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Neuroscience

D-Index
68
Citations
15737
World Ranking
2761
National Ranking
69

Overview

What is he best known for?

The fields of study he is best known for:

  • Internal medicine
  • Enzyme
  • Gene

Kim Q. Do focuses on Neuroscience, Oxidative stress, Schizophrenia, Glutathione and Internal medicine. As a part of the same scientific family, he mostly works in the field of Neuroscience, focusing on Reactive oxygen species and, on occasion, Extracellular, Oxidative phosphorylation, Inhibitory postsynaptic potential, Intracellular and Superoxide dismutase. The study incorporates disciplines such as Psychosis, Prefrontal cortex, GABAergic and Disease in addition to Schizophrenia.

His study with Glutathione involves better knowledge in Biochemistry. The Internal medicine study combines topics in areas such as Acetylcysteine and Endocrinology. His Endocrinology research integrates issues from NMDA receptor, Long-term potentiation and Synaptic plasticity.

His most cited work include:

  • Schizophrenia: glutathione deficit in cerebrospinal fluid and prefrontal cortex in vivo. (419 citations)
  • N-acetyl cysteine as a glutathione precursor for schizophrenia--a double-blind, randomized, placebo-controlled trial. (399 citations)
  • Murine brain macrophages induce NMDA receptor mediated neurotoxicity in vitro by secreting glutamate (387 citations)

What are the main themes of his work throughout his whole career to date?

His primary areas of study are Neuroscience, Schizophrenia, Glutathione, Oxidative stress and Internal medicine. In his research on the topic of Neuroscience, Homocysteic acid is strongly related with NMDA receptor. His research in Schizophrenia intersects with topics in Acetylcysteine, White matter, Psychosis and Pathophysiology.

His study in the field of GCLC is also linked to topics like Ascorbic acid. His research integrates issues of Hippocampal formation, Neuroinflammation, Disease, Redox and Web of science in his study of Oxidative stress. His study focuses on the intersection of Internal medicine and fields such as Endocrinology with connections in the field of GCLM.

He most often published in these fields:

  • Neuroscience (35.44%)
  • Schizophrenia (25.74%)
  • Glutathione (23.21%)

What were the highlights of his more recent work (between 2016-2021)?

  • Neuroscience (35.44%)
  • Schizophrenia (25.74%)
  • Psychosis (14.77%)

In recent papers he was focusing on the following fields of study:

His primary scientific interests are in Neuroscience, Schizophrenia, Psychosis, Oxidative stress and Internal medicine. His research in Neuroscience focuses on subjects like Schizophrenia, which are connected to Face, Cognitive psychology and Brain development. His Schizophrenia research is multidisciplinary, incorporating elements of Acetylcysteine and Pathophysiology.

The concepts of his Oxidative stress study are interwoven with issues in NMDA receptor, Neuroinflammation, Glutathione and Cell biology. His Glutathione study integrates concerns from other disciplines, such as Biomarker and Pharmacology. His Internal medicine research includes elements of White matter, Fractional anisotropy, Endocrinology and Oncology.

Between 2016 and 2021, his most popular works were:

  • Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia. (133 citations)
  • Nrf2-dependent persistent oxidative stress results in stress-induced vulnerability to depression (68 citations)
  • N-acetylcysteine in a Double-Blind Randomized Placebo-Controlled Trial: Toward Biomarker-Guided Treatment in Early Psychosis. (64 citations)

In his most recent research, the most cited papers focused on:

  • Internal medicine
  • Enzyme
  • Gene

His scientific interests lie mostly in Oxidative stress, Schizophrenia, Neuroscience, Psychosis and Internal medicine. His research integrates issues of Neuroinflammation, Glutathione, Endogeny and Cell biology in his study of Oxidative stress. His Schizophrenia research is multidisciplinary, relying on both Acetylcysteine and Evoked potential.

His biological study spans a wide range of topics, including Glutamate receptor, NMDA receptor and Microglia. Kim Q. Do has researched Psychosis in several fields, including Mismatch negativity, Sensory system, Audiology and Contingent negative variation. His studies deal with areas such as Fractional anisotropy, Endocrinology and Psychopharmacology as well as Internal medicine.

Best Publications

  • N-acetyl cysteine as a glutathione precursor for schizophrenia--a double-blind, randomized, placebo-controlled trial.

    Michael Berk;David Leon Copolov;David Leon Copolov;Olivia Dean;Olivia Dean;Kristy Lu

  • Schizophrenia: glutathione deficit in cerebrospinal fluid and prefrontal cortex in vivo.

    K. Q. Do;A. H. Trabesinger;M. Kirsten-Krüger;C. J. Lauer

  • Perineuronal nets protect fast-spiking interneurons against oxidative stress

    Jan-Harry Cabungcal;Pascal Steullet;Hirofumi Morishita;Rudolf Kraftsik

  • Murine brain macrophages induce NMDA receptor mediated neurotoxicity in vitro by secreting glutamate

    Daniela Piani;Karl Frei;Kim Quang Do;Michel Cuénod

  • Mapping the human connectome at multiple scales with diffusion spectrum MRI.

    Leila Cammoun;Xavier Gigandet;Djalel Eddine Meskaldji;Jean-Philippe Thiran

  • Redox dysregulation, neurodevelopment, and schizophrenia

    Kim Q Do;Jan H Cabungcal;Anita Frank;Pascal Steullet

  • Glutathione precursor, N-acetyl-cysteine, improves mismatch negativity in schizophrenia patients.

    Suzie Lavoie;Micah M Murray;Patricia Deppen;Maria G Knyazeva

  • Prevention of Psychosis: Advances in Detection, Prognosis, and Intervention

    Paolo Fusar-Poli;Gonzalo Salazar de Pablo;Gonzalo Salazar de Pablo;Christoph U. Correll;Andreas Meyer-Lindenberg

  • Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia.

    P Steullet;J H Cabungcal;J Coyle;M Didriksen

  • Impaired glutathione synthesis in schizophrenia: Convergent genetic and functional evidence

    René Gysin;Rudolf Kraftsik;Julie Sandell;Pierre Bovet

  • Linking early-life NMDAR hypofunction and oxidative stress in schizophrenia pathogenesis

    Giles E. Hardingham;Kim Q. Do

  • Early-life insults impair parvalbumin interneurons via oxidative stress: reversal by N-acetylcysteine.

    Jan-Harry Cabungcal;Pascal Steullet;Rudolf Kraftsik;Michel Cuenod

  • Redox Dysregulation Affects the Ventral But Not Dorsal Hippocampus: Impairment of Parvalbumin Neurons, Gamma Oscillations, and Related Behaviors

    Pascal Steullet;Jan-Harry Cabungcal;Anita Kulak;Rudolf Kraftsik

  • Schizophrenia and Oxidative Stress: Glutamate Cysteine Ligase Modifier as a Susceptibility Gene

    Mirjana Tosic;Jurg Ott;Sandra Barral;Pierre Bovet

  • Redox dysregulation, neuroinflammation, and NMDA receptor hypofunction: A “central hub” in schizophrenia pathophysiology?

    P. Steullet;J.H. Cabungcal;A. Monin;D. Dwir

  • Nrf2-dependent persistent oxidative stress results in stress-induced vulnerability to depression

    Bouvier E;Bouvier E;Bouvier E;Brouillard F;Brouillard F;Molet J;Molet J;Molet J;Claverie D

  • S-nitrosoglutathione in rat cerebellum: identification and quantification by liquid chromatography-mass spectrometry.

    Ina Kluge;Ursula Gutteck-Amsler;Markus Zollinger;Kim Quang Do

  • Synaptic plasticity impairment and hypofunction of NMDA receptors induced by glutathione deficit: relevance to schizophrenia.

    P. Steullet;H.C. Neijt;M. Cuénod;K.Q. Do

  • TORC1 is a calcium- and cAMP-sensitive coincidence detector involved in hippocampal long-term synaptic plasticity

    Krisztián A. Kovács;Pascal Steullet;Myriam Steinmann;Kim Q. Do

  • In vitro release of endogenous excitatory sulfur-containing amino acids from various rat brain regions

    Kim Quang Do;Marianne Mattenberger;Peter Streit;Michel Cuénod

  • Tau accumulation in astrocytes of the dentate gyrus induces neuronal dysfunction and memory deficits in Alzheimer's disease.

    Kevin Richetin;Pascal Steullet;Mathieu Pachoud;Romain Perbet

Frequent Co-Authors

Michel Cuenod
Michel Cuenod University of Lausanne
Patric Hagmann
Patric Hagmann University of Lausanne
Peter Streit
Peter Streit University of Zurich
Maria G. Knyazeva
Maria G. Knyazeva University of Lausanne
Olaf Blanke
Olaf Blanke École Polytechnique Fédérale de Lausanne
Pierre J. Magistretti
Pierre J. Magistretti École Polytechnique Fédérale de Lausanne
Patricio O'Donnell
Patricio O'Donnell Alto Neuroscience
Thomas E. Salt
Thomas E. Salt University College London
Takao K. Hensch
Takao K. Hensch Harvard University
Philip McGuire
Philip McGuire University of Oxford

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