D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 76 Citations 48,752 200 World Ranking 2125 National Ranking 1178

Research.com Recognitions

Awards & Achievements

2015 - Fellow of the American Association for the Advancement of Science (AAAS)

2012 - Member of the National Academy of Engineering For elucidation of the effects of mechanical forces on cell physiology and stem cell development.

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • DNA

Dennis E. Discher mainly focuses on Biophysics, Cell biology, Polymersome, Polymer chemistry and Cellular differentiation. His Biophysics study integrates concerns from other disciplines, such as Nanotechnology, Spectrin and Biochemistry, Protein folding, Actin. His Cell biology research includes elements of Immunology and Cytoskeleton.

The various areas that he examines in his Polymersome study include Vesicle, Membrane, Liposome and Controlled release. Dennis E. Discher has included themes like Copolymer, Polymer, Chemical engineering and Micelle in his Polymer chemistry study. His Cellular differentiation research incorporates themes from Embryonic stem cell, Lamin, Anatomy, Chromatin and Stem cell.

His most cited work include:

  • Matrix elasticity directs stem cell lineage specification. (9548 citations)
  • Tissue cells feel and respond to the stiffness of their substrate. (4596 citations)
  • Polymer vesicles : Materials science: Soft surfaces (2237 citations)

What are the main themes of his work throughout his whole career to date?

Dennis E. Discher mainly investigates Cell biology, Biophysics, Nanotechnology, Stem cell and Membrane. He has researched Cell biology in several fields, including Cell and Cellular differentiation. The concepts of his Cellular differentiation study are interwoven with issues in Embryonic stem cell, Extracellular matrix and Cell adhesion.

His research integrates issues of Elasticity, Cytoskeleton, Spectrin, Biochemistry and Nucleus in his study of Biophysics. A large part of his Stem cell studies is devoted to Haematopoiesis. He has included themes like Polymersome, Amphiphile and Copolymer in his Vesicle study.

He most often published in these fields:

  • Cell biology (33.73%)
  • Biophysics (29.56%)
  • Nanotechnology (12.90%)

What were the highlights of his more recent work (between 2016-2021)?

  • Cell biology (33.73%)
  • DNA damage (5.56%)
  • Biophysics (29.56%)

In recent papers he was focusing on the following fields of study:

Cell biology, DNA damage, Biophysics, DNA repair and Nucleus are his primary areas of study. Dennis E. Discher studies Cell biology, focusing on Extracellular matrix in particular. His study in Extracellular matrix is interdisciplinary in nature, drawing from both Cellular differentiation and Cytoskeleton.

His Biophysics study integrates concerns from other disciplines, such as Lamin, Membrane and Collagenase. His Lamin study incorporates themes from Nuclear protein, Matrix, Mesenchymal stem cell and Myosin. His DNA repair study combines topics from a wide range of disciplines, such as Molecular biology, Chromosome and Induced pluripotent stem cell.

Between 2016 and 2021, his most popular works were:

  • Mitotic progression following DNA damage enables pattern recognition within micronuclei (509 citations)
  • Mesenchymal stem cell perspective: cell biology to clinical progress (229 citations)
  • Mechanosensing by the nucleus: From pathways to scaling relationships. (179 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • DNA

His primary areas of study are Cell biology, Nucleus, DNA damage, Lamin and Biophysics. His Cell biology research is multidisciplinary, incorporating perspectives in Nuclear lamina and Cytoskeleton. The concepts of his DNA damage study are interwoven with issues in Cell cycle and DNA repair.

His Biophysics study also includes

  • Chromatin together with Interstitial space, Viscoelasticity, Lipid bilayer, Programmed cell death and Anatomy,
  • Receptor which is related to area like Cooperativity, Traction force microscopy, Lamin B receptor, Adipogenesis and Vesicle. His Extracellular matrix research includes themes of Cellular differentiation, Progenitor cell, Stem cell, Durotaxis and Skeletal muscle. His work carried out in the field of Cellular differentiation brings together such families of science as Mesenchymal stem cell, Progerin, Mutant and Retinoic acid.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Matrix elasticity directs stem cell lineage specification.

Adam J. Engler;Shamik Sen;H. Lee Sweeney;Dennis E. Discher.
Cell (2006)

12553 Citations

Tissue cells feel and respond to the stiffness of their substrate.

Dennis E. Discher;Paul Janmey;Yu Li Wang.
Science (2005)

6123 Citations

Polymer vesicles : Materials science: Soft surfaces

Dennis E. Discher;Adi Eisenberg.
Science (2002)

3514 Citations

Polymersomes: tough vesicles made from diblock copolymers.

Bohdana M. Discher;You Yeon Won;David S. Ege;James C M Lee.
Science (1999)

2570 Citations

Shape effects of filaments versus spherical particles in flow and drug delivery.

Yan Geng;Paul Dalhaimer;Shenshen Cai;Richard Tsai.
Nature Nanotechnology (2007)

2380 Citations

Growth Factors, Matrices, and Forces Combine and Control Stem Cells

Dennis E. Discher;David J. Mooney;Peter W. Zandstra.
Science (2009)

2378 Citations

Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments

Adam J. Engler;Maureen A. Griffin;Shamik Sen;Carsten G. Bönnemann.
Journal of Cell Biology (2004)

1757 Citations

Nuclear lamin-A Scales With Tissue Stiffness and Enhances Matrix-Directed Differentiation

Joe Swift;Irena L. Ivanovska;Amnon Buxboim;Takamasa Harada.
Science (2013)

1332 Citations

Substrate Compliance versus Ligand Density in Cell on Gel Responses

Adam Engler;Lucie Bacakova;Cynthia Newman;Alina Hategan.
Biophysical Journal (2004)

1258 Citations

Bio-inspired, bioengineered and biomimetic drug delivery carriers

Jin-Wook Yoo;Jin-Wook Yoo;Darrell J. Irvine;Darrell J. Irvine;Darrell J. Irvine;Dennis E. Discher;Samir Mitragotri.
Nature Reviews Drug Discovery (2011)

865 Citations

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