment and Research, SARS-CoV-2 and COVID-19 Research, Receptor Mechanisms and Signaling, Protein Degradation and Inhibitors, and interferon and immune responses.

Recent published papers by Shaun R. Stauffer include:

  • Endophenotype-based in silico network medicine discovery combined with insurance record data mining identifies sildenafil as a candidate drug for Alzheimer's disease, 2021, Nature Aging
  • Structure-Based Optimization of ML300-Derived, Noncovalent Inhibitors Targeting the Severe Acute Respiratory Syndrome Coronavirus 3CL Protease (SARS-CoV-2 3CLpro), 2021, Journal of Medicinal Chemistry
  • Discovery of WD Repeat-Containing Protein 5 (WDR5)-MYC Inhibitors Using Fragment-Based Methods and Structure-Based Design, 2020, Journal of Medicinal Chemistry
  • WDR5 represents a therapeutically exploitable target for cancer stem cells in glioblastoma, 2023, Genes & Development
  • Small Molecule-Based Prodrug Targeting Prostate Specific Membrane Antigen for the Treatment of Prostate Cancer, 2021, Cancers

Frequent co-authors collaborating with Shaun R. Stauffer include Christopher M. Goins, Jesse A. Coker, Joseph Alvarado, Jonathan D. Macdonald, and Christopher G. Hubert.

Stauffer's work is published frequently in venues such as bioRxiv (Cold Spring Harbor Laboratory), Journal of Medicinal Chemistry, Cancer Research, Nature Aging, and Current Research in Pharmacology and Drug Discovery.

Best Publications

  • Pyrazole Ligands: Structure−Affinity/Activity Relationships and Estrogen Receptor-α-Selective Agonists

    Shaun R. Stauffer;Christopher J. Coletta;Rosanna Tedesco;Gisele Nishiguchi

  • High turnover number and rapid, room-temperature amination of chloroarenes using saturated carbene ligands.

    Shaun R. Stauffer;Sunwoo Lee;James P. Stambuli;Sheila I. Hauck

  • Novel structural templates for estrogen-receptor ligands and prospects for combinatorial synthesis of estrogens

    Brian E Fink;Deborah S Mortensen;Shaun R Stauffer;Zachary D Aron

  • Copper-facilitated Suzuki reactions: application to 2-heterocyclic boronates.

    James Z Deng;Daniel V Paone;Anthony T Ginnetti;Hideki Kurihara

  • Discovery, synthesis, and structure-based optimization of a series of N -(tert -Butyl)-2-(N -arylamido)-2-(pyridin-3-yl) acetamides (ML188) as potent noncovalent small molecule inhibitors of the severe acute respiratory syndrome coronavirus (SARS-CoV) 3CL protease

    Jon Jacobs;Valerie Grum-Tokars;Ya Zhou;Mark Turlington

  • Discovery of novel allosteric modulators of metabotropic glutamate receptor subtype 5 reveals chemical and functional diversity and in vivo activity in rat behavioral models of anxiolytic and antipsychotic activity.

    Alice L. Rodriguez;Mark D. Grier;Carrie K. Jones;Elizabeth J. Herman

  • Functional Impact of Allosteric Agonist Activity of Selective Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 in Regulating Central Nervous System Function

    Meredith J. Noetzel;Jerri M. Rook;Paige N. Vinson;Hyekyung P. Cho

  • Palladium-catalyzed arylation of ethyl cyanoacetate. Fluorescence resonance energy transfer as a tool for reaction discovery.

    Shaun R. Stauffer;Neil A. Beare;James P. Stambuli;John F. Hartwig

  • Advancing Biological Understanding and Therapeutics Discovery with Small Molecule Probes

    Stuart L. Schreiber;Stuart L. Schreiber;Joanne D. Kotz;Min Li;Min Li;Jeffrey Aubé

  • Fluorescence Resonance Energy Transfer (FRET) as a High-Throughput Assay for Coupling Reactions. Arylation of Amines as a Case Study

    Shaun R. Stauffer;John F. Hartwig

  • Discovery of N-(benzo[1,2,3]triazol-1-yl)-N-(benzyl)acetamido)phenyl) carboxamides as severe acute respiratory syndrome coronavirus (SARS-CoV) 3CLpro inhibitors: identification of ML300 and noncovalent nanomolar inhibitors with an induced-fit binding.

    Mark Turlington;Aspen Chun;Aspen Chun;Sakshi Tomar;Aimee Eggler

  • Estrogen pyrazoles: defining the pyrazole core structure and the orientation of substituents in the ligand binding pocket of the estrogen receptor.

