Michael R. Knowles focuses on Cystic fibrosis, Pathology, Internal medicine, Primary ciliary dyskinesia and Cystic fibrosis transmembrane conductance regulator. His research integrates issues of Sputum, Lung, Immunology and Amiloride in his study of Cystic fibrosis. In general Pathology study, his work on Respiratory epithelium often relates to the realm of Potential difference, thereby connecting several areas of interest.
His work deals with themes such as Gastroenterology, Endocrinology, Mucous membrane of nose and Transepithelial potential difference, which intersect with Internal medicine. His studies deal with areas such as Dynein, Cilium and Situs inversus as well as Primary ciliary dyskinesia. His studies in Cystic fibrosis transmembrane conductance regulator integrate themes in fields like Mutation, Genetic enhancement, Pancreatitis and Genotype.
Michael R. Knowles mainly investigates Cystic fibrosis, Primary ciliary dyskinesia, Internal medicine, Pathology and Genetics. His work on Cystic fibrosis transmembrane conductance regulator as part of general Cystic fibrosis research is frequently linked to Pancreatic disease, bridging the gap between disciplines. His Cystic fibrosis transmembrane conductance regulator study combines topics from a wide range of disciplines, such as Molecular biology and Genotype.
His Primary ciliary dyskinesia research is multidisciplinary, incorporating elements of Dynein, Cilium, Motile cilium and Situs inversus. His work in Internal medicine addresses issues such as Endocrinology, which are connected to fields such as Epithelium. His biological study spans a wide range of topics, including Airway, Respiratory system and Mucociliary clearance.
His primary areas of study are Primary ciliary dyskinesia, Internal medicine, Bronchiectasis, Cystic fibrosis and Cilium. The various areas that Michael R. Knowles examines in his Primary ciliary dyskinesia study include Cell biology, Mucociliary clearance, Motile cilium and Pathology. His Pathology research is multidisciplinary, relying on both Proteome, Low nasal nitric oxide, Situs inversus and Respiratory system.
His Internal medicine research focuses on Gastroenterology and how it connects with Airway, Liver transplantation and Case-control study. His Cystic fibrosis research incorporates elements of Genome-wide association study, Bioinformatics, Phenotype, Immunology and Lung disease. His work on Ciliogenesis is typically connected to Body movement as part of general Cilium study, connecting several disciplines of science.
Michael R. Knowles mainly investigates Primary ciliary dyskinesia, Internal medicine, Cystic fibrosis, Bronchiectasis and Cilium. The Primary ciliary dyskinesia study combines topics in areas such as Mucociliary clearance, Cohort study, Pathology and MEDLINE. His study in Pathology is interdisciplinary in nature, drawing from both Hypertonic saline, Inhalation and Respiratory system.
He has researched Internal medicine in several fields, including Type 1 diabetes and Type 2 diabetes. His Cystic fibrosis research is included under the broader classification of Genetics. His Cilium study combines topics in areas such as Obstructive lung disease, Gene, Compound heterozygosity and Ciliary Motility Disorders.
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Mucus clearance as a primary innate defense mechanism for mammalian airways
Michael R. Knowles;Richard C. Boucher.
Journal of Clinical Investigation (2002)
Relation between mutations of the cystic fibrosis gene and idiopathic pancreatitis.
Jonathan A. Cohn;Kenneth J. Friedman;Peadar G. Noone;Michael R. Knowles.
The New England Journal of Medicine (1998)
Primary ciliary dyskinesia: diagnostic and phenotypic features.
Peadar G Noone;Margaret W Leigh;Aruna Sannuti;Susan L. Minnix.
American Journal of Respiratory and Critical Care Medicine (2004)
Mucus clearance and lung function in cystic fibrosis with hypertonic saline.
Scott H. Donaldson;William D. Bennett;Kirby L. Zeman;Michael R. Knowles.
The New England Journal of Medicine (2006)
Consensus on the use and interpretation of cystic fibrosis mutation analysis in clinical practice
C. Castellani;H. Cuppens;M. Macek;J. J. Cassiman.
Journal of Cystic Fibrosis (2008)
Increased Bioelectric Potential Difference across Respiratory Epithelia in Cystic Fibrosis
Michael R Knowles;John Gatzy;Richard C Boucher.
The New England Journal of Medicine (1981)
A controlled study of adenoviral-vector-mediated gene transfer in the nasal epithelium of patients with cystic fibrosis
Michael R Knowles;Kathy W. Hohneker;Zhaoqing Zhou;John C. Olsen.
The New England Journal of Medicine (1995)
Na+ transport in cystic fibrosis respiratory epithelia. Abnormal basal rate and response to adenylate cyclase activation.
R C Boucher;M J Stutts;M R Knowles;L Cantley.
Journal of Clinical Investigation (1986)
Nontuberculous mycobacteria. I: multicenter prevalence study in cystic fibrosis.
Kenneth N. Olivier;David Jay Weber;Richard J. Wallace;Ali R. Faiz.
American Journal of Respiratory and Critical Care Medicine (2003)
Activation by extracellular nucleotides of chloride secretion in the airway epithelia of patients with cystic fibrosis.
Michael R. Knowles;Lane L. Clarke;Richard C. Boucher.
The New England Journal of Medicine (1991)
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