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Biology and Biochemistry

D-Index
78
Citations
25899
World Ranking
4488
National Ranking
2181

Overview

James P. Quigley is affiliated with the Scripps Research Institute in the United States. Their research activities primarily span the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with specific focus on Immunology and Allergy, Molecular Biology, Oncology, Immunology, and Epidemiology as subfields of study.

The scientist's work concentrates on topics including Cell Adhesion Molecules Research, Neutrophil, Myeloperoxidase and Oxidative Mechanisms, S100 Proteins and Annexins, Pancreatic and Hepatic Oncology Research, Cancer Cells and Metastasis, Neuroendocrine Tumor Research Advances, and Protease and Inhibitor Mechanisms.

Among the recent papers authored or co-authored by James P. Quigley are the following:

  • Neutrophil Elastase Facilitates Tumor Cell Intravasation and Early Metastatic Events, 2020, iScience
  • Effective targeting of intact and proteolysed CDCP1 for imaging and treatment of pancreatic ductal adenocarcinoma, 2020, Theranostics
  • Neutrophil Elastase Facilitates Cancer Cell Motility via Induction of Akt Signaling Pathway, 2020, The FASEB Journal
  • Self-assessment, 2022, Paediatrics and Child Health

Frequent collaborators in research include Elena I. Deryugina, Veronica C. Ardi, Alexia Carré, Tomoki Muramatsu, and Jonas Damgård Schmidt.

Publications of James P. Quigley have appeared in journals such as iScience, Theranostics, The FASEB Journal, and Paediatrics and Child Health, with contributions distributed mostly across these venues.

Best Publications

  • Matrix metalloproteinases and tumor metastasis

    Elena I. Deryugina;James P. Quigley

  • Localization of Matrix Metalloproteinase MMP-2 to the Surface of Invasive Cells by Interaction with Integrin αvβ3

    Peter C Brooks;Staffan Strömblad;Luraynne C Sanders;Tami L von Schalscha

  • Matrix metalloproteinase-2 is an interstitial collagenase. Inhibitor-free enzyme catalyzes the cleavage of collagen fibrils and soluble native type I collagen generating the specific 3/4- and 1/4-length fragments.

    Ronald T. Aimes;James P. Quigley

  • An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. I. Chick embryo fibroblast cultures transformed by avian RNA tumor viruses.

    J. C. Unkeless;A. Tobia;L. Ossowski;J. P. Quigley

  • Activation of Matrix Metalloproteinase-9 (MMP-9) via a Converging Plasmin/Stromelysin-1 Cascade Enhances Tumor Cell Invasion

    Noemi Ramos-DeSimone;Elizabeth Hahn-Dantona;John Sipley;Hideaki Nagase

  • Human neutrophils uniquely release TIMP-free MMP-9 to provide a potent catalytic stimulator of angiogenesis.

    Veronica C. Ardi;Tatyana A. Kupriyanova;Elena I. Deryugina;James P. Quigley

  • An enzymatic function associated with transformation of fibroblasts by oncogenic viruses. II. Mammalian fibroblast cultures transformed by DNA and RNA tumor viruses.

    L. Ossowski;J. C. Unkeless;A. Tobia;J. P. Quigley

  • Tumor angiogenesis: MMP-mediated induction of intravasation- and metastasis-sustaining neovasculature.

    Elena I. Deryugina;James P. Quigley

  • Type II transmembrane serine proteases. Insights into an emerging class of cell surface proteolytic enzymes

    John D. Hooper;Judith A. Clements;James P. Quigley;Toni M. Antalis

  • Distribution of (Na+-K+-stimulated ATPase activity in rat intestinal mucosa

    James P. Quigley;Gerald S. Gotterer

  • Viral nanoparticles as tools for intravital vascular imaging.

    John D Lewis;Giuseppe Destito;Giuseppe Destito;Andries Zijlstra;Maria J Gonzalez

  • Interleukin-1 beta regulates human cytotrophoblast metalloproteinase activity and invasion in vitro.

    C. L. Librach;S. L. Feigenbaum;K. E. Bass;Tian-Yi Cui

  • Alpha2-macroglobulin: an evolutionarily conserved arm of the innate immune system.

    Peter B Armstrong;James P Quigley

  • Tumor-Recruited Neutrophils and Neutrophil TIMP-Free MMP-9 Regulate Coordinately the Levels of Tumor Angiogenesis and Efficiency of Malignant Cell Intravasation

    Erin M. Bekes;Bernhard Schweighofer;Tatyana A. Kupriyanova;Ewa Zajac

  • Membrane anchored serine proteases: a rapidly expanding group of cell surface proteolytic enzymes with potential roles in cancer.

    Sarah Netzel-Arnett;John D. Hooper;Roman Szabo;Edwin L. Madison

  • Type IV collagenase(s) and TIMPs modulate endothelial cell morphogenesis in vitro

    H. William Schnaper;H. William Schnaper;Derrick S. Grant;William G. Stetler-Stevenson;Rafael Fridman

  • FIBRINOLYSIS ASSOCIATED WITH ONCOGENIC TRANSFORMATION : REQUIREMENT OF PLASMINOGEN FOR CORRELATED CHANGES IN CELLULAR MORPHOLOGY, COLONY FORMATION IN AGAR, AND CELL MIGRATION

    L. Ossowski;J. P. Quigley;G. M. Kellerman;E. Reich

  • Chick embryo chorioallantoic membrane model systems to study and visualize human tumor cell metastasis.

    Elena I. Deryugina;James P. Quigley

  • Tissue-infiltrating neutrophils constitute the major in vivo source of angiogenesis-inducing MMP-9 in the tumor microenvironment.

    Elena I. Deryugina;Ewa Zajac;Anna Juncker-Jensen;Tatyana A. Kupriyanova

  • Pleiotropic Roles of Matrix Metalloproteinases in Tumor Angiogenesis: Contrasting, Overlapping and Compensatory Functions

    Elena I. Deryugina;James P. Quigley

Frequent Co-Authors

Elena I. Deryugina
Elena I. Deryugina Scripps Research Institute
Daniel B. Rifkin
Daniel B. Rifkin New York University
Deborah L. French
Deborah L. French Children's Hospital of Philadelphia
Peter A. Andreasen
Peter A. Andreasen Aarhus University
Lars Sottrup-Jensen
Lars Sottrup-Jensen Aarhus University
Zaverio M. Ruggeri
Zaverio M. Ruggeri Scripps Research Institute
Walter Troll
Walter Troll New York University
Philippe E. Van den Steen
Philippe E. Van den Steen Rega Institute for Medical Research
Ghislain Opdenakker
Ghislain Opdenakker Rega Institute for Medical Research
Bruce E. Torbett
Bruce E. Torbett Seattle Children's Hospital

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