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Immunology

D-Index
98
Citations
56222
World Ranking
768
National Ranking
437

Overview

Michael Farzan is affiliated with Harvard Medical School in the United States. Their research primarily focuses on the fields of Medicine, with significant work in Infectious Diseases, Molecular Biology, Immunology, Animal Science and Zoology, and Virology.

The scientist's work covers several key topics including:

  • SARS-CoV-2 and COVID-19 Research
  • COVID-19 Clinical Research Studies
  • Animal Virus Infections Studies
  • HIV Research and Treatment
  • Monoclonal and Polyclonal Antibodies Research
  • Viral gastroenteritis research and epidemiology
  • Immune Cell Function and Interaction

Michael Farzan has published extensively, with notable recent papers including:

  • "Mechanisms of SARS-CoV-2 entry into cells," 2021, published in Nature Reviews Molecular Cell Biology
  • "SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues," 2020, published in Cell
  • "SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity," 2020, published in Nature Communications
  • "The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity," 2020, published in bioRxiv (Cold Spring Harbor Laboratory)
  • "A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice," 2020, published in Immunity

The scientist collaborates frequently with several co-authors, including:

  • Hyeryun Choe
  • Lizhou Zhang
  • Huihui Mou
  • Brian D. Quinlan
  • Wenhui He

Michael Farzan's publications appear regularly in a variety of venues. Frequent publication journals and platforms include:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • SLAS DISCOVERY
  • Nature
  • Nature Communications
  • Immunity

Best Publications

  • Angiotensin-converting enzyme 2 is a functional receptor for the SARS coronavirus.

    Wenhui Li;Michael J. Moore;Natalya Vasilieva;Jianhua Sui

  • The β-Chemokine Receptors CCR3 and CCR5 Facilitate Infection by Primary HIV-1 Isolates

    Hyeryun Choe;Michael Farzan;Ying Sun;Nancy Sullivan

  • Mechanisms of SARS-CoV-2 entry into cells.

    Cody B Jackson;Cody B Jackson;Michael Farzan;Bing Chen;Bing Chen;Hyeryun Choe

  • The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry.

    Conrad C. Bleul;Michael Farzan;Hyeryun Choe;Cristina Parolin;Cristina Parolin

  • SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues.

    Carly G.K. Ziegler;Samuel J. Allon;Sarah K. Nyquist;Ian M. Mbano

  • Structure of SARS Coronavirus Spike Receptor-Binding Domain Complexed with Receptor

    Fang Li;Wenhui Li;Wenhui Li;Michael Farzan;Michael Farzan;Stephen C. Harrison;Stephen C. Harrison

  • The IFITM Proteins Mediate Cellular Resistance to Influenza A H1N1 Virus, West Nile Virus, and Dengue Virus

    Abraham L. Brass;Abraham L. Brass;Abraham L. Brass;I-Chueh Huang;Yair Benita;Sinu P. John

  • CCR3 and CCR5 are co-receptors for HIV-1 infection of microglia

    Jianglin He;Youzhi Chen;Michael Farzan;Hyeryun Choe

  • Receptor and viral determinants of SARS-coronavirus adaptation to human ACE2

    Wenhui Li;Chengsheng Zhang;Chengsheng Zhang;Jianhua Sui;Jens H Kuhn;Jens H Kuhn

  • ACE2 Receptor Expression and Severe Acute Respiratory Syndrome Coronavirus Infection Depend on Differentiation of Human Airway Epithelia

    Hong Peng Jia;Dwight C. Look;Lei Shi;Melissa Hickey

  • Influenza A Virus NS1 Targets the Ubiquitin Ligase TRIM25 to Evade Recognition by the Host Viral RNA Sensor RIG-I

    Michaela Ulrike Gack;Randy Allen Albrecht;Tomohiko Urano;Tomohiko Urano;Kyung-Soo Inn;Kyung-Soo Inn

  • The broad-spectrum antiviral functions of IFIT and IFITM proteins

    Michael S. Diamond;Michael Farzan

  • SARS-CoV-2 spike-protein D614G mutation increases virion spike density and infectivity

    Lizhou Zhang;Cody B. Jackson;Huihui Mou;Amrita Ojha

  • A 193-Amino Acid Fragment of the SARS Coronavirus S Protein Efficiently Binds Angiotensin-converting Enzyme 2

    Swee Kee Wong;Wenhui Li;Michael J. Moore;Hyeryun Choe

  • Tyrosine Sulfation of the Amino Terminus of CCR5 Facilitates HIV-1 Entry

    Michael Farzan;Tajib Mirzabekov;Peter Kolchinsky;Richard Wyatt

  • The D614G mutation in the SARS-CoV-2 spike protein reduces S1 shedding and increases infectivity

    Lizhou Zhang;Cody B Jackson;Huihui Mou;Amrita Ojha

  • Distinct patterns of IFITM-mediated restriction of filoviruses, SARS coronavirus, and influenza A virus.

    I-Chueh Huang;Charles C. Bailey;Jessica L. Weyer;Sheli R. Radoshitzky

  • Potent neutralization of severe acute respiratory syndrome (SARS) coronavirus by a human mAb to S1 protein that blocks receptor association

    Jianhua Sui;Wenhui Li;Akikazu Murakami;Azaibi Tamin

  • BACE2, a β-secretase homolog, cleaves at the β site and within the amyloid-β region of the amyloid-β precursor protein

    Michael Farzan;Christine E. Schnitzler;Natalya Vasilieva;Doris Leung

  • IFITM-Family Proteins: The Cell's First Line of Antiviral Defense

    Charles C. Bailey;Guocai Zhong;I-Chueh Huang;Michael Farzan

  • Angiotensin-converting enzyme 2: a functional receptor for SARS coronavirus.

    J. H. Kuhn;W. Li;H. Choe;M. Farzan

Frequent Co-Authors

Hyeryun Choe
Hyeryun Choe Scripps Research Institute
Wenhui Li
Wenhui Li Tsinghua University
Joseph Sodroski
Joseph Sodroski Harvard Medical School
Jens H. Kuhn
Jens H. Kuhn National Institutes of Health
Craig Gerard
Craig Gerard Boston Children's Hospital
Norma P. Gerard
Norma P. Gerard Boston Children's Hospital
Wayne A. Marasco
Wayne A. Marasco Harvard University
Stephen C. Harrison
Stephen C. Harrison Harvard University
Richard T. Wyatt
Richard T. Wyatt Scripps Research Institute
Peter D. Kwong
Peter D. Kwong Columbia University Medical Center

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