Adam J. Engler

Overview

Best Publications

• Matrix elasticity directs stem cell lineage specification.

  Adam J. Engler;Shamik Sen;H. Lee Sweeney;Dennis E. Discher

  15220
  Citations

• Myotubes differentiate optimally on substrates with tissue-like stiffness: pathological implications for soft or stiff microenvironments

  Adam J. Engler;Maureen A. Griffin;Shamik Sen;Carsten G. Bönnemann

  2020
  Citations

• Substrate Compliance versus Ligand Density in Cell on Gel Responses

  Adam Engler;Lucie Bacakova;Cynthia Newman;Alina Hategan

  1417
  Citations

• Stem cell fate dictated solely by altered nanotube dimension

  Seunghan Oh;Karla S. Brammer;Y. S. Julie Li;Dayu Teng

  1362
  Citations

• Preparation of Hydrogel Substrates with Tunable Mechanical Properties

  Justin R. Tse;Adam J. Engler

  1110
  Citations

• Interplay of matrix stiffness and protein tethering in stem cell differentiation

  Jessica H. Wen;Ludovic G. Vincent;Alexander Fuhrmann;Yu Suk Choi;Yu Suk Choi

  1033
  Citations

• Materials as stem cell regulators

  William L. Murphy;Todd C. McDevitt;Adam J. Engler

  994
  Citations

• Embryonic cardiomyocytes beat best on a matrix with heart-like elasticity: scar-like rigidity inhibits beating

  Adam J. Engler;Christine Carag-Krieger;Colin P. Johnson;Matthew Raab

  987
  Citations

• Intrinsic extracellular matrix properties regulate stem cell differentiation

  Gwendolen C. Reilly;Adam J. Engler

  953
  Citations

• Mesenchymal stem cell injection after myocardial infarction improves myocardial compliance

  Mark F. Berry;Adam J. Engler;Y. Joseph Woo;Timothy J. Pirolli

  883
  Citations

• Matrix stiffness drives epithelial–mesenchymal transition and tumour metastasis through a TWIST1–G3BP2 mechanotransduction pathway

  Spencer C. Wei;Laurent Fattet;Jeff H. Tsai;Yurong Guo

  880
  Citations

• Stiffness gradients mimicking in vivo tissue variation regulate mesenchymal stem cell fate.

  Justin R. Tse;Adam J. Engler

  547
  Citations

• Stem cell migration and mechanotransduction on linear stiffness gradient hydrogels

  William J. Hadden;Jennifer L. Young;Andrew W. Holle;Andrew W. Holle;Meg L. McFetridge

  504
  Citations

• Cell responses to the mechanochemical microenvironment--implications for regenerative medicine and drug delivery.

  Florian Rehfeldt;Adam J. Engler;Adam Eckhardt;Fariyal Ahmed

  493
  Citations

• Surface probe measurements of the elasticity of sectioned tissue, thin gels and polyelectrolyte multilayer films : correlations between substrate stiffness and cell adhesion

  Adam J. Engler;Ludovic Richert;Joyce Y. Wong;Catherine Picart

  446
  Citations

• Hydrogels with Time-Dependent Material Properties Enhance Cardiomyocyte Differentiation In Vitro

  Jennifer L. Young;Adam J. Engler

  400
  Citations

• Recent Advances in Extrusion-Based 3D Printing for Biomedical Applications.

  Jesse K. Placone;Adam J. Engler

  363
  Citations

• Power-Law Rheology of Isolated Nuclei with Deformation Mapping of Nuclear Substructures

  Kris Noel Dahl;Adam J. Engler;J. David Pajerowski;Dennis E. Discher

  353
  Citations

• RAP2 mediates mechanoresponses of the Hippo pathway

  Zhipeng Meng;Yunjiang Qiu;Kimberly C. Lin;Aditya Kumar

  332
  Citations

• Mesenchymal Stem Cell Durotaxis Depends on Substrate Stiffness Gradient Strength

  Ludovic G. Vincent;Yu Suk Choi;Baldomero Alonso-Latorre;Juan C. del Álamo

  327
  Citations