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Biology and Biochemistry

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8328
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Overview

Alexandra Gruss is affiliated with INRAE, the Institut national de recherche pour l'agriculture, l'alimentation et l'environnement in France. Their research spans key areas within Medicine as well as Biochemistry, Genetics, and Molecular Biology, focusing extensively on infectious diseases and bacterial molecular processes.

Their work covers several subfields, including Infectious Diseases, Public Health, Environmental and Occupational Health, Molecular Biology, Genetics, and Food Science.

Among the primary topics explored in their publications are:

  • Antimicrobial Resistance in Staphylococcus
  • Streptococcal Infections and Treatments
  • Probiotics and Fermented Foods
  • Antibiotic Resistance in Bacteria
  • RNA and Protein Synthesis Mechanisms
  • Bacterial Genetics and Biotechnology
  • Bacterial Identification and Susceptibility Testing

Some of their recent papers include:

  • "FabT, a Bacterial Transcriptional Repressor That Limits Futile Fatty Acid Biosynthesis", 2022, Microbiology and Molecular Biology Reviews
  • "(p)ppGpp/GTP and Malonyl-CoA Modulate Staphylococcus aureus Adaptation to FASII Antibiotics and Provide a Basis for Synergistic Bi-Therapy", 2021, mBio
  • "Type II Fatty Acid Synthesis Pathway and Cyclopropane Ring Formation Are Dispensable during Enterococcus faecalis Systemic Infection", 2021, Journal of Bacteriology
  • "Do Primocolonizing Bacteria Enable Bacteroides thetaiotaomicron Intestinal Colonization Independently of the Capacity To Consume Oxygen?", 2021, mSphere
  • "Oxidative stress is intrinsic to staphylococcal adaptation to fatty acid synthesis antibiotics", 2024, iScience

They have published multiple articles in various venues, with several contributions found in bioRxiv (Cold Spring Harbor Laboratory), alongside publications in Microbiology and Molecular Biology Reviews, mBio, Journal of Bacteriology, and iScience.

Frequent collaborators in their work include:

  • Karine Gloux
  • David Halpern
  • Clara Lambert
  • Agnès Fouet
  • Paprapach Wongdontree

Best Publications

  • Regulation of exoprotein gene expression in Staphylococcus aureus by agr

    P. Recsei;B. Kreiswirth;M. O'Reilly;P. Schlievert

  • Efficient insertional mutagenesis in lactococci and other gram-positive bacteria.

    E Maguin;H Prévost;S D Ehrlich;A Gruss

  • High-efficiency gene inactivation and replacement system for gram-positive bacteria.

    Indranil Biswas;A. Gruss;S. D. Ehrlich;E. Maguin

  • The family of highly interrelated single-stranded deoxyribonucleic acid plasmids.

    A Gruss;S D Ehrlich

  • New thermosensitive plasmid for gram-positive bacteria.

    E Maguin;P Duwat;T Hege;D Ehrlich

  • Type II fatty acid synthesis is not a suitable antibiotic target for Gram-positive pathogens

    Sophie Brinster;Sophie Brinster;Gilles Lamberet;Bart Staels;Patrick Trieu-Cuot

  • Identification of the Bacterial Microflora in Dairy Products by Temporal Temperature Gradient Gel Electrophoresis

    Jean-Claude Ogier;Olivier Son;Alexandra Gruss;Patrick Tailliez

  • Raw Cow Milk Bacterial Population Shifts Attributable to Refrigeration

    Véronique Lafarge;Jean-Claude Ogier;Victoria Girard;Véronique Maladen

  • Respiration Capacity of the Fermenting Bacterium Lactococcus lactis and Its Positive Effects on Growth and Survival

    Patrick Duwat;Sophie Sourice;Bénédicte Cesselin;Gilles Lamberet

  • A Novel Mucosal Vaccine Based on Live Lactococci Expressing E7 Antigen and IL-12 Induces Systemic and Mucosal Immune Responses and Protects Mice against Human Papillomavirus Type 16-Induced Tumors

    Luis G. Bermúdez-Humarán;Naima G. Cortes-Perez;François Lefèvre;Valeria Guimarães

  • Acid- and multistress-resistant mutants of Lactococcus lactis : identification of intracellular stress signals.

    F Rallu;A Gruss;S D Ehrlich;E Maguin

  • HtrA is the unique surface housekeeping protease in Lactococcus lactis and is required for natural protein processing.

    Isabelle Poquet;Véronique Saint;Erwan Seznec;Nathalie Simoes

  • Production and Targeting of the Brucella abortus Antigen L7/L12 in Lactococcus lactis: a First Step towards Food-Grade Live Vaccines against Brucellosis

    Luciana A. Ribeiro;Luciana A. Ribeiro;Vasco Azevedo;Yves Le Loir;Sergio C. Oliveira

  • Bacterial swimmers that infiltrate and take over the biofilm matrix

    Ali Houry;Michel Gohar;Julien Deschamps;Ekaterina Tischenko

  • A Nine-Residue Synthetic Propeptide Enhances Secretion Efficiency of Heterologous Proteins in Lactococcus lactis

    Y. Le Loir;A. Gruss;S. D. Ehrlich;P. Langella

  • Design of a Protein-Targeting System for Lactic Acid Bacteria

    Y. Dieye;S. Usai;F. Clier;A. Gruss

  • Cloning, sequence, and expression of the lysostaphin gene from Staphylococcus simulans.

    Paul A. Recsei;Alexandra D. Gruss;Richard P. Novick

  • Aerobic Respiration Metabolism in Lactic Acid Bacteria and Uses in Biotechnology

    Martin B. Pedersen;Philippe Gaudu;Delphine Lechardeur;Marie Agnes Petit

  • Lactococcus lactis and stress.

    Fabien Rallu;Alexandra Gruss;Emmanuelle Maguin

  • Functional analysis of a palindromic sequence required for normal replication of several staphylococcal plasmids.

    Alexandra D. Gruss;Hope F. Ross;Richard P. Novick

Frequent Co-Authors

Yves Le Loir
Yves Le Loir INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
Luis G. Bermúdez-Humarán
Luis G. Bermúdez-Humarán University of Paris-Saclay
Philippe Langella
Philippe Langella University of Paris-Saclay
Richard P. Novick
Richard P. Novick New York University
Patrick Trieu-Cuot
Patrick Trieu-Cuot Institut Pasteur
Claire Poyart
Claire Poyart Institut Cochin
Vasco Azevedo
Vasco Azevedo Universidade Federal de Minas Gerais
Gérard Corthier
Gérard Corthier INRAE : Institut national de recherche pour l'agriculture, l'alimentation et l'environnement
S. Dusko Ehrlich
S. Dusko Ehrlich University College London
Romain Briandet
Romain Briandet University of Paris-Saclay

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