D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 57 Citations 15,692 108 World Ranking 1970 National Ranking 66

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Cytokine

Hitoshi Kikutani mainly focuses on Semaphorin, Cell biology, Immunology, Receptor and T cell. His Semaphorin study combines topics from a wide range of disciplines, such as Axon guidance, Kinase and Immune system. His Cell biology research is multidisciplinary, relying on both Dendritic cell and Antigen-presenting cell.

Hitoshi Kikutani combines subjects such as Cancer research, Diabetic mouse and Function with his study of Immunology. His biological study spans a wide range of topics, including Molecular biology, Cytoplasm, Signal transduction and B cell. His T cell research incorporates themes from Cytotoxic T cell and Priming, Antigen.

His most cited work include:

  • Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1 (2122 citations)
  • Molecular cloning and structure of a pre-B-cell growth-stimulating factor (749 citations)
  • From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins (607 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Immunology, Molecular biology, Cell biology, Semaphorin and Receptor. His study ties his expertise on CD40 together with the subject of Immunology. His Molecular biology study incorporates themes from Cell culture, Gene, Cellular differentiation, B cell and Genetically modified mouse.

His Cell biology research integrates issues from T cell, Antigen-presenting cell, Dendritic cell, Biochemistry and Cellular immunity. His Semaphorin research includes themes of Axon guidance, Neuroscience, Nervous system and Immune system. His Receptor research is multidisciplinary, incorporating elements of Immunohistochemistry, Platelet, Thrombus and Signal transduction.

He most often published in these fields:

  • Immunology (37.66%)
  • Molecular biology (29.87%)
  • Cell biology (28.57%)

What were the highlights of his more recent work (between 2008-2017)?

  • Receptor (22.08%)
  • Immunology (37.66%)
  • Semaphorin (26.62%)

In recent papers he was focusing on the following fields of study:

His main research concerns Receptor, Immunology, Semaphorin, Molecular biology and Cell biology. His work deals with themes such as Endocrinology, Signal transduction, Thrombus and Nervous system, which intersect with Receptor. His Immunology study integrates concerns from other disciplines, such as Inhalation and Inhibitory postsynaptic potential.

His research in Semaphorin intersects with topics in Axon guidance, Neuroscience and Immune system. His research on Molecular biology also deals with topics like

  • Germinal center that intertwine with fields like CD40, breakpoint cluster region, Epstein–Barr virus, Plasma cell differentiation and Cancer research,
  • B-cell receptor which is related to area like CLEC7A, Lymphocyte, ZAP70, Immune receptor and Acquired immune system. His study in the fields of Myosin under the domain of Cell biology overlaps with other disciplines such as TLR7.

Between 2008 and 2017, his most popular works were:

  • Semaphorins guide the entry of dendritic cells into the lymphatics by activating myosin II (146 citations)
  • Immunological functions of the neuropilins and plexins as receptors for semaphorins (123 citations)
  • The CD100 Receptor Interacts with Its Plexin B2 Ligand to Regulate Epidermal γδ T Cell Function (117 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Cytokine

His scientific interests lie mostly in Semaphorin, Cell biology, Immune system, Receptor and Signal transduction. In the field of Cell biology, his study on GTPase overlaps with subjects such as Podosome. Immune system is a subfield of Immunology that Hitoshi Kikutani tackles.

His work in the fields of Neuroinflammation, Experimental autoimmune encephalomyelitis and Microglia overlaps with other areas such as Encephalomyelitis. His research integrates issues of Platelet, Thrombus and Hyperlipidemia in his study of Receptor. The Signal transduction study combines topics in areas such as SEMA3A, Function, Adoptive cell transfer, Neuroscience and Myosin.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

Takashi Nagasawa;Seiichi Hirota;Kazunobu Tachibana;Nobuyuki Takakura.
Nature (1996)

3468 Citations

Molecular cloning and structure of a pre-B-cell growth-stimulating factor

Takashi Nagasawa;Hitoshi Kikutani;Tadamitsu Kishimoto.
Proceedings of the National Academy of Sciences of the United States of America (1994)

1198 Citations

From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins

Anne-Sophie Korganow;Hong Ji;Sara Mangialaio;Véronique Duchatelle.
Immunity (1999)

958 Citations

Mimicry of CD40 Signals by Epstein-Barr Virus LMP1 in B Lymphocyte Responses

Junji Uchida;Teruhito Yasui;Yuko Takaoka-Shichijo;Masaaki Muraoka.
Science (1999)

562 Citations

Molecular structure of human lymphocyte receptor for immunoglobulin E

Hitoshi Kikutani;Seiji Inui;Ryoichi Sato;Edward L. Barsumian.
Cell (1986)

482 Citations

Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling.

Atsushi Kumanogoh;Chie Watanabe;Ihnsook Lee;Xiaosong Wang.
Immunity (2000)

480 Citations

Two species of human Fcε receptor II (FcεRIICD23): Tissue-specific and IL-4-specific regulation of gene expression

Akira Yokota;Hitoshi Kikutani;Tetsuji Tanaka;Ryoichi Sato.
Cell (1988)

457 Citations

Prevention of autoimmune insulitis by expression of I-E molecules in NOD mice

Hirofumi Nishimoto;Hitoshi Kikutani;Ken-ichi Yamamura;Tadamitsu Kishimoto.
Nature (1987)

425 Citations

Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2

Atsushi Kumanogoh;Satoko Marukawa;Kazuhiro Suzuki;Noriko Takegahara.
Nature (2002)

406 Citations

Semaphorins and their receptors in immune cell interactions

Kazuhiro Suzuki;Atsushi Kumanogoh;Hitoshi Kikutani.
Nature Immunology (2008)

391 Citations

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