    Shaun R Stauffer;Ying Huang;Christopher J Coletta;Rosanna Tedesco

  • Estrogen receptor ligands

    John A. Katzenellenbogen;Benita S. Katzenellenbogen;Brian E. Fink;Shaun R. Stauffer

  • First demonstration of cerebrospinal fluid and plasma A beta lowering with oral administration of a beta-site amyloid precursor protein-cleaving enzyme 1 inhibitor in nonhuman primates.

    Sethu Sankaranarayanan;Marie A. Holahan;Dennis Colussi;Ming-Chih Crouthamel

  • Triarylpyrazoles with basic side chains: development of pyrazole-based estrogen receptor antagonists.

    Shaun R Stauffer;Ying R Huang;Zachary D Aron;Christopher J Coletta

  • High-Affinity Small-Molecule Inhibitors of the Menin-Mixed Lineage Leukemia (MLL) Interaction Closely Mimic a Natural Protein–Protein Interaction

    Shihan He;Timothy J. Senter;Jonathan Pollock;Changho Han

  • Unique Signaling Profiles of Positive Allosteric Modulators of Metabotropic Glutamate Receptor Subtype 5 Determine Differences in In Vivo Activity

    Jerri M. Rook;Meredith J. Noetzel;Wendy A. Pouliot;Thomas M. Bridges

  • Potentiation of M1 Muscarinic Receptor Reverses Plasticity Deficits and Negative and Cognitive Symptoms in a Schizophrenia Mouse Model.

    A Ghoshal;J M Rook;J W Dickerson;G N Roop

  • Targeting zoonotic viruses: Structure-based inhibition of the 3C-like protease from bat coronavirus HKU4--The likely reservoir host to the human coronavirus that causes Middle East Respiratory Syndrome (MERS).

    Sarah E. St. John;Sakshi Tomar;Shaun R. Stauffer;Andrew D. Mesecar

  • Solid-Phase Synthesis of Tetrasubstituted Pyrazoles, Novel Ligands for the Estrogen Receptor

    Shaun R. Stauffer;John A. Katzenellenbogen

  • Investigating Metabotropic Glutamate Receptor 5 Allosteric Modulator Cooperativity, Affinity, and Agonism: Enriching Structure-Function Studies and Structure-Activity Relationships

    Karen J. Gregory;Meredith J. Noetzel;Jerri M. Rook;Paige N. Vinson

Frequent Co-Authors

Craig W. Lindsley
Craig W. Lindsley Vanderbilt University
P. Jeffrey Conn
P. Jeffrey Conn Vanderbilt University
Colleen M. Niswender
Colleen M. Niswender Vanderbilt University
Carrie K. Jones
Carrie K. Jones Vanderbilt University
C. David Weaver
C. David Weaver Vanderbilt University
Harold G. Selnick
Harold G. Selnick MSD (United States)
Joseph P. Vacca
Joseph P. Vacca MSD (United States)
Heidi E. Hamm
Heidi E. Hamm Vanderbilt University
John A. Katzenellenbogen
John A. Katzenellenbogen University of Illinois at Urbana-Champaign
John F. Hartwig
John F. Hartwig University of California, Berkeley

External Links

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Best Scientists Citing Shaun R. Stauffer

P. Jeffrey Conn

P. Jeffrey Conn

Vanderbilt University

Publications: 108

Craig W. Lindsley

Craig W. Lindsley

Vanderbilt University

Publications: 90

Colleen M. Niswender

Colleen M. Niswender

Vanderbilt University

Publications: 76

John A. Katzenellenbogen

John A. Katzenellenbogen

University of Illinois at Urbana-Champaign

Publications: 71

Benita S. Katzenellenbogen

Benita S. Katzenellenbogen

University of Illinois at Urbana-Champaign

Publications: 32

Kathryn E. Carlson

Kathryn E. Carlson

University of Illinois at Urbana-Champaign

Publications: 26

John F. Hartwig

John F. Hartwig

University of California, Berkeley

Publications: 26

Carrie K. Jones

Carrie K. Jones

Vanderbilt University

Publications: 24

Arthur Christopoulos

Arthur Christopoulos

Monash University

Publications: 22

Jean-Philippe Pin

Jean-Philippe Pin

University of Montpellier

Publications: 19

Cheryl H. Arrowsmith

Cheryl H. Arrowsmith

Structural Genomics Consortium

Publications: 16

Steven P. Nolan

Steven P. Nolan

Ghent University

Publications: 15

Hualiang Jiang

Hualiang Jiang

Chinese Academy of Sciences

Publications: 13

Arun K. Ghosh

Arun K. Ghosh

Purdue University West Lafayette

Publications: 13

Stephen L. Buchwald

Stephen L. Buchwald

MIT

Publications: 13

Andrew D. Mesecar

Andrew D. Mesecar

Purdue University West Lafayette

Publications: 13

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