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Microbiology

D-Index
101
Citations
40872
World Ranking
384
National Ranking
21

Overview

Philippe Langella is a researcher affiliated with the University of Paris-Saclay in France. Their work focuses primarily on the interactions between gut microbiota and human health, with significant contributions in biochemistry, genetics, molecular biology, and medicine.

The researcher's publications span several key topics, including:

  • Gut microbiota and health
  • Probiotics and Fermented Foods
  • Clostridium difficile and Clostridium perfringens research
  • Microbial Metabolites in Food Biotechnology
  • Diet and metabolism studies
  • Infant Nutrition and Health
  • Gastrointestinal motility and disorders

The main fields of study covered in their work are Biochemistry, Genetics and Molecular Biology, and Medicine, with specific emphasis on molecular biology, food science, nutrition and dietetics, infectious diseases, and physiology.

Frequent publication venues for Langella include Microorganisms, bioRxiv (Cold Spring Harbor Laboratory), Gut Microbes, Scientific Reports, and Nutrients, reflecting a broad spectrum of microbiome-related research outputs.

Collaboration features prominently in Langella's career, with notable co-authors being Luis G. Bermúdez-Humarán, Rebeca Martín, Jean-Marc Chatel, Florian Chain, and Harry Sokol. Each has contributed to multiple joint publications advancing understanding in gut microbiota and related fields.

Selected recent publications highlight a focus on microbiota-derived molecules and their effects on human health:

  • Faecalibacterium: a bacterial genus with promising human health applications, 2023, FEMS Microbiology Reviews
  • Butyrate mediates anti-inflammatory effects of Faecalibacterium prausnitzii in intestinal epithelial cells through Dact3, 2020, Gut Microbes
  • Aryl hydrocarbon receptor ligand production by the gut microbiota is decreased in celiac disease leading to intestinal inflammation, 2020, Science Translational Medicine
  • The microbial metabolite p-Cresol induces autistic-like behaviors in mice by remodeling the gut microbiota, 2021, Microbiome
  • Possible Benefits of Faecalibacterium prausnitzii for Obesity-Associated Gut Disorders, 2021, Frontiers in Pharmacology

Best Publications

  • Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients

    Harry Sokol;Bénédicte Pigneur;Laurie Watterlot;Omar Lakhdari

  • CARD9 impacts colitis by altering gut microbiota metabolism of tryptophan into aryl hydrocarbon receptor ligands

    Bruno Lamas;Mathias L Richard;Valentin Leducq;Hang-Phuong Pham

  • Fungal microbiota dysbiosis in IBD

    Harry Sokol;Valentin Leducq;Hugues Aschard;Hang-Phuong Pham

  • Faecalibacterium prausnitzii and human intestinal health

    S. Miquel;R. Martin;R. Martin;O. Rossi;L.G. Bermudez-Humaran;L.G. Bermudez-Humaran

  • Microbial dysbiosis in colorectal cancer (CRC) patients.

    Iradj Sobhani;Julien Tap;Françoise Roudot-Thoraval;Jean P. Roperch

  • Connecting dysbiosis, bile-acid dysmetabolism and gut inflammation in inflammatory bowel diseases

    Henri Duboc;Sylvie Rajca;Sylvie Rajca;Dominique Rainteau;Dominique Rainteau;David Benarous

  • Intestinal mucosal adherence and translocation of commensal bacteria at the early onset of type 2 diabetes: molecular mechanisms and probiotic treatment

    Jacques Amar;Chantal Chabo;Aurelie Waget;Pascale Klopp

  • Beneficial effects on host energy metabolism of short-chain fatty acids and vitamins produced by commensal and probiotic bacteria

    Jean Guy LeBlanc;Florian Chain;Rebeca Martín;Luis G. Bermúdez-Humarán

  • Identification of an anti-inflammatory protein from Faecalibacterium prausnitzii, a commensal bacterium deficient in Crohn’s disease

