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D-Index & Metrics

Biology and Biochemistry

D-Index
110
Citations
86715
World Ranking
955
National Ranking
593

Dennis E. Discher publication distribution in Biology and Biochemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Biology and Biochemistry in 2026. The highlighted bar marks where Dennis E. Discher sits on this spectrum.

47–56 publications: 8 scientists 57–66 publications: 35 scientists 67–76 publications: 106 scientists 77–86 publications: 231 scientists 87–96 publications: 414 scientists 97–106 publications: 546 scientists 107–116 publications: 704 scientists 117–126 publications: 849 scientists 127–136 publications: 980 scientists 137–146 publications: 942 scientists 147–156 publications: 969 scientists 157–166 publications: 950 scientists 167–176 publications: 951 scientists 177–186 publications: 915 scientists 187–196 publications: 787 scientists 197–206 publications: 841 scientists 207–216 publications: 735 scientists 217–226 publications: 709 scientists 227–236 publications: 651 scientists 237–246 publications: 605 scientists 247–256 publications: 510 scientists 257–266 publications: 524 scientists 267–276 publications: 434 scientists 277–286 publications: 418 scientists 287–296 publications: 350 scientists 297–306 publications: 363 scientists 307–316 publications: 315 scientists 317–326 publications: 296 scientists 327–336 publications: 261 scientists 337–346 publications: 240 scientists 347–356 publications: 219 scientists 357–366 publications: 197 scientists 367–376 publications: 154 scientists 377–386 publications: 161 scientists 387–396 publications: 155 scientists 397–406 publications: 145 scientists 407–416 publications: 124 scientists 417–426 publications: 112 scientists 427–436 publications: 132 scientists 437–446 publications: 116 scientists 447–456 publications: 99 scientists 457–466 publications: 81 scientists 467–476 publications: 91 scientists 477–486 publications: 80 scientists 487–496 publications: 80 scientists 497–506 publications: 60 scientists 507–516 publications: 36 scientists 517–526 publications: 46 scientists 527–536 publications: 54 scientists 537–546 publications: 44 scientists 547–556 publications: 43 scientists 557–566 publications: 43 scientists 567–576 publications: 42 scientists 577–586 publications: 25 scientists 587–596 publications: 34 scientists 597–606 publications: 23 scientists 607–616 publications: 33 scientists 617–626 publications: 31 scientists 627–636 publications: 27 scientists 637–646 publications: 25 scientists 647–656 publications: 28 scientists 657–666 publications: 34 scientists 667–676 publications: 18 scientists 677–686 publications: 16 scientists 687–696 publications: 10 scientists 697–706 publications: 12 scientists 707–716 publications: 21 scientists 717–726 publications: 12 scientists 727–736 publications: 12 scientists 737–746 publications: 10 scientists 747–756 publications: 7 scientists 757–766 publications: 13 scientists 767–776 publications: 15 scientists 777–786 publications: 13 scientists 787–796 publications: 9 scientists 797–806 publications: 9 scientists 807–816 publications: 7 scientists 817–826 publications: 4 scientists 827–836 publications: 9 scientists 837–846 publications: 7 scientists 847–856 publications: 3 scientists 857–866 publications: 5 scientists 867–876 publications: 5 scientists 877–886 publications: 11 scientists 887–896 publications: 3 scientists 897–906 publications: 4 scientists 907–916 publications: 7 scientists 917–926 publications: 5 scientists 927–936 publications: 6 scientists 937–946 publications: 6 scientists 947–956 publications: 3 scientists 957–966 publications: 7 scientists 967–976 publications: 2 scientists 977–986 publications: 2 scientists 987–996 publications: 1 scientists 997–1,006 publications: 5 scientists 1,007–1,016 publications: 2 scientists 1,017–1,026 publications: 2 scientists 1,027 publications: 1 scientists 1,028+ publications: 100 scientists
47 publications 1,028+

This scientist: 502 publications — 95th percentile

95% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,028 publications or more.

Dennis E. Discher D-index placement in Biology and Biochemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Biology and Biochemistry scientists ranked by Research.com in 2026. The highlighted bar marks where Dennis E. Discher sits on this spectrum.

