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Biology and Biochemistry

D-Index
107
Citations
50562
World Ranking
1085
National Ranking
653

Overview

William A. Haseltine is affiliated with Human Genome Sciences in the United States. Their research primarily spans the fields of Medicine and Biochemistry, Genetics and Molecular Biology, with notable focus on Molecular Biology, Infectious Diseases, Animal Science and Zoology, Epidemiology, and Genetics.

The scientist's main topics of work include SARS-CoV-2 and COVID-19 Research, Animal Virus Infections Studies, RNA and protein synthesis mechanisms, RNA modifications and cancer, Viral gastroenteritis research and epidemiology, Virus-based gene therapy research, and RNA Research and Splicing.

Haseltine has published several recent papers, including:

  • Experimental encephalomyelitis at age 90, still relevant and elucidating how viruses trigger disease (2023), published in The Journal of Experimental Medicine
  • The RNA Revolution in the Central Molecular Biology Dogma Evolution (2024), published in International Journal of Molecular Sciences
  • Intragenomic rearrangements involving 5'-untranslated region segments in SARS-CoV-2, other betacoronaviruses, and alphacoronaviruses (2023), published in Virology Journal
  • Universal Disease Screening and Treatment - The Egyptian Example (2020), published in New England Journal of Medicine
  • RNA Structure: Past, Future, and Gene Therapy Applications (2024), published in International Journal of Molecular Sciences

Frequent co-authors collaborating with Haseltine include Roberto Patarca, Kim Hazel, Lawrence Steinman, Ron Cohen, and Cedric Francois.

The scientist has contributed to multiple publication venues, with the most frequent being Preprints.org, International Journal of Molecular Sciences, Inside Precision Medicine, Genetic Engineering & Biotechnology News, and bioRxiv (Cold Spring Harbor Laboratory).

Best Publications

  • Complete nucleotide sequence of the AIDS virus, HTLV-III

    Lee Ratner;William Haseltine;Roberto Patarca;Kenneth J. Livak

  • Mutation of a mutL homolog in hereditary colon cancer

    Nickolas Papadopoulos;Nicholas C. Nicolaides;Ying Fei Wei;Steven M. Ruben

  • Mutations of two PMS homologues in hereditary nonpolyposis colon cancer.

    Nicholas C. Nicolaides;Nickolas Papadopoulos;Bo Liu;Ying Fei Weit

  • Functional regions of the envelope glycoprotein of human immunodeficiency virus type 1

    Mark Kowalski;Joseph Potz;Ladan Basiripour;Tatyana Dorfman

  • Role of capsid precursor processing and myristoylation in morphogenesis and infectivity of human immunodeficiency virus type 1

    Heinrich G. Gottlinger;Joseph G. Sodroski;William A. Haseltine

  • Role of the HTLV-III/LAV envelope in syncytium formation and cytopathicity.

    Joseph Sodroski;Wei Chun Goh;Craig Rosen;Kathryn Campbell

  • The location of cis-acting regulatory sequences in the human T cell lymphotropic virus type III (HTLV-III/LAV) long terminal repeat.

    Craig A. Rosen;Joseph G. Sodroski;William A. Haseltine

  • Trans-Acting Transcriptional Activation of the Long Terminal Repeat of Human T Lymphotropic Viruses in Infected Cells

    Joseph G. Sodroski;Craig A. Rosen;William A. Haseltine

  • Effect of mutations affecting the p6 gag protein on human immunodeficiency virus particle release.

    Heinrich G. Gottlinger;Tatyana Dorfman;Joseph G. Sodroski;William A. Haseltine

  • A second post-transcriptional trans -activator gene required for HTLV-III replication

    Joseph Sodroski;Wei Chun Goh;Craig Rosen;Andrew Dayton

  • Major glycoprotein antigens that induce antibodies in AIDS patients are encoded by HTLV-III

    JS Allan;JE Coligan;F Barin;MF McLane

  • The trans-activator gene of the human T cell lymphotropic virus type III is required for replication

    Andrew I. Dayton;Joseph G. Sodroski;Craig A. Rosen;Wei Chun Goh

  • Location of the trans-activating region on the genome of human T-cell lymphotropic virus type III.

    Joseph Sodroski;Roberto Patarca;Craig Rosen;Flossie Wong-Staal

  • Trans-acting transcriptional regulation of human T-cell leukemia virus type III long terminal repeat.

    J Sodroski;C Rosen;F Wong-Staal;SZ Salahuddin

  • Synthesis of Guanosine Tetra- and Pentaphosphate Requires the Presence of a Codon-Specific, Uncharged Transfer Ribonucleic Acid in the Acceptor Site of Ribosomes

    William A. Haseltine;Ricardo Block

  • Structural and functional characterization of human immunodeficiency virus tat protein.

    S Ruben;A Perkins;R Purcell;K Joung

  • Role of vif in replication of human immunodeficiency virus type 1 in CD4+ T lymphocytes.

    D H Gabuzda;K Lawrence;E Langhoff;E Terwilliger

  • Identification of individual human immunodeficiency virus type 1 gp120 amino acids important for CD4 receptor binding.

    U Olshevsky;E Helseth;C Furman;J Li

  • Human immunodeficiency virus vpr product is a virion-associated regulatory protein.

    E. A. Cohen;Ghassan Dehni;J. G. Sodroski;W. A. Haseltine

  • Identification of a sequence required for efficient packaging of human immunodeficiency virus type 1 RNA into virions.

    A Lever;H Gottlinger;W Haseltine;J Sodroski

Frequent Co-Authors

Joseph Sodroski
Joseph Sodroski Harvard Medical School
Craig A. Rosen
Craig A. Rosen CoGenesys, Inc.
Éric A. Cohen
Éric A. Cohen University of Montreal
Heinrich G. Göttlinger
Heinrich G. Göttlinger University of Massachusetts Chan Medical School
Douglas E. Brash
Douglas E. Brash Yale University
Myron Essex
Myron Essex Harvard University
Flossie Wong-Staal
Flossie Wong-Staal University of California, San Diego
David Baltimore
David Baltimore California Institute of Technology
Andrew M. L. Lever
Andrew M. L. Lever University of Cambridge
John M. Coffin
John M. Coffin Tufts University

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