D-Index & Metrics Best Publications

D-Index & Metrics

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Immunology D-index 72 Citations 19,630 141 World Ranking 937 National Ranking 511
Medicine D-index 80 Citations 21,886 171 World Ranking 9438 National Ranking 5108

Research.com Recognitions

Awards & Achievements

Member of the Association of American Physicians

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Immune system
  • Virus

James A. Hoxie focuses on Virology, Molecular biology, Antibody, Virus and Chemokine receptor. His studies in Virology integrate themes in fields like CXCR4, Immunology, Immune system and Glycoprotein. His biological study spans a wide range of topics, including Receptor, Biochemistry and Peptide sequence.

His study in Antibody is interdisciplinary in nature, drawing from both Cell culture and Antigen. His study looks at the intersection of Virus and topics like Protein structure with V3 loop. His studies deal with areas such as T cell and Cell biology as well as Chemokine receptor.

His most cited work include:

  • The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes (983 citations)
  • Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation. (841 citations)
  • Detection of activated platelets in whole blood using activation- dependent monoclonal antibodies and flow cytometry (670 citations)

What are the main themes of his work throughout his whole career to date?

His main research concerns Virology, Molecular biology, Virus, Antibody and Immunology. His Virology research incorporates elements of Epitope and Monoclonal antibody. The various areas that James A. Hoxie examines in his Molecular biology study include Cell culture, Chromosomal translocation, Antigen, Receptor and Binding site.

His work carried out in the field of Receptor brings together such families of science as Thrombin and Thrombin receptor. James A. Hoxie combines subjects such as Gp41, Cell fusion and CXCR4 with his study of Virus. James A. Hoxie works mostly in the field of Simian immunodeficiency virus, limiting it down to topics relating to Glycoprotein and, in certain cases, Transmembrane protein.

He most often published in these fields:

  • Virology (56.84%)
  • Molecular biology (30.34%)
  • Virus (28.63%)

What were the highlights of his more recent work (between 2012-2021)?

  • Virology (56.84%)
  • Antibody (23.50%)
  • Simian immunodeficiency virus (12.82%)

In recent papers he was focusing on the following fields of study:

James A. Hoxie mainly investigates Virology, Antibody, Simian immunodeficiency virus, Virus and T cell. The concepts of his Virology study are interwoven with issues in Mutation, Macrophage and Immunology. As part of one scientific family, James A. Hoxie deals mainly with the area of Mutation, narrowing it down to issues related to the Immunodeficiency virus, and often Molecular biology.

The Antibody study combines topics in areas such as Protein structure, Receptor, Acquired immunodeficiency syndrome and In vivo. His Simian immunodeficiency virus research integrates issues from Epitope, Viral replication and Glycoprotein. His Virus study combines topics from a wide range of disciplines, such as Fitness cost, Downregulation and upregulation, Flow cytometry and Signal transducing adaptor protein.

Between 2012 and 2021, his most popular works were:

  • Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption (241 citations)
  • Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor (175 citations)
  • Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy–treated macaques (96 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Immune system
  • Virus

His primary areas of study are Virology, Immunology, Viremia, Virus and Antibody. His research in Virology intersects with topics in Cell culture and Active immunization. His Immunology research is multidisciplinary, incorporating perspectives in Blockade, Hematopoietic stem cell transplantation and Maraviroc.

His Viremia research includes elements of RNA, Chronic infection, DNA and Phylogenetic tree. His research integrates issues of Phenotype, Gene, Macrophage and Cell type in his study of Virus. His Antibody research is multidisciplinary, relying on both Infectious disease, Clinical trial, Tuberculosis and Coinfection.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes

Conrad C. Bleul;Lijun Wu;James A. Hoxie;Timothy A. Springer.
Proceedings of the National Academy of Sciences of the United States of America (1997)

1367 Citations

Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation.

S J Shattil;J A Hoxie;M Cunningham;L F Brass.
Journal of Biological Chemistry (1985)

1333 Citations

Detection of activated platelets in whole blood using activation- dependent monoclonal antibodies and flow cytometry

Sanford J. Shattil;Michael Cunningham;James A. Hoxie.
Blood (1987)

1040 Citations

Interactions of Mast Cell Tryptase with Thrombin Receptors and PAR-2

Marina Molino;Elliot S. Barnathan;Robert Numerof;Jim Clark.
Journal of Biological Chemistry (1997)

885 Citations

CD4-Independent Infection by HIV-2 Is Mediated by Fusin/CXCR4

Michael J Endres;Paul R Clapham;Mark Marsh;Ména Ahuja.
Cell (1996)

810 Citations

Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1α is mediated by the chemokine receptor CXCR4

Joseph Hesselgesser;Dennis Taub;Padmavathi Baskar;Michael Greenberg.
Current Biology (1998)

474 Citations

The chemokine SDF‐1, stromal cell‐derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4

Massimo D'Apuzzo;Antonius Rolink;Marcel Loetscher;James A. Hoxie.
European Journal of Immunology (1997)

473 Citations

Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4

Natalie Signoret;Joanne Oldridge;Annegret Pelchen-Matthews;Per J. Klasse.
Journal of Cell Biology (1997)

453 Citations

Alterations in T4 (CD4) protein and mRNA synthesis in cells infected with HIV.

James A. Hoxie;James D. Alpers;Jerome L. Rackowski;Kay Huebner.
Science (1986)

432 Citations

Stable exposure of the coreceptor-binding site in a CD4-independent HIV-1 envelope protein

Trevor L. Hoffman;Celia C. LaBranche;Wentao Zhang;Gabriella Canziani.
Proceedings of the National Academy of Sciences of the United States of America (1999)

393 Citations

Best Scientists Citing James A. Hoxie

David C. Montefiori

David C. Montefiori

Duke University

Publications: 229

John R. Mascola

John R. Mascola

National Institutes of Health

Publications: 147

Barton F. Haynes

Barton F. Haynes

Duke University

Publications: 133

Joseph Sodroski

Joseph Sodroski

Harvard University

Publications: 125

Dennis R. Burton

Dennis R. Burton

Scripps Research Institute

Publications: 121

John P. Moore

John P. Moore

Cornell University

Publications: 104

Georgia D. Tomaras

Georgia D. Tomaras

Duke University

Publications: 101

Guido Ferrari

Guido Ferrari

Duke University

Publications: 100

Robert W. Doms

Robert W. Doms

Children's Hospital of Philadelphia

Publications: 97

Peter D. Kwong

Peter D. Kwong

National Institutes of Health

Publications: 96

Lynn Morris

Lynn Morris

University of the Witwatersrand

Publications: 85

George M. Shaw

George M. Shaw

University of Pennsylvania

Publications: 85

Andrés Finzi

Andrés Finzi

University of Montreal

Publications: 85

Richard T. Wyatt

Richard T. Wyatt

Scripps Research Institute

Publications: 74

Michael S. Seaman

Michael S. Seaman

Beth Israel Deaconess Medical Center

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Profile was last updated on December 6th, 2021.
Research.com Ranking is based on data retrieved from the Microsoft Academic Graph (MAG).
The ranking d-index is inferred from publications deemed to belong to the considered discipline.

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