40–41 D-Index: 80 scientists 42–43 D-Index: 183 scientists 44–45 D-Index: 317 scientists 46–47 D-Index: 504 scientists 48–49 D-Index: 718 scientists 50–51 D-Index: 900 scientists 52–53 D-Index: 1,026 scientists 54–55 D-Index: 1,150 scientists 56–57 D-Index: 1,236 scientists 58–59 D-Index: 1,253 scientists 60–61 D-Index: 1,163 scientists 62–63 D-Index: 1,131 scientists 64–65 D-Index: 1,032 scientists 66–67 D-Index: 897 scientists 68–69 D-Index: 814 scientists 70–71 D-Index: 715 scientists 72–73 D-Index: 709 scientists 74–75 D-Index: 596 scientists 76–77 D-Index: 512 scientists 78–79 D-Index: 473 scientists 80–81 D-Index: 412 scientists 82–83 D-Index: 373 scientists 84–85 D-Index: 358 scientists 86–87 D-Index: 285 scientists 88–89 D-Index: 273 scientists 90–91 D-Index: 227 scientists 92–93 D-Index: 208 scientists 94–95 D-Index: 193 scientists 96–97 D-Index: 153 scientists 98–99 D-Index: 157 scientists 100–101 D-Index: 148 scientists 102–103 D-Index: 120 scientists 104–105 D-Index: 113 scientists 106–107 D-Index: 100 scientists 108–109 D-Index: 86 scientists 110–111 D-Index: 67 scientists 112–113 D-Index: 72 scientists 114–115 D-Index: 73 scientists 116–117 D-Index: 64 scientists 118–119 D-Index: 53 scientists 120–121 D-Index: 60 scientists 122–123 D-Index: 54 scientists 124–125 D-Index: 43 scientists 126–127 D-Index: 38 scientists 128–129 D-Index: 49 scientists 130–131 D-Index: 26 scientists 132–133 D-Index: 18 scientists 134–135 D-Index: 23 scientists 136–137 D-Index: 32 scientists 138–139 D-Index: 32 scientists 140–141 D-Index: 27 scientists 142–143 D-Index: 19 scientists 144–145 D-Index: 22 scientists 146–147 D-Index: 12 scientists 148–149 D-Index: 16 scientists 150–151 D-Index: 14 scientists 152–153 D-Index: 10 scientists 154–155 D-Index: 13 scientists 156–157 D-Index: 10 scientists 158–159 D-Index: 7 scientists 160–161 D-Index: 9 scientists 162–163 D-Index: 13 scientists 164–165 D-Index: 4 scientists 166 D-Index: 4 scientists 167+ D-Index: 98 scientists
40 D-Index 167+

This scientist: 110 D-Index — 95th percentile

95% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 167 D-Index or more.

Research.com Recognitions

  • 2015 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2012 - Member of the National Academy of Engineering For elucidation of the effects of mechanical forces on cell physiology and stem cell development.

Overview

Dennis E. Discher is affiliated with the University of Pennsylvania in the United States. Their research spans multiple fields primarily within biology, focusing on the intersection of mechanical forces and cellular physiology.

The main fields of study covered by Discher include Biochemistry, Genetics and Molecular Biology, and Immunology and Microbiology. Within these broad fields, their work extends into several subfields, such as Immunology, Molecular Biology, Cell Biology, Physiology, and Surgery.

Discher's research addresses a variety of scientific topics. Notable focus areas include Phagocytosis and Immune Regulation, Cellular Mechanics and Interactions, Nuclear Structure and Function, Immune cells in cancer, RNA Research and Splicing, Erythrocyte Function and Pathophysiology, and Immunotherapy and Immune Responses.

Publication venues where Discher has frequently contributed include:

  • Biophysical Journal (24 publications)
  • bioRxiv (Cold Spring Harbor Laboratory) (12 publications)
  • Cancer Research (5 publications)
  • Bioconjugate Chemistry (2 publications)
  • Journal of Cell Science (2 publications)

Prominent frequent co-authors working alongside Discher include:

  • Lawrence J. Dooling (29 collaborations)
  • Michael P. Tobin (26 collaborations)
  • Jason C. Andrechak (23 collaborations)
  • Brandon H. Hayes (20 collaborations)
  • Manasvita Vashisth (17 collaborations)

Examples of recent papers authored or co-authored by Discher are:

  • "Challenges and opportunities for the next generation of cardiovascular tissue engineering," 2022, Nature Methods
  • "Macrophage checkpoint blockade: results from initial clinical trials, binding analyses, and CD47-SIRPα structure-function," 2020, Antibody Therapeutics
  • "Macrophages show higher levels of engulfment after disruption of cis interactions between CD47 and the checkpoint receptor SIRPα," 2020, Journal of Cell Science
  • "Cooperative phagocytosis of solid tumours by macrophages triggers durable anti-tumour responses," 2023, Nature Biomedical Engineering
  • "Lipid Nanoparticle-Associated Inflammation is Triggered by Sensing of Endosomal Damage: Engineering Endosomal Escape Without Side Effects," 2024, bioRxiv (Cold Spring Harbor Laboratory)

Among recognitions received during their career are the fellowship of the American Association for the Advancement of Science awarded in 2015, and membership in the National Academy of Engineering since 2012, the latter awarded for elucidation of the effects of mechanical forces on cell physiology and stem cell development.

