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Hitoshi Kikutani

Hitoshi Kikutani

D-Index & Metrics

Immunology

D-Index
77
Citations
27980
World Ranking
1796
National Ranking
66

Overview

Hitoshi Kikutani is affiliated with Osaka University in Japan and has made contributions primarily in the fields of Medicine and Immunology and Microbiology. Their research spans various subfields including Immunology, Radiology, Nuclear Medicine and Imaging, Rheumatology, Physiology, and Epidemiology.

The scientist's work addresses several main topics, notably T-cell and B-cell Immunology, Monoclonal and Polyclonal Antibodies Research, Systemic Lupus Erythematosus Research, Autophagy in Disease and Therapy, Immune Cell Function and Interaction, Sinusitis and nasal conditions, and Allergic Rhinitis and Sensitization.

Recent publications by Hitoshi Kikutani include the following papers:

  • Anti-Double-Stranded DNA Antibodies Recognize DNA Presented on HLA Class II Molecules of Systemic Lupus Erythematosus Risk Alleles, 2021, Arthritis & Rheumatology
  • Local production of broadly cross-reactive IgE against multiple fungal cell wall polysaccharides in patients with allergic fungal rhinosinusitis, 2022, Allergy
  • Opposing roles of RUBCN isoforms in autophagy and memory B cell generation, 2023, Science Signaling
  • External stimulation induces the secretion of autophagosome-like vesicles by B cells, 2023, Autophagy Reports
  • Clonal landscape of autoantibody-secreting plasmablasts in COVID-19 patients, 2024, Life Science Alliance

The scientist has frequently published in venues such as International Immunology, Arthritis & Rheumatology, Allergy, Science Signaling, and Life Science Alliance.

Collaboration is a notable aspect of their work, with frequent co-authors including Shuhei Sakakibara, Chao-Yuan Tsai, Daisuke Okuzaki, Marwa Ali El Hussien, and Daisuke Motooka.

Best Publications

  • Defects of B-cell lymphopoiesis and bone-marrow myelopoiesis in mice lacking the CXC chemokine PBSF/SDF-1

    Takashi Nagasawa;Seiichi Hirota;Kazunobu Tachibana;Nobuyuki Takakura

  • The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation

    Tsutomu Kawabe;Tetsuji Naka;Kanji Yoshida;Takashi Tanaka

  • Molecular cloning and structure of a pre-B-cell growth-stimulating factor

    Takashi Nagasawa;Hitoshi Kikutani;Tadamitsu Kishimoto

  • From systemic T cell self-reactivity to organ-specific autoimmune disease via immunoglobulins

    Anne-Sophie Korganow;Hong Ji;Sara Mangialaio;Véronique Duchatelle

  • Mimicry of CD40 Signals by Epstein-Barr Virus LMP1 in B Lymphocyte Responses

    Junji Uchida;Teruhito Yasui;Yuko Takaoka-Shichijo;Masaaki Muraoka

  • Epstein-Barr virus nuclear antigen 2 specifically induces expression of the B-cell activation antigen CD23.

    F Wang;C D Gregory;M Rowe;A B Rickinson

  • Identification of CD72 as a lymphocyte receptor for the class IV semaphorin CD100: a novel mechanism for regulating B cell signaling.

    Atsushi Kumanogoh;Chie Watanabe;Ihnsook Lee;Xiaosong Wang

  • Molecular structure of human lymphocyte receptor for immunoglobulin E

    Hitoshi Kikutani;Seiji Inui;Ryoichi Sato;Edward L. Barsumian

  • Two species of human Fcε receptor II (FcεRIICD23): Tissue-specific and IL-4-specific regulation of gene expression

    Akira Yokota;Hitoshi Kikutani;Tetsuji Tanaka;Ryoichi Sato

  • Semaphorins and their receptors in immune cell interactions

    Kazuhiro Suzuki;Atsushi Kumanogoh;Hitoshi Kikutani

  • Class IV semaphorin Sema4A enhances T-cell activation and interacts with Tim-2

    Atsushi Kumanogoh;Satoko Marukawa;Kazuhiro Suzuki;Noriko Takegahara

  • CD40 ligand-transduced co-stimulation of T cells in the development of helper function

    Unknown

  • Prevention of autoimmune insulitis by expression of I-E molecules in NOD mice

    Hirofumi Nishimoto;Hitoshi Kikutani;Ken-ichi Yamamura;Tadamitsu Kishimoto

  • Protective Role of CD40 in Leishmania major Infection at Two Distinct Phases of Cell-Mediated Immunity

    Masahito Kamanaka;Philipp Yu;Teruhito Yasui;Kenji Yoshida

  • Dual roles of Sema6D in cardiac morphogenesis through region-specific association of its receptor, Plexin-A1, with off-track and vascular endothelial growth factor receptor type 2

    Toshihiko Toyofuku;Hong Zhang;Atsushi Kumanogoh;Noriko Takegahara

  • Semaphorin 7A initiates T-cell-mediated inflammatory responses through α1β1 integrin

    Kazuhiro Suzuki;Tatsusada Okuno;Midori Yamamoto;R. Jeroen Pasterkamp

  • The transmembrane semaphorin Sema4D/CD100, an inhibitor of axonal growth, is expressed on oligodendrocytes and upregulated after CNS lesion.

    Moreau-Fauvarque C;Kumanogoh A;Camand E;Jaillard C

  • The class IV semaphorin CD100 plays nonredundant roles in the immune system : defective B and T cell activation in CD100-deficient mice

    Wei Shi;Atsushi Kumanogoh;Chie Watanabe;Junji Uchida

  • Tumor angiogenesis and progression are enhanced by Sema4D produced by tumor-associated macrophages.

    Jose Rafael Sierra;Simona Corso;Luisa Caione;Virna Cepero

  • Accelerated tumor growth in mice deficient in DNAM-1 receptor.

    Akiko Iguchi-Manaka;Hirayasu Kai;Yumi Yamashita;Kai Shibata

  • Fc epsilon receptor, a specific differentiation marker transiently expressed on mature B cells before isotype switching.

    Hitoshi Kikutani;Masaki Suemura;Hajime Owaki;Hiroshige Nakamura

  • Aeroallergen-induced eosinophilic inflammation, lung damage, and airways hyperreactivity in mice can occur independently of IL-4 and allergen-specific immunoglobulins.

    S P Hogan;A Mould;H Kikutani;A J Ramsay

Frequent Co-Authors

Atsushi Kumanogoh
Atsushi Kumanogoh Osaka University
Tadamitsu Kishimoto
Tadamitsu Kishimoto Osaka University
Ken Ichi Yamamura
Ken Ichi Yamamura Kumamoto University
Nobuaki Yoshida
Nobuaki Yoshida University of Tokyo
Yuichi Yamamura
Yuichi Yamamura Osaka University
Ko Okumura
Ko Okumura Juntendo University
Toshio Hirano
Toshio Hirano National Institutes for Quantum and Radiological Science and Technology
Lawrence F. Brass
Lawrence F. Brass University of Pennsylvania
Shizuo Akira
Shizuo Akira Osaka University
Akira Shibuya
Akira Shibuya University of Tsukuba

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