Rafael A. Irizarry

Research.com Recognitions

• 2020 - Fellow of the International Society for Computational Biology
• 2009 - COPSS Presidents' Award For his wide-ranging and highly influential contributions to the theory and methodology of statistical science that underpins the analysis of time series and genomic data; for demonstrating the essential role of statistics to the advancement of modern genomic science and biotechnology; for advancing statistical practice through publication of open-source software and participation in the core development group of Bioconductor; for his leadership of multidisciplinary scientific teams; and for his outstanding contributions to statistics as an editorial board member and mentor of students and post-doctoral fellows.
• 2009 - Fellow of the American Statistical Association (ASA)

Overview

Best Publications

• Bioconductor: open software development for computational biology and bioinformatics

  Robert C Gentleman;Vincent J Carey;Douglas M. Bates;B.M. Bolstad

  14674
  Citations

• Salmon provides fast and bias-aware quantification of transcript expression

  Rob Patro;Geet Duggal;Michael I Love;Rafael A Irizarry

  12681
  Citations

• Exploration, normalization, and summaries of high density oligonucleotide array probe level data

  Rafael A. Irizarry;