Loren G. Fong

Overview

Best Publications

• Oxidatively modified low density lipoproteins: a potential role in recruitment and retention of monocyte/macrophages during atherogenesis

  Mark T. Quinn;Sampath Parthasarathy;Loren G. Fong;Daniel Steinberg

  1517
  Citations

• High-density lipoprotein inhibits the oxidative modification of low-density lipoprotein.

  Sampath Parthasarathy;Joellen Barnett;Loren G. Fong

  937
  Citations

• Lamins A and C but not lamin B1 regulate nuclear mechanics

  Jan Lammerding;Loren G. Fong;Julie Y. Ji;Karen Reue;Karen Reue

  747
  Citations

• Glycosylphosphatidylinositol-Anchored High-Density Lipoprotein-Binding Protein 1 Plays a Critical Role in the Lipolytic Processing of Chylomicrons

  Anne P. Beigneux;Brandon S.J. Davies;Peter Gin;Michael M. Weinstein

  517
  Citations

• A Protein Farnesyltransferase Inhibitor Ameliorates Disease in a Mouse Model of Progeria

  Loren G. Fong;David Frost;Margarita Meta;Xin Qiao

  380
  Citations

• GPIHBP1 Is Responsible for the Entry of Lipoprotein Lipase into Capillaries

  Brandon S.J. Davies;Anne P. Beigneux;Richard H. Barnes;Yiping Tu

  376
  Citations

• Blocking protein farnesyltransferase improves nuclear blebbing in mouse fibroblasts with a targeted Hutchinson–Gilford progeria syndrome mutation

  Shao H. Yang;Martin O. Bergo;Julia I. Toth;Xin Qiao

  364
  Citations

• Nonenzymatic oxidative cleavage of peptide bonds in apoprotein B-100.

  L G Fong;S Parthasarathy;J L Witztum;D Steinberg

  355
  Citations

• Blocking protein farnesyltransferase improves nuclear shape in fibroblasts from humans with progeroid syndromes

  Julia I. Toth;Shao H. Yang;Xin Qiao;Anne P. Beigneux

  341
  Citations

• A farnesyltransferase inhibitor improves disease phenotypes in mice with a Hutchinson-Gilford progeria syndrome mutation

  Shao H. Yang;Margarita Meta;Xin Qiao;David Frost

  331
  Citations

• Laminopathies and the long strange trip from basic cell biology to therapy

  Howard J. Worman;Loren G. Fong;Antoine Muchir;Stephen G. Young

  308
  Citations

• Thematic Review Series: Lipid Posttranslational Modifications. Prelamin A, Zmpste24, misshapen cell nuclei, and progeria—new evidence suggesting that protein farnesylation could be important for disease pathogenesis

  Stephen G. Young;Loren G. Fong;Susan Michaelis

  305
  Citations

• Prelamin A and lamin A appear to be dispensable in the nuclear lamina

  Loren G. Fong;Jennifer K. Ng;Jan Lammerding;Timothy A. Vickers

  291
  Citations

• Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons.

  Catherine Coffinier;Hea-Jin Jung;Chika Nobumori;Sandy Chang

  268
  Citations

• Heterozygosity for Lmna deficiency eliminates the progeria-like phenotypes in Zmpste24-deficient mice

  Loren G. Fong;Jennifer K. Ng;Margarita Meta;Nathan Coté

  247
  Citations

• Regulation of prelamin A but not lamin C by miR-9, a brain-specific microRNA

  Hea-Jin Jung;Catherine Coffinier;Youngshik Choe;Anne P. Beigneux

  239
  Citations

• Recognition of solubilized apoproteins from delipidated, oxidized low density lipoprotein (LDL) by the acetyl-LDL receptor

  Sampath Parthasarathy;Loren G. Fong;Deborah Otero;Daniel Steinberg

  227
  Citations

• Abnormal development of the cerebral cortex and cerebellum in the setting of lamin B2 deficiency

  Catherine Coffinier;Sandy Y. Chang;Chika Nobumori;Yiping Tu

  206
  Citations

• Progerin elicits disease phenotypes of progeria in mice whether or not it is farnesylated

  Shao H. Yang;Douglas A. Andres;H. Peter Spielmann;Stephen G. Young

  204
  Citations

• PCSK9 function and physiology

  Andrew S. Peterson;Loren G. Fong;Stephen G. Young

  203
  Citations