Member of the Association of American Physicians
James A. Hoxie focuses on Virology, Molecular biology, Antibody, Virus and Chemokine receptor. His studies in Virology integrate themes in fields like CXCR4, Immunology, Immune system and Glycoprotein. His biological study spans a wide range of topics, including Receptor, Biochemistry and Peptide sequence.
His study in Antibody is interdisciplinary in nature, drawing from both Cell culture and Antigen. His study looks at the intersection of Virus and topics like Protein structure with V3 loop. His studies deal with areas such as T cell and Cell biology as well as Chemokine receptor.
His main research concerns Virology, Molecular biology, Virus, Antibody and Immunology. His Virology research incorporates elements of Epitope and Monoclonal antibody. The various areas that James A. Hoxie examines in his Molecular biology study include Cell culture, Chromosomal translocation, Antigen, Receptor and Binding site.
His work carried out in the field of Receptor brings together such families of science as Thrombin and Thrombin receptor. James A. Hoxie combines subjects such as Gp41, Cell fusion and CXCR4 with his study of Virus. James A. Hoxie works mostly in the field of Simian immunodeficiency virus, limiting it down to topics relating to Glycoprotein and, in certain cases, Transmembrane protein.
James A. Hoxie mainly investigates Virology, Antibody, Simian immunodeficiency virus, Virus and T cell. The concepts of his Virology study are interwoven with issues in Mutation, Macrophage and Immunology. As part of one scientific family, James A. Hoxie deals mainly with the area of Mutation, narrowing it down to issues related to the Immunodeficiency virus, and often Molecular biology.
The Antibody study combines topics in areas such as Protein structure, Receptor, Acquired immunodeficiency syndrome and In vivo. His Simian immunodeficiency virus research integrates issues from Epitope, Viral replication and Glycoprotein. His Virus study combines topics from a wide range of disciplines, such as Fitness cost, Downregulation and upregulation, Flow cytometry and Signal transducing adaptor protein.
His primary areas of study are Virology, Immunology, Viremia, Virus and Antibody. His research in Virology intersects with topics in Cell culture and Active immunization. His Immunology research is multidisciplinary, incorporating perspectives in Blockade, Hematopoietic stem cell transplantation and Maraviroc.
His Viremia research includes elements of RNA, Chronic infection, DNA and Phylogenetic tree. His research integrates issues of Phenotype, Gene, Macrophage and Cell type in his study of Virus. His Antibody research is multidisciplinary, relying on both Infectious disease, Clinical trial, Tuberculosis and Coinfection.
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The HIV coreceptors CXCR4 and CCR5 are differentially expressed and regulated on human T lymphocytes
Conrad C. Bleul;Lijun Wu;James A. Hoxie;Timothy A. Springer.
Proceedings of the National Academy of Sciences of the United States of America (1997)
Changes in the platelet membrane glycoprotein IIb.IIIa complex during platelet activation.
S J Shattil;J A Hoxie;M Cunningham;L F Brass.
Journal of Biological Chemistry (1985)
Detection of activated platelets in whole blood using activation- dependent monoclonal antibodies and flow cytometry
Sanford J. Shattil;Michael Cunningham;James A. Hoxie.
Interactions of Mast Cell Tryptase with Thrombin Receptors and PAR-2
Marina Molino;Elliot S. Barnathan;Robert Numerof;Jim Clark.
Journal of Biological Chemistry (1997)
CD4-Independent Infection by HIV-2 Is Mediated by Fusin/CXCR4
Michael J Endres;Paul R Clapham;Mark Marsh;Ména Ahuja.
Neuronal apoptosis induced by HIV-1 gp120 and the chemokine SDF-1α is mediated by the chemokine receptor CXCR4
Joseph Hesselgesser;Dennis Taub;Padmavathi Baskar;Michael Greenberg.
Current Biology (1998)
Alterations in T4 (CD4) protein and mRNA synthesis in cells infected with HIV.
James A. Hoxie;James D. Alpers;Jerome L. Rackowski;Kay Huebner.
The chemokine SDF‐1, stromal cell‐derived factor 1, attracts early stage B cell precursors via the chemokine receptor CXCR4
Massimo D'Apuzzo;Antonius Rolink;Marcel Loetscher;James A. Hoxie.
European Journal of Immunology (1997)
Phorbol Esters and SDF-1 Induce Rapid Endocytosis and Down Modulation of the Chemokine Receptor CXCR4
Natalie Signoret;Joanne Oldridge;Annegret Pelchen-Matthews;Per J. Klasse.
Journal of Cell Biology (1997)
Inhibition of fibrinogen binding to stimulated human platelets by a monoclonal antibody.
Joel S. Bennett;James A. Hoxie;Susan F. Leitman;Gaston Vilaire.
Proceedings of the National Academy of Sciences of the United States of America (1983)
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