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Microbiology

D-Index
58
Citations
14265
World Ranking
3393
National Ranking
1339

Overview

Raymond J. Pickles is affiliated with the University of North Carolina at Chapel Hill in the United States. Their primary field of study is Medicine, with a concentration on subfields including Epidemiology, Infectious Diseases, Pulmonary and Respiratory Medicine, Molecular Biology, and Immunology.

The scientist's research topics cover a broad range within respiratory and viral infections. Key areas include:

  • Respiratory viral infections research
  • SARS-CoV-2 and COVID-19 research
  • Neonatal respiratory health research
  • Virus-based gene therapy research
  • Influenza virus research studies
  • Viral gastroenteritis research and epidemiology
  • Tracheal and airway disorders

Among the recent publications associated with this researcher are:

  • "SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801," 2021, Nature
  • "Challenges and opportunities for antiviral monoclonal antibodies as COVID-19 therapy," 2020, Advanced Drug Delivery Reviews
  • "Thiol-based chemical probes exhibit antiviral activity against SARS-CoV-2 via allosteric disulfide disruption in the spike glycoprotein," 2022, Proceedings of the National Academy of Sciences
  • "Human T cells efficiently control RSV infection," 2023, JCI Insight
  • "Learning from past failures: Challenges with monoclonal antibody therapies for COVID-19," 2020, Journal of Controlled Release

Frequent co-authors working with this scientist include:

  • Ralph S. Baric
  • Richard C. Boucher
  • Scott H. Randell
  • Samuel K. Lai
  • Liqun Zhang

Publication venues that feature frequently in this scientist's work include:

  • UNC Libraries
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of Cystic Fibrosis
  • Proceedings of the National Academy of Sciences
  • Nature

Best Publications

  • The NLRP3 Inflammasome Mediates in vivo Innate Immunity to Influenza A Virus through Recognition of Viral RNA

    Irving C. Allen;Margaret A. Scull;Chris B. Moore;Eda K. Holl

  • The coxsackievirus and adenovirus receptor is a transmembrane component of the tight junction.

    Christopher J. Cohen;Joseph T.C. Shieh;Raymond J. Pickles;Takatsugu Okegawa

  • Respiratory Syncytial Virus Infection of Human Airway Epithelial Cells Is Polarized, Specific to Ciliated Cells, and without Obvious Cytopathology

    Liqun Zhang;Mark E. Peeples;Richard C. Boucher;Peter L. Collins

  • SARS-like WIV1-CoV poised for human emergence

    Vineet D. Menachery;Boyd L. Yount;Amy C Sims;Kari Debbink

  • Severe Acute Respiratory Syndrome Coronavirus Infection of Human Ciliated Airway Epithelia: Role of Ciliated Cells in Viral Spread in the Conducting Airways of the Lungs

    Amy C. Sims;Ralph S. Baric;Boyd Yount;Susan E. Burkett

  • Normal and Cystic Fibrosis Airway Surface Liquid Homeostasis THE EFFECTS OF PHASIC SHEAR STRESS AND VIRAL INFECTIONS

    Robert Tarran;Brian Button;Maryse Picher;Anthony M. Paradiso

  • NLRX1 Protein Attenuates Inflammatory Responses to Infection by Interfering with the RIG-I-MAVS and TRAF6-NF-κB Signaling Pathways

    Irving C. Allen;Chris B. Moore;Monika Schneider;Yu Lei

  • Inefficient gene transfer by adenovirus vector to cystic fibrosis airway epithelia of mice and humans

    Barbara R. Grubb;Raymond J. Pickles;Hong Ye;James R. Yankaskas

  • Characterization of exosome-like vesicles released from human tracheobronchial ciliated epithelium: a possible role in innate defense

    Mehmet Kesimer;Margaret Scull;Brian Brighton;Genevieve DeMaria

  • SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801.

    Angela Wahl;Lisa E. Gralinski;Claire E. Johnson;Wenbo Yao

  • Limited entry of adenovirus vectors into well-differentiated airway epithelium is responsible for inefficient gene transfer.

    Raymond J. Pickles;Douglas McCarty;Hirotoshi Matsui;Pádraig J. Hart

  • Infection of Ciliated Cells by Human Parainfluenza Virus Type 3 in an In Vitro Model of Human Airway Epithelium

    Liqun Zhang;Alexander Bukreyev;Catherine I. Thompson;Brandy Watson

  • Infection of human airway epithelium by human and avian strains of influenza a virus.

    Catherine I. Thompson;Wendy S. Barclay;Maria C. Zambon;Raymond J. Pickles

  • Synthetic recombinant bat SARS-like coronavirus is infectious in cultured cells and in mice.

    Michelle M. Becker;Rachel Lauren Graham;Eric F. Donaldson;Barry Rockx

  • Vaccine Efficacy in Senescent Mice Challenged with Recombinant SARS-CoV Bearing Epidemic and Zoonotic Spike Variants

    Damon Deming;Timothy Sheahan;Mark Heise;Boyd Yount

  • MAVS-mediated apoptosis and its inhibition by viral proteins.

    Yu Lei;Chris B. Moore;Rachael M. Liesman;Brian P. O'Connor

  • Tracheobronchial air-liquid interface cell culture: a model for innate mucosal defense of the upper airways?

    Mehmet Kesimer;Sara Kirkham;Raymond J. Pickles;Ashley G. Henderson

  • CFTR delivery to 25% of surface epithelial cells restores normal rates of mucus transport to human cystic fibrosis airway epithelium.

    Liqun Zhang;Brian Button;Sherif E. Gabriel;Susan Burkett

  • Molecular Organization of the Mucins and Glycocalyx Underlying Mucus Transport Over Mucosal Surfaces of the Airways

    M Kesimer;C Ehre;K A Burns;C W Davis

  • Retargeting the Coxsackievirus and Adenovirus Receptor to the Apical Surface of Polarized Epithelial Cells Reveals the Glycocalyx as a Barrier to Adenovirus-Mediated Gene Transfer

    Raymond J. Pickles;Jill A. Fahrner;JenniElizabeth M. Petrella;Richard C. Boucher

Frequent Co-Authors

Liqun Zhang
Liqun Zhang Xi'an Jiaotong University
Richard C. Boucher
Richard C. Boucher University of North Carolina at Chapel Hill
Ralph S. Baric
Ralph S. Baric University of North Carolina at Chapel Hill
Peter L. Collins
Peter L. Collins National Institutes of Health
Amy C. Sims
Amy C. Sims University of North Carolina at Chapel Hill
Eric F. Donaldson
Eric F. Donaldson Center for Drug Evaluation and Research
Mark E. Peeples
Mark E. Peeples The Ohio State University
Boyd Yount
Boyd Yount University of North Carolina at Chapel Hill
John C. Olsen
John C. Olsen University of North Carolina at Chapel Hill
Scott H. Randell
Scott H. Randell University of North Carolina at Chapel Hill

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