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Biology and Biochemistry

D-Index
48
Citations
10570
World Ranking
18281
National Ranking
7469

Overview

John C. Olsen is affiliated with the University of North Carolina at Chapel Hill in the United States. Their research spans several fields within biochemistry, genetics, molecular biology, and medicine. The main areas of study include molecular biology, genetics, pulmonary and respiratory medicine, plant science, and cell biology.

Their work covers multiple research topics such as virus-based gene therapy, chromosomal and genetic variations, neonatal respiratory health, tracheal and airway disorders, glycosylation and glycoproteins, RNA interference and gene delivery, and viral gastroenteritis research and epidemiology.

Recent publications by John C. Olsen include:

  • Secretory Cells Dominate Airway CFTR Expression and Function in Human Airway Superficial Epithelia, 2020, American Journal of Respiratory and Critical Care Medicine
  • Evidence Supporting a Zoonotic Origin of Human Coronavirus Strain NL63, 2020, UNC Libraries
  • Integrin alpha IIb promoter-targeted expression of gene products in megakaryocytes derived from retrovirus-transduced human hematopoietic cells, 2021, UNC Libraries
  • The Impact of Community Generated PPE During the SARS-COV-2 Pandemic in Southeast Alabama and Gulfport Mississippi, 2021, Frontiers in Health Services
  • Rearrangements in unintegrated retroviral DNA are complex and are the result of multiple genetic determinants., 2020, UNC Libraries

John C. Olsen frequently publishes in venues such as:

  • UNC Libraries, with 17 publications
  • American Journal of Respiratory and Critical Care Medicine
  • Frontiers in Health Services

Among frequent collaborators are Ronald Swanstrom, Richard C. Boucher, Barbara R. Grubb, Hong Dang, and Gianni Carraro.

John C. Olsen's scholarly contributions focus heavily on the interface of molecular mechanisms and respiratory medicine, with an emphasis on viral gene therapy and genetic variation research. Their investigations often explore the genetic determinants underlying respiratory function and viral interactions at the cellular level.

Best Publications

  • CFTR as a cAMP-dependent regulator of sodium channels.

    MJ Stutts;CM Canessa;JC Olsen;M Hamrick

  • A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis

    Michael R Knowles;Kathy W. Hohneker;Zhaoqing Zhou;John C. Olsen

  • Role of mutant CFTR in hypersusceptibility of cystic fibrosis patients to lung infections

    Gerald B. Pier;Martha Grout;Tanweer S. Zaidi;John C. Olsen

  • Cloning and expression of a human P2U nucleotide receptor, a target for cystic fibrosis pharmacotherapy.

    C E Parr;D M Sullivan;A M Paradiso;E R Lazarowski

  • Efficiency of gene transfer for restoration of normal airway epithelial function in cystic fibrosis

    Larry G. Johnson;John C. Olsen;Balazs Sarkadi;Karen L. Moore

  • A novel mutation in the cystic fibrosis gene in patients with pulmonary disease but normal sweat chloride concentrations

    W. Edward Highsmith;Lauranell H. Burch;Zhaoqing Zhou;John C. Olsen

  • Evidence Supporting a Zoonotic Origin of Human Coronavirus Strain NL63

    Jeremy Huynh;Shimena Li;Boyd Yount;Alexander Smith

  • Suppression of experimental arthritis by gene transfer of interleukin 1 receptor antagonist cDNA

    S S Makarov;J C Olsen;W N Johnston;S K Anderle

  • Gene transfer vectors derived from equine infectious anemia virus.

    JC Olsen

  • Induction of MHC class I expression by the MHC class II transactivator CIITA.

    Brian K. Martin;Keh Chuang Chin;John C. Olsen;Cheryl A. Skinner

  • Immortalization and transformation of primary human airway epithelial cells by gene transfer.

    Ante S Lundberg;Scott H Randell;Sheila A Stewart;Brian Elenbaas;Brian Elenbaas

  • A subset of mouse tracheal epithelial basal cells generates large colonies in vitro.

    Kelly G. Schoch;Adriana Lori;Kimberlie A. Burns;Tracy Eldred

  • SPLUNC1 regulates airway surface liquid volume by protecting ENaC from proteolytic cleavage

    Agustin Garcia-Caballero;Julia E. Rasmussen;Erol Gaillard;Michael J. Watson

  • Gene therapy for cystic fibrosis using E1-deleted adenovirus: a phase I trial in the nasal cavity. The University of North Carolina at Chapel Hill.

    Richard C Boucher;Michael R Knowles;Larry G. Johnson;John C. Olsen

  • Regulation of murine airway surface liquid volume by CFTR and Ca2+-activated Cl- conductances

    Robert Tarran;Matthew E. Loewen;Anthony M. Paradiso;John C. Olsen

  • Primary epithelial cell models for cystic fibrosis research.

    Scott H. Randell;M. Leslie Fulcher;Wanda O’Neal;John C. Olsen

  • Biochemical Characterization of a Recombinant TRIM5α Protein That Restricts Human Immunodeficiency Virus Type 1 Replication

    Charles R. Langelier;Virginie Sandrin;Debra M. Eckert;Devin E. Christensen

  • Immortal Activated Human Hepatic Stellate Cells Generated by Ectopic Telomerase Expression

    Bernd Schnabl;Youkyung Hwang Choi;John C Olsen;Curt H Hagedorn

  • The avian retrovirus env gene family: molecular analysis of host range and antigenic variants

    C A Bova;J C Olsen;R Swanstrom

  • Pseudotyped human lentiviral vector-mediated gene transfer to airway epithelia in vivo

    L G Johnson;J C Olsen;L Naldini;R C Boucher

Frequent Co-Authors

Richard C. Boucher
Richard C. Boucher University of North Carolina at Chapel Hill
Raymond J. Pickles
Raymond J. Pickles University of North Carolina at Chapel Hill
Ronald Swanstrom
Ronald Swanstrom University of North Carolina at Chapel Hill
Bruce A. Bunnell
Bruce A. Bunnell University of North Texas Health Science Center
Scott H. Randell
Scott H. Randell University of North Carolina at Chapel Hill
Robert Tarran
Robert Tarran University of North Carolina at Chapel Hill
Michael R. Knowles
Michael R. Knowles University of North Carolina at Chapel Hill
M. Jackson Stutts
M. Jackson Stutts University of North Carolina at Chapel Hill
Mark E. Peeples
Mark E. Peeples The Ohio State University
Liqun Zhang
Liqun Zhang Xi'an Jiaotong University

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