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Immunology

D-Index
76
Citations
22262
World Ranking
1905
National Ranking
929

Overview

Wayne A. Marasco is affiliated with Harvard University in the United States and specializes primarily in the field of Medicine. Their research spans multiple subfields including Oncology, Immunology, Molecular Biology, Infectious Diseases, and Radiology, Nuclear Medicine and Imaging.

Their main topics of research encompass:

  • CAR-T cell therapy research
  • Monoclonal and Polyclonal Antibodies Research
  • SARS-CoV-2 and COVID-19 Research
  • Immune Cell Function and Interaction
  • T-cell and B-cell Immunology
  • Immunotherapy and Immune Responses
  • Renal and related cancers

Frequent co-authors collaborating with Wayne A. Marasco include:

  • Yufei Wang
  • Matthew Chang
  • Quan Zhu
  • Sabina Signoretti
  • Gordon J. Freeman

Their publications frequently appear in the following venues:

  • UNC Libraries
  • Cancer Research
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Regular and Young Investigator Award Abstracts

Notable recent papers include:

  • Ultra-Sensitive Serial Profiling of SARS-CoV-2 Antigens and Antibodies in Plasma to Understand Disease Progression in COVID-19 Patients with Severe Disease, 2020, Clinical Chemistry
  • A Novel Framework for Characterizing Genomic Haplotype Diversity in the Human Immunoglobulin Heavy Chain Locus, 2020, Frontiers in Immunology
  • Genetic variation in the immunoglobulin heavy chain locus shapes the human antibody repertoire, 2023, Nature Communications
  • A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence, 2020, UNC Libraries
  • Evolution of cell therapy for renal cell carcinoma, 2024, Molecular Cancer

Their research encompasses detailed studies on antibody repertoire genetics, immune cell interactions, and the progression of infectious diseases, notably COVID-19. They have contributed significantly to understanding genomic diversity within the immunoglobulin heavy chain locus and have been involved in advancing cell therapy approaches for oncology, particularly renal cell carcinoma.

Best Publications

  • Structural and Functional Bases for Broad-Spectrum Neutralization of Avian and Human Influenza A Viruses

    Jianhua Sui;William C Hwang;Sandra Elizabeth Pérez;Ge Wei

  • Antibody mediated in vivo delivery of small interfering RNAs via cell-surface receptors

    Erwei Song;Pengcheng Zhu;Sang Kyung Lee;Dipanjan Chowdhury

  • Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2

    Wenhui Li;Chengsheng Zhang;Chengsheng Zhang;Jianhua Sui;Jens H Kuhn;Jens H Kuhn

  • A SARS-like cluster of circulating bat coronaviruses shows potential for human emergence

    Vineet D. Menachery;Boyd L. Yount;Kari Debbink;Sudhakar Agnihothram

  • Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

    Jens Wrammert;Dimitrios G. Koutsonanos;Gui-Mei Li;Srilatha Edupuganti

  • Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association

    Jianhua Sui;Wenhui Li;Akikazu Murakami;Azaibi Tamin

  • SARS-like WIV1-CoV poised for human emergence

    Vineet D. Menachery;Boyd L. Yount;Amy C Sims;Kari Debbink

  • Design, intracellular expression, and activity of a human anti-human immunodeficiency virus type 1 gp120 single-chain antibody

    Wayne A. Marasco;William A. Haseltine;Siyi Chen

  • Broadly cross-reactive antibodies dominate the human B cell response against 2009 pandemic H1N1 influenza virus infection

    Unknown

  • The growth and potential of human antiviral monoclonal antibody therapeutics

    Wayne A Marasco;Jianhua Sui

  • Chimeric antigen receptor T cells secreting anti-PD-L1 antibodies more effectively regress renal cell carcinoma in a humanized mouse model.

    Eloah Rabello Suarez;De Kuan Chang;Jiusong Sun;Jianhua Sui

  • Method of intracellular binding of target molecules

    Wayne A. Marasco;William A. Haseltine

  • Crystal Structure of West Nile Virus Envelope Glycoprotein Reveals Viral Surface Epitopes

    Ryuta Kanai;Kalipada Kar;Karen Anthony;L. Hannah Gould

  • Identification of human neutralizing antibodies against MERS-CoV and their role in virus adaptive evolution

    Xian Chun Tang;Sudhakar S. Agnihothram;Yongjun Jiao;Jeremy Stanhope

  • Human Coronavirus HKU1 Spike Protein Uses O-Acetylated Sialic Acid as an Attachment Receptor Determinant and Employs Hemagglutinin-Esterase Protein as a Receptor-Destroying Enzyme

    Xingchuan Huang;Wenjuan Dong;Aleksandra Milewska;Anna Golda

  • Inhibition of HIV-1 Tat-mediated LTR transactivation and HIV-1 infection by anti-Tat single chain intrabodies.

    A.M. Mhashilkar;J. Bagley;S.Y. Chen;A.M. Szilvay

  • Structural Basis of Neutralization by a Human Anti-severe Acute Respiratory Syndrome Spike Protein Antibody, 80R

    William C. Hwang;Yaqiong Lin;Eugenio Santelli;Jianhua Sui

  • A mouse model for MERS coronavirus-induced acute respiratory distress syndrome

    Adam S. Cockrell;Boyd L. Yount;Trevor Scobey;Kara Jensen

  • Substance P binds to the formylpeptide chemotaxis receptor on the rabbit neutrophil.

    W.A. Marasco;H.J. Showell;E.L. Becker

  • Intrabodies: turning the humoral immune system outside in for intracellular immunization.

    Marasco Wa

  • The S proteins of human coronavirus NL63 and severe acute respiratory syndrome coronavirus bind overlapping regions of ACE2.

    Wenhui Li;Jianhua Sui;I-Chueh Huang;Jens H. Kuhn;Jens H. Kuhn

Frequent Co-Authors

Joseph Sodroski
Joseph Sodroski Harvard Medical School
Peter A. Ward
Peter A. Ward University of Michigan–Ann Arbor
Michael Farzan
Michael Farzan Harvard Medical School
Ralph S. Baric
Ralph S. Baric University of North Carolina at Chapel Hill
Robert C. Liddington
Robert C. Liddington Discovery Institute
David R. Walt
David R. Walt Harvard University
Wenhui Li
Wenhui Li Tsinghua University
Vineet D. Menachery
Vineet D. Menachery The University of Texas Medical Branch at Galveston
Boyd Yount
Boyd Yount University of North Carolina at Chapel Hill
Sabina Signoretti
Sabina Signoretti Brigham and Women's Hospital

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