    E. Quévrain;M.A. Maubert;C. Michon;F. Chain;F. Chain

  • Enterococcus hirae and Barnesiella intestinihominis Facilitate Cyclophosphamide-Induced Therapeutic Immunomodulatory Effects

    Romain Daillère;Romain Daillère;Romain Daillère;Marie Vétizou;Marie Vétizou;Marie Vétizou;Nadine Waldschmitt;Takahiro Yamazaki;Takahiro Yamazaki

  • Towards standards for human fecal sample processing in metagenomic studies

    Paul I. Costea;Georg Zeller;Shinichi Sunagawa;Eric Pelletier;Eric Pelletier

  • Two plasmid-determined restriction and modification systems in Streptococcus lactis.

    Alain Chopin;Marie-Christine Chopin;Agnès Moillo-Batt;Philippe Langella

  • Impaired Aryl Hydrocarbon Receptor Ligand Production by the Gut Microbiota Is a Key Factor in Metabolic Syndrome.

    Jane M. Natividad;Allison Agus;Julien Planchais;Bruno Lamas;Bruno Lamas

  • Faecalibacterium: a bacterial genus with promising human health applications

    Unknown

  • Functional Characterization of Novel Faecalibacterium prausnitzii Strains Isolated from Healthy Volunteers: A Step Forward in the Use of F. prausnitzii as a Next-Generation Probiotic.

    Rebeca Martín;Sylvie Miquel;Sylvie Miquel;Leandro Benevides;Leandro Benevides;Chantal Bridonneau

  • Faecal microbiota study reveals specific dysbiosis in spondyloarthritis

    Maxime Breban;Julien Tap;Ariane Leboime;Roula Said-Nahal

  • Emerging Health Concepts in the Probiotics Field: Streamlining the Definitions.

    Rebeca Martín;Philippe Langella

  • Fungal dysbiosis in mucosa-associated microbiota of Crohn’s disease patients

    Giuseppina Liguori;Bruno Lamas;Mathias L. Richard;Mathias L. Richard;Giovanni Brandi

  • Impairment of the Intestinal Barrier by Ethanol Involves Enteric Microflora and Mast Cell Activation in Rodents

    Laurent Ferrier;Florian Bérard;Laurent Debrauwer;Chantal Chabo

  • Faecalibacterium prausnitzii prevents physiological damages in a chronic low-grade inflammation murine model

    Rebeca Martín;Rebeca Martín;Rebeca Martín;Sylvie Miquel;Sylvie Miquel;Florian Chain;Florian Chain;Jane M Natividad

  • Role of commensal and probiotic bacteria in human health: a focus on inflammatory bowel disease

    Rebeca Martín;Rebeca Martín;Sylvie Miquel;Sylvie Miquel;Jonathan Ulmer;Jonathan Ulmer;Noura Kechaou;Noura Kechaou

  • Lactococci and lactobacilli as mucosal delivery vectors for therapeutic proteins and DNA vaccines.

    Luis G Bermúdez-Humarán;Pascale Kharrat;Jean-Marc Chatel;Philippe Langella

  • Lactococcus lactis, an Efficient Cell Factory for Recombinant Protein Production and Secretion

    E. Morello;L.G. Bermúdez-Humarán;D. Llull;V. Solé

Frequent Co-Authors

Luis G. Bermúdez-Humarán
Luis G. Bermúdez-Humarán University of Paris-Saclay
Harry Sokol
Harry Sokol Sorbonne University
Vasco Azevedo
Vasco Azevedo Universidade Federal de Minas Gerais
Anderson Miyoshi
Anderson Miyoshi Universidade Federal de Minas Gerais
Gérard Corthier
Gérard Corthier INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
Jean Guy LeBlanc
Jean Guy LeBlanc National Scientific and Technical Research Council
Yves Le Loir
Yves Le Loir INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
Alexandra Gruss
Alexandra Gruss INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
François Lefèvre
François Lefèvre INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement

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