What is he best known for?
The fields of study he is best known for:
James A. Hoxie focuses on Virology, Molecular biology, Antibody, Virus and Chemokine receptor.
His studies in Virology integrate themes in fields like CXCR4, Immunology, Immune system and Glycoprotein.
His biological study spans a wide range of topics, including Receptor, Biochemistry and Peptide sequence.
His study in Antibody is interdisciplinary in nature, drawing from both Cell culture and Antigen.
His study looks at the intersection of Virus and topics like Protein structure with V3 loop.
His studies deal with areas such as T cell and Cell biology as well as Chemokine receptor.
His most cited work include:
- The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes (983 citations)
- Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation. (841 citations)
- Detection of activated platelets in whole blood using activation- dependent monoclonal antibodies and flow cytometry (670 citations)
What are the main themes of his work throughout his whole career to date?
His main research concerns Virology, Molecular biology, Virus, Antibody and Immunology.
His Virology research incorporates elements of Epitope and Monoclonal antibody.
The various areas that James A. Hoxie examines in his Molecular biology study include Cell culture, Chromosomal translocation, Antigen, Receptor and Binding site.
His work carried out in the field of Receptor brings together such families of science as Thrombin and Thrombin receptor.
James A. Hoxie combines subjects such as Gp41, Cell fusion and CXCR4 with his study of Virus.
James A. Hoxie works mostly in the field of Simian immunodeficiency virus, limiting it down to topics relating to Glycoprotein and, in certain cases, Transmembrane protein.
He most often published in these fields:
- Virology (56.84%)
- Molecular biology (30.34%)
- Virus (28.63%)
What were the highlights of his more recent work (between 2012-2021)?
- Virology (56.84%)
- Antibody (23.50%)
- Simian immunodeficiency virus (12.82%)
In recent papers he was focusing on the following fields of study:
James A. Hoxie mainly investigates Virology, Antibody, Simian immunodeficiency virus, Virus and T cell.
The concepts of his Virology study are interwoven with issues in Mutation, Macrophage and Immunology.
As part of one scientific family, James A. Hoxie deals mainly with the area of Mutation, narrowing it down to issues related to the Immunodeficiency virus, and often Molecular biology.
The Antibody study combines topics in areas such as Protein structure, Receptor, Acquired immunodeficiency syndrome and In vivo.
His Simian immunodeficiency virus research integrates issues from Epitope, Viral replication and Glycoprotein.
His Virus study combines topics from a wide range of disciplines, such as Fitness cost, Downregulation and upregulation, Flow cytometry and Signal transducing adaptor protein.
Between 2012 and 2021, his most popular works were:
- Effect of HIV Antibody VRC01 on Viral Rebound after Treatment Interruption (241 citations)
- Neutralizing antibodies to HIV-1 envelope protect more effectively in vivo than those to the CD4 receptor (175 citations)
- Whole-body immunoPET reveals active SIV dynamics in viremic and antiretroviral therapy–treated macaques (96 citations)
In his most recent research, the most cited papers focused on:
His primary areas of study are Virology, Immunology, Viremia, Virus and Antibody.
His research in Virology intersects with topics in Cell culture and Active immunization.
His Immunology research is multidisciplinary, incorporating perspectives in Blockade, Hematopoietic stem cell transplantation and Maraviroc.
His Viremia research includes elements of RNA, Chronic infection, DNA and Phylogenetic tree.
His research integrates issues of Phenotype, Gene, Macrophage and Cell type in his study of Virus.
His Antibody research is multidisciplinary, relying on both Infectious disease, Clinical trial, Tuberculosis and Coinfection.
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