World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
127
Citations
77357
World Ranking
288
National Ranking
150

Molecular Biology

D-Index
127
Citations
77357
World Ranking
202
National Ranking
123

Research.com Recognitions

  • 2013 - Member of the National Academy of Sciences
  • 2012 - Fellow of the American Academy of Arts and Sciences
  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Jef D. Boeke is affiliated with New York University in the United States and has an extensive publication record primarily in biochemistry, genetics, and molecular biology. Their research contributions span molecular biology, plant science, genetics, surgery, and cell biology, reflecting a broad interdisciplinary range within the biological sciences.

The scientist's work emphasizes key topics such as CRISPR and genetic engineering, chromosomal and genetic variations, genomics and chromatin dynamics, RNA and protein synthesis mechanisms, fungal and yeast genetics research, RNA research and splicing, and plant virus research studies.

Frequent co-authors in Jef D. Boeke's research include Weimin Zhang, Leslie A. Mitchell, Joel S. Bader, Ran Brosh, and Yizhi Cai, with collaboration counts ranging from over twenty to nearly thirty joint publications each.

Jef D. Boeke has frequently published in several scientific venues. Among the most common are:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cell Genomics
  • Nature Communications
  • Nature
  • Proceedings of the National Academy of Sciences

The researcher's recent notable papers include the following:

  • The role of retrotransposable elements in ageing and age-associated diseases (2021, Nature)
  • Results of Two Cases of Pig-to-Human Kidney Xenotransplantation (2022, New England Journal of Medicine)
  • Widespread Transcriptional Scanning in the Testis Modulates Gene Evolution Rates (2020, Cell)
  • Super-enhancers include classical enhancers and facilitators to fully activate gene expression (2023, Cell)
  • Pig-to-human heart xenotransplantation in two recently deceased human recipients (2023, Nature Medicine)

Throughout their career, Jef D. Boeke has been recognized with several awards, including election to prestigious academies: Member of the National Academy of Sciences in 2013, Fellow of the American Academy of Arts and Sciences in 2012, and Fellow of the American Association for the Advancement of Science (AAAS) in 2007.

Best Publications

  • Designer deletion strains derived from Saccharomyces cerevisiae S288C: a useful set of strains and plasmids for PCR-mediated gene disruption and other applications.

    Carrie Baker Brachmann;Adrian Davies;Gregory J. Cost;Emerita Caputo

  • Functional profiling of the Saccharomyces cerevisiae genome.

    Guri Giaever;Angela M. Chu;Li Ni;Carla Connelly

  • Functional Characterization of the S. cerevisiae Genome by Gene Deletion and Parallel Analysis

    Elizabeth A. Winzeler;Daniel D. Shoemaker;Anna Astromoff;Hong Liang

  • A positive selection for mutants lacking orotidine-5'-phosphate decarboxylase activity in yeast: 5-fluoro-orotic acid resistance.

    Jef D. Boeke;Francois La Croute;Gerald R. Fink

  • 5-Fluoroorotic acid as a selective agent in yeast molecular genetics.

    Jef D. Boeke;Joshua Trueheart;Georges Natsoulis;Gerald R. Fink

  • Human L1 Retrotransposon Encodes a Conserved Endonuclease Required for Retrotransposition

    Qinghua Feng;John V. Moran;Haig H. Kazazian;Jef D. Boeke

  • High Frequency Retrotransposition in Cultured Mammalian Cells

    John V. Moran;Susan E. Holmes;Thierry P. Naas;Ralph J. DeBerardinis

  • Ty elements transpose through an RNA intermediate

    Jef D. Boeke;David J. Garfinkel;Cora A. Styles;Gerald R. Fink

  • A phylogenetically conserved NAD+-dependent protein deacetylase activity in the Sir2 protein family.

    Jeffrey S. Smith;Carrie Baker Brachmann;Carrie Baker Brachmann;Ivana Celic;Margaret A. Kenna;Margaret A. Kenna

  • The Biochemistry of Sirtuins

    Anthony A. Sauve;Cynthia Wolberger;Vern L. Schramm;Jef D. Boeke

  • L1 drives IFN in senescent cells and promotes age-associated inflammation

    Marco De Cecco;Takahiro Ito;Anna P. Petrashen;Amy E. Elias

  • Human L1 retrotransposition: cis preference versus trans complementation.

    Wei Wei;Nicolas Gilbert;Siew Loon Ooi;Joseph F. Lawler

  • Reverse transcriptase encoded by a human transposable element.

    Stephen L. Mathias;Alan F. Scott;Haig H. Kazazian;Jef D. Boeke

  • The SIR2 gene family, conserved from bacteria to humans, functions in silencing, cell cycle progression, and chromosome stability.

    Carrie Baker Brachmann;Joyce M. Sherman;Scott E. Devine;Elizabeth E. Cameron

  • In vitro mutagenesis and plasmid shuffling: from cloned gene to mutant yeast.

    Robert S. Sikorski;Jef D. Boeke

  • An unusual form of transcriptional silencing in yeast ribosomal DNA.

    Jeffrey S. Smith;Jef D. Boeke

  • Sir2-Dependent Activation of Acetyl-CoA Synthetase by Deacetylation of Active Lysine

    V. J. Starai;I. Celic;R. N. Cole;J. D. Boeke

  • SIRT3, a human SIR2 homologue, is an NAD- dependent deacetylase localized to mitochondria

    Patrick Onyango;Ivana Celic;J. Michael McCaffery;Jef D. Boeke

  • Transposable Elements and Genome Organization: A Comprehensive Survey of Retrotransposons Revealed by the Complete Saccharomyces cerevisiae Genome Sequence

    Jin M. Kim;Swathi Vanguri;Jef D. Boeke;Abram Gabriel

  • Total Synthesis of a Functional Designer Eukaryotic Chromosome

    Narayana Annaluru;Héloïse Muller;Leslie A. Mitchell;Sivaprakash Ramalingam

Frequent Co-Authors

Joel S. Bader
Joel S. Bader Johns Hopkins University
David Fenyö
David Fenyö New York University
Kathleen H. Burns
Kathleen H. Burns Harvard University
Martin S. Taylor
Martin S. Taylor Harvard University
Sarah J. Wheelan
Sarah J. Wheelan Johns Hopkins University School of Medicine
Ying-Jin Yuan
Ying-Jin Yuan Tianjin University
Rafael A. Irizarry
Rafael A. Irizarry Harvard University
David J. Garfinkel
David J. Garfinkel University of Georgia
Heng Zhu
Heng Zhu Johns Hopkins University School of Medicine

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