Best Publications

  • Matrix elasticity directs stem cell lineage specification.

    Adam J. Engler;Shamik Sen;H. Lee Sweeney;Dennis E. Discher

  • Tissue Cells Feel and Respond to the Stiffness of Their Substrate

    Dennis E. Discher;Paul Janmey;Yu Li Wang

  • Polymer vesicles : Materials science: Soft surfaces

    Dennis E. Discher;Adi Eisenberg

  • Growth Factors, Matrices, and Forces Combine and Control Stem Cells

    Dennis E. Discher;David J. Mooney;Peter W. Zandstra

  • Shape effects of filaments versus spherical particles in flow and drug delivery.

    Yan Geng;Paul Dalhaimer;Shenshen Cai;Richard Tsai

  • Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments

    Adam J. Engler;Maureen A. Griffin;Shamik Sen;Carsten G. Bönnemann

  • Nuclear lamin-A Scales With Tissue Stiffness and Enhances Matrix-Directed Differentiation

    Joe Swift;Irena L. Ivanovska;Amnon Buxboim;Takamasa Harada

  • Mesenchymal stem cell perspective: cell biology to clinical progress

    Mark F. Pittenger;Dennis E. Discher;Bruno M. Péault;Donald G. Phinney

  • Substrate Compliance versus Ligand Density in Cell on Gel Responses

    Adam Engler;Lucie Bacakova;Cynthia Newman;Alina Hategan

  • Bio-inspired, bioengineered and biomimetic drug delivery carriers

    Jin-Wook Yoo;Darrell J. Irvine;Darrell J. Irvine;Darrell J. Irvine;Dennis E. Discher;Samir Mitragotri

  • Mitotic progression following DNA damage enables pattern recognition within micronuclei

    Shane M. Harding;Joseph L. Benci;Jerome Irianto;Dennis E. Discher

  • Minimal "Self" Peptides That Inhibit Phagocytic Clearance and Enhance Delivery of Nanoparticles

    Pia L. Rodriguez;Takamasa Harada;David A. Christian;Diego A. Pantano

  • Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating

    Adam J. Engler;Christine Carag-Krieger;Colin P. Johnson;Matthew Raab

  • Physical plasticity of the nucleus in stem cell differentiation

    J. David Pajerowski;Kris Noel Dahl;Franklin L. Zhong;Paul J. Sammak

  • Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance

    Mark F. Berry;Adam J. Engler;Y. Joseph Woo;Timothy J. Pirolli

  • Nuclear lamin stiffness is a barrier to 3D-migration, but softness can limit survival

    Takamasa Harada;Joe Swift;Jerome Irianto;Jae Won Shin

  • Self-porating polymersomes of PEG-PLA and PEG-PCL: hydrolysis-triggered controlled release vesicles.

    Fariyal Ahmed;Dennis E Discher

  • Molecular Weight Dependence of Polymersome Membrane Structure, Elasticity, and Stability

    Harry Bermudez;Aaron K. Brannan;Daniel A. Hammer;Frank S. Bates

  • Biodegradable polymersomes loaded with both paclitaxel and doxorubicin permeate and shrink tumors, inducing apoptosis in proportion to accumulated drug

    Fariyal Ahmed;Refika I. Pakunlu;Aaron Brannan;Frank Bates

  • Polymer vesicles in vivo: correlations with PEG molecular weight.

    Peter J. Photos;Lucie Bacakova;Bohdana Discher;Frank S. Bates

Frequent Co-Authors

Frank S. Bates
Frank S. Bates University of Minnesota
Adam J. Engler
Adam J. Engler University of California, San Diego
David W. Speicher
David W. Speicher The Wistar Institute
Roger A. Greenberg
Roger A. Greenberg University of Pennsylvania
Michael L. Klein
Michael L. Klein Temple University
Paul A. Janmey
Paul A. Janmey University of Pennsylvania
Daniel A. Hammer
Daniel A. Hammer University of Pennsylvania
H. Lee Sweeney
H. Lee Sweeney University of Florida
Samuel A. Safran
Samuel A. Safran Weizmann Institute of Science
Catherine Picart
Catherine Picart Grenoble Alpes University

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