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Biology and Biochemistry
Canada
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
81
Citations
24613
World Ranking
3876
National Ranking
124

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Canada Leader Award
  • 2014 - Fellow of the Royal Society of Canada Academy of Science
  • 2010 - Fellow of the Indian National Academy of Engineering (INAE)
  • 2007 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 2007 - Fellow of John Simon Guggenheim Memorial Foundation

Overview

Peter W. Zandstra is affiliated with the University of British Columbia in Canada. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with significant contributions to subfields such as Molecular Biology, Immunology, Oncology, Biomedical Engineering, and Surgery.

Their work covers a variety of topics, including CAR-T cell therapy research, CRISPR and Genetic Engineering, Pluripotent Stem Cells Research, Single-cell and spatial transcriptomics, 3D Printing in Biomedical Research, Immune Cell Function and Interaction, and Gene Regulatory Network Analysis.

Frequent coauthors collaborating with Peter W. Zandstra include:

  • Yale S. Michaels
  • John M. Edgar
  • Carla Zimmerman
  • Tiam Heydari
  • Ross D. Jones

They have published extensively in several venues, notably:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Cytotherapy
  • Scientific Reports
  • Nature Biotechnology
  • Cell Stem Cell

Recent papers authored or coauthored by Peter W. Zandstra include:

  • A 96-well culture platform enables longitudinal analyses of engineered human skeletal muscle microtissue strength, 2020, Scientific Reports
  • Deconvolution of clinical variance in CAR-T cell pharmacology and response, 2023, Nature Biotechnology
  • Functional arrays of human pluripotent stem cell-derived cardiac microtissues, 2020, Scientific Reports
  • Endogenous suppression of WNT signalling in human embryonic stem cells leads to low differentiation propensity towards definitive endoderm, 2021, Scientific Reports
  • DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells, 2022, Science Advances

Peter W. Zandstra has been recognized with several fellowships, including:

  • Fellow of the Royal Society of Canada, 2014, Academy of Science
  • Fellow of the Indian National Academy of Engineering (INAE), 2010
  • Fellow of the American Association for the Advancement of Science (AAAS), 2007
  • Fellow of John Simon Guggenheim Memorial Foundation, 2007

Best Publications

  • Growth Factors, Matrices, and Forces Combine and Control Stem Cells

    Dennis E. Discher;David J. Mooney;Peter W. Zandstra

  • A 17-gene stemness score for rapid determination of risk in acute leukaemia

    Stanley W. K. Ng;Amanda Mitchell;James A. Kennedy;James A. Kennedy;James A. Kennedy;Weihsu C. Chen

  • TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal

    Xaralabos Varelas;Rui Sakuma;Payman Samavarchi-Tehrani;Raheem Peerani

  • Pyrimidoindole derivatives are agonists of human hematopoietic stem cell self-renewal

    Iman Fares;Jalila Chagraoui;Yves Gareau;Stéphane Gingras

  • Control of human embryonic stem cell colony and aggregate size heterogeneity influences differentiation trajectories.

    Céline Liu Bauwens;Raheem Peerani;Sylvia Niebruegge;Kimberly A. Woodhouse

  • Reproducible, ultra high-throughput formation of multicellular organization from single cell suspension-derived human embryonic stem cell aggregates.

    Mark D. Ungrin;Chirag Joshi;Andra Nica;Céline Bauwens

  • A Microfabricated Platform to Measure and Manipulate the Mechanics of Engineered Cardiac Microtissues

    Thomas Boudou;Wesley R. Legant;Anbin Mu;Michael A. Borochin

  • Efficiency of embryoid body formation and hematopoietic development from embryonic stem cells in different culture systems.

    Stephen M. Dang;Michael Kyba;Rita Perlingeiro;George Q. Daley

  • Niche-mediated control of human embryonic stem cell self-renewal and differentiation.

    Raheem Peerani;Balaji M Rao;Celine Bauwens;Ting Yin

  • Controlled, scalable embryonic stem cell differentiation culture.

    Stephen M. Dang;Sharon Gerecht‐Nir;Sharon Gerecht‐Nir;Jinny Chen;Joseph Itskovitz‐Eldor;Joseph Itskovitz‐Eldor

  • An Alternative Splicing Switch Regulates Embryonic Stem Cell Pluripotency and Reprogramming

    Mathieu Gabut;Payman Samavarchi-Tehrani;Payman Samavarchi-Tehrani;Xinchen Wang;Valentina Slobodeniuc

  • Differential cytokine effects on primitive (CD34+CD38-) human hematopoietic cells: novel responses to Flt3-ligand and thrombopoietin.

    A L Petzer;P W Zandstra;J M Piret;C J Eaves

  • A Mass Spectrometric-Derived Cell Surface Protein Atlas

    Damaris Bausch-Fluck;Andreas Hofmann;Thomas Bock;Andreas P. Frei

  • Cytokine manipulation of primitive human hematopoietic cell self-renewal.

    P. W. Zandstra;E. Conneally;A. L. Petzer;J. M. Piret

  • Scalable production of embryonic stem cell-derived cardiomyocytes.

    Peter W. Zandstra;C. Bauwens;T. Yin;Q. Liu

  • Design and formulation of functional pluripotent stem cell-derived cardiac microtissues

    Nimalan Thavandiran;Nicole Dubois;Alexander Mikryukov;Stéphane Massé

  • The Systematic Production of Cells for Cell Therapies

    Daniel C. Kirouac;Peter W. Zandstra

  • Shear-Controlled Single-Step Mouse Embryonic Stem Cell Expansion and Embryoid Body–Based Differentiation

    Elaine Y.L. Fok;Peter W. Zandstra

  • Quality cell therapy manufacturing by design

    Yonatan Y Lipsitz;Nicholas E Timmins;Peter W Zandstra

  • A Myc enhancer cluster regulates normal and leukaemic haematopoietic stem cell hierarchies.

    Carsten Bahr;Carsten Bahr;Lisa von Paleske;Lisa von Paleske;Veli V. Uslu;Silvia Remeseiro

Frequent Co-Authors

Andras Nagy
Andras Nagy Lunenfeld-Tanenbaum Research Institute
John E. Dick
John E. Dick Princess Margaret Cancer Centre
Connie J. Eaves
Connie J. Eaves University of British Columbia
Milica Radisic
Milica Radisic University of Toronto
Guy Sauvageau
Guy Sauvageau University of Montreal
Gordon Keller
Gordon Keller University of Toronto
Eugenia Kumacheva
Eugenia Kumacheva University of Toronto
Mathieu Lupien
Mathieu Lupien Princess Margaret Cancer Centre
Christopher S. Chen
Christopher S. Chen Boston University

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