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Biology and Biochemistry
Ireland
2026

D-Index & Metrics

Biology and Biochemistry

D-Index
95
Citations
34761
World Ranking
1894
National Ranking
8

Research.com Recognitions

  • 2026 - Research.com Biology and Biochemistry in Ireland Leader Award
  • 2025 - Research.com Biology and Biochemistry in Ireland Leader Award
  • 2023 - Research.com Biology and Biochemistry in Ireland Leader Award
  • 2022 - Research.com Biology and Biochemistry in Ireland Leader Award

Overview

Fergal J. O'Brien is affiliated with the Royal College of Surgeons in Ireland. Their research primarily spans the field of Medicine, with a focus on Surgery, Biomedical Engineering, Biomaterials, Rheumatology, and Pulmonary and Respiratory Medicine. The scholar's work covers a range of topics including Bone Tissue Engineering Materials, Electrospun Nanofibers in Biomedical Applications, Osteoarthritis Treatment and Mechanisms, Wound Healing and Treatments, Tissue Engineering and Regenerative Medicine, Mesenchymal Stem Cell Research, and 3D Printing in Biomedical Research.

O'Brien has contributed to multiple frequent publication venues, reflecting involvement in diverse areas of biomedical science. These venues include:

  • European Urology Open Science
  • Acta Biomaterialia
  • Advanced Healthcare Materials
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biomaterials Science

Among the recent papers authored or co-authored by O'Brien are:

  • Mechanosignalling in cartilage: an emerging target for the treatment of osteoarthritis, 2021, Nature Reviews Rheumatology
  • Bone biomaterials for overcoming antimicrobial resistance: Advances in non-antibiotic antimicrobial approaches for regeneration of infected osseous tissue, 2021, Materials Today
  • 3D Printing of Multifunctional Conductive Polymer Composite Hydrogels, 2023, Advanced Functional Materials
  • 3D-Printed Gelatin Methacrylate Scaffolds with Controlled Architecture and Stiffness Modulate the Fibroblast Phenotype towards Dermal Regeneration, 2021, Polymers
  • 3D bioprinting of cartilaginous templates for large bone defect healing, 2022, Acta Biomaterialia

Frequent collaborators include Niall F. Davis, Eoghan M. Cunnane, Adrian Dervan, Ian Woods, and Caroline M. Curtin. These partnerships indicate an active engagement with researchers in related fields and interdisciplinary studies.

Best Publications

  • Biomaterials & scaffolds for tissue engineering

    Fergal J. O'Brien

  • The effect of mean pore size on cell attachment, proliferation and migration in collagen–glycosaminoglycan scaffolds for bone tissue engineering

    Ciara M. Murphy;Matthew G. Haugh;Fergal J. O'Brien;Fergal J. O'Brien

  • The effect of pore size on cell adhesion in collagen-GAG scaffolds.

    Fergal J O'Brien;B A Harley;Ioannis Yannas;Lorna J Gibson

  • Influence of freezing rate on pore structure in freeze-dried collagen-GAG scaffolds.

    Fergal J. O’Brien;Brendan A. Harley;Ioannis V. Yannas;Lorna Gibson

  • Biomaterial based modulation of macrophage polarization: A review and suggested design principles

    Rukmani Sridharan;Rukmani Sridharan;Andrew R. Cameron;Andrew R. Cameron;Daniel J. Kelly;Cathal J. Kearney

  • Understanding the effect of mean pore size on cell activity in collagen-glycosaminoglycan scaffolds

    Ciara M Murphy;Fergal J O'Brien

  • The effect of pore size on permeability and cell attachment in collagen scaffolds for tissue engineering

    Fergal J. O'Brien;Brendan A. Harley;Mary A. Waller;Ioannis V. Yannas

  • Material stiffness influences the polarization state, function and migration mode of macrophages.

    Rukmani Sridharan;Brenton Cavanagh;Andrew R. Cameron;Andrew R. Cameron;Daniel J. Kelly;Daniel J. Kelly

  • Staphylococcal Osteomyelitis: Disease Progression, Treatment Challenges, and Future Directions

    Nicola Kavanagh;Emily J. Ryan;Amro Widaa;Gillian Sexton

  • Cell-scaffold interactions in the bone tissue engineering triad.

    Ciara M Murphy;Fergal J O'Brien;David G Little;Aaron Schindeler

  • Crosslinking and mechanical properties significantly influence cell attachment, proliferation, and migration within collagen glycosaminoglycan scaffolds.

    Matthew G. Haugh;Ciara M. Murphy;Ross C. McKiernan;Cornelia Altenbuchner

  • The effect of dehydrothermal treatment on the mechanical and structural properties of collagen- GAG scaffolds.

    Matthew G. Haugh;Michael J. Jaasma;Michael J. Jaasma;Fergal J. O'Brien;Fergal J. O'Brien

  • Mesenchymal stem cell fate is regulated by the composition and mechanical properties of collagen-glycosaminoglycan scaffolds.

    Ciara M. Murphy;Amos Matsiko;Amos Matsiko;Matthew G. Haugh;Matthew G. Haugh;John P. Gleeson;John P. Gleeson

  • ADDITION OF HYDROXYAPATITE IMPROVES STIFFNESS, INTERCONNECTIVITY AND OSTEOGENIC POTENTIAL OF A HIGHLY POROUS COLLAGEN-BASED SCAFFOLD FOR BONE TISSUE REGENERATION

    JP Gleeson;NA Plunkett;FJ O’Brien

  • A biomimetic multi-layered collagen-based scaffold for osteochondral repair.

    Tanya J. Levingstone;Amos Matsiko;Glenn R. Dickson;Fergal J. O’Brien

  • Novel Freeze-Drying Methods to Produce a Range of Collagen–Glycosaminoglycan Scaffolds with Tailored Mean Pore Sizes

    Matthew G. Haugh;Ciara M. Murphy;Fergal J. O'Brien

  • A Collagen-glycosaminoglycan Scaffold Supports Adult Rat Mesenchymal Stem Cell Differentiation Along Osteogenic and Chondrogenic Routes

    Eric Farrell;Fergal J. O'Brien;Fergal J. O'Brien;Paul Doyle;Jan Fischer

  • The effect of bone microstructure on the initiation and growth of microcracks.

    Fergal J. O'Brien;David Taylor;T. Clive Lee;T. Clive Lee

  • Scaffold mean pore size influences mesenchymal stem cell chondrogenic differentiation and matrix deposition.

    Amos Matsiko;John P. Gleeson;Fergal J. O'Brien

  • Bioreactors in tissue engineering

    Niamh Plunkett;Fergal J. O'Brien

Frequent Co-Authors

Daniel J. Kelly
Daniel J. Kelly Trinity College Dublin
Andreas Heise
Andreas Heise Royal College of Surgeons in Ireland
Patrick J. Prendergast
Patrick J. Prendergast Trinity College Dublin
Brendan A.C. Harley
Brendan A.C. Harley University of Illinois at Urbana-Champaign
Valeria Nicolosi
Valeria Nicolosi Trinity College Dublin
Harrie Weinans
Harrie Weinans Utrecht University
Raymond L. Stallings
Raymond L. Stallings Royal College of Surgeons in Ireland
Timothy O'Brien
Timothy O'Brien University of Minnesota
Timothy J. Foster
Timothy J. Foster Campden BRI (United Kingdom)

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