World's Best Scientists 2026 revealed!
Patricio O'Donnell

Patricio O'Donnell

D-Index & Metrics

Neuroscience

D-Index
64
Citations
15684
World Ranking
3248
National Ranking
1507

Overview

Patricio O'Donnell is affiliated with Alto Neuroscience in the United States. Their research contributions predominantly fall within the fields of Neuroscience and Medicine, with specific expertise in Cognitive Neuroscience, Cellular and Molecular Neuroscience, Molecular Biology, Pharmacology, and Physiology.

Their work covers a range of topics related to brain function and neuropharmacology. These include:

  • Functional Brain Connectivity Studies
  • Treatment of Major Depression
  • Tryptophan and brain disorders
  • Neuroscience and Neuropharmacology Research
  • Neurotransmitter Receptor Influence on Behavior
  • Neural dynamics and brain function
  • Neural and Behavioral Psychology Studies

Recent publications by Patricio O'Donnell highlight ongoing research in neuropsychiatric conditions and brain signal analysis. Notable papers include:

  • Using a smartwatch and smartphone to assess early Parkinson's disease in the WATCH-PD study (2023) - published in npj Parkinson s Disease
  • The D-amino acid oxidase inhibitor luvadaxistat improves mismatch negativity in patients with schizophrenia in a randomized trial (2023) - published in Neuropsychopharmacology
  • GluN2D-mediated excitatory drive onto medial prefrontal cortical PV+ fast-spiking inhibitory interneurons (2020) - published in PLoS ONE
  • Schizophrenia-associated SLC39A8 polymorphism is a loss-of-function allele altering glutamate receptor and innate immune signaling (2021) - published in Translational Psychiatry
  • Validation of a suite of ERP and QEEG biomarkers in a pre-competitive, industry-led study in subjects with schizophrenia and healthy volunteers (2023) - published in Schizophrenia Research

Patricio O'Donnell has frequently collaborated with several researchers within their field. Key coauthors include:

  • Derek L. Buhl
  • Neta Zach
  • Ann Summerfelt
  • Jamie Adams
  • Dmitri Volfson

Their publications are regularly featured in certain specialized venues, reflecting research interests in mental health and neuroscience:

  • Translational Psychiatry
  • UNC Libraries
  • SSRN Electronic Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Research Square (Research Square)

Best Publications

  • Synaptic interactions among excitatory afferents to nucleus accumbens neurons: hippocampal gating of prefrontal cortical input

    P O'Donnell;AA Grace

  • Widespread white matter microstructural differences in schizophrenia across 4322 individuals : results from the ENIGMA Schizophrenia DTI Working Group

    S. Kelly;S. Kelly;N. Jahanshad;A. Zalesky;P. Kochunov

  • Dopamine–Glutamate Interactions Controlling Prefrontal Cortical Pyramidal Cell Excitability Involve Multiple Signaling Mechanisms

    Kuei Y. Tseng;Patricio O'Donnell

  • Dopamine Modulation of Prefrontal Cortical Interneurons Changes during Adolescence

    Kuei-Yuan Tseng;Patricio O'Donnell;Patricio O'Donnell

  • Nucleus Accumbens Medium Spiny Neuron Subtypes Mediate Depression-Related Outcomes to Social Defeat Stress

    T. Chase Francis;Ramesh Chandra;Danielle M. Friend;Eric Finkel

  • Oxidative stress-driven parvalbumin interneuron impairment as a common mechanism in models of schizophrenia.

    P Steullet;J H Cabungcal;J Coyle;M Didriksen

  • Ventral Tegmental Area Afferents to the Prefrontal Cortex Maintain Membrane Potential ‘Up’ States in Pyramidal Neurons via D1 Dopamine Receptors

    Barbara L. Lewis;Patricio O'Donnell

  • Loss of erbB signaling in oligodendrocytes alters myelin and dopaminergic function, a potential mechanism for neuropsychiatric disorders

    Kristine Roy;Joshua C. Murtie;Bassem F. El-Khodor;Nicole Edgar

  • Knockdown of DISC1 by In Utero Gene Transfer Disturbs Postnatal Dopaminergic Maturation in the Frontal Cortex and Leads to Adult Behavioral Deficits

    Minae Niwa;Atsushi Kamiya;Rina Murai;Rina Murai;Ken ichiro Kubo

  • Dopamine gating of forebrain neural ensembles.

    Patricio O'Donnell

  • Expectancy-related changes in firing of dopamine neurons depend on orbitofrontal cortex

    Yuji K Takahashi;Matthew R Roesch;Robert C Wilson;Kathy Toreson

  • D1 Dopamine Receptors Potentiate NMDA-mediated Excitability Increase in Layer V Prefrontal Cortical Pyramidal Neurons

    Jian Wang;Patricio O'Donnell

  • Modulation of cell firing in the nucleus accumbens.

    Patricio O'donnell;Jennifer Greene;Nina Pabello;Barbara L. Lewis

  • Gamma and Delta Neural Oscillations and Association with Clinical Symptoms under Subanesthetic Ketamine

    L Elliot Hong;Ann Summerfelt;Robert W Buchanan;Patricio O'Donnell

  • Redox dysregulation, neuroinflammation, and NMDA receptor hypofunction: A “central hub” in schizophrenia pathophysiology?

    P. Steullet;J.H. Cabungcal;A. Monin;D. Dwir

  • Dysfunctions in Multiple Interrelated Systems as the Neurobiological Bases of Schizophrenic Symptom Clusters

    Patricio O'Donnell;Anthony A. Grace

  • Early Social Experience Is Critical for the Development of Cognitive Control and Dopamine Modulation of Prefrontal Cortex Function

    Petra J J Baarendse;Danielle S Counotte;Patricio O'Donnell;Louk J M J Vanderschuren

  • Dopamine Terminals in the Rat Prefrontal Cortex Synapse on Pyramidal Cells that Project to the Nucleus Accumbens

    David B. Carr;Patricio O'Donnell;J. Patrick Card;Susan R. Sesack

  • NMDA/AMPA ratio impacts state transitions and entrainment to oscillations in a computational model of the nucleus accumbens medium spiny projection neuron

    John A Wolf;Jason T Moyer;Maciej T Lazarewicz;Diego Contreras

  • Tonic D2-mediated attenuation of cortical excitation in nucleus accumbens neurons recorded in vitro.

    Patricio O'Donnell;Anthony A. Grace

  • Turning off cortical ensembles stops striatal Up states and elicits phase perturbations in cortical and striatal slow oscillations in rat in vivo

    Fernando Kasanetz;Luis A. Riquelme;Patricio O'Donnell;M. Gustavo Murer

  • Neurobiology of Mental Illness.

    Patricio O'Donnell

Frequent Co-Authors

Anthony A. Grace
Anthony A. Grace University of Pittsburgh
L. Elliot Hong
L. Elliot Hong University of Maryland, Baltimore
Kuei Y. Tseng
Kuei Y. Tseng University of Illinois at Chicago
Akira Sawa
Akira Sawa Johns Hopkins University
David A. Collier
David A. Collier Eli Lilly (United States)
Kim Q. Do
Kim Q. Do University of Lausanne
Geoffrey Schoenbaum
Geoffrey Schoenbaum National Institutes of Health
Paul M. Thompson
Paul M. Thompson University of Southern California
Laura M. Rowland
Laura M. Rowland University of Maryland, Baltimore
Patrick F. Sullivan
Patrick F. Sullivan University of North Carolina at Chapel Hill

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Patricio O'Donnell

Trending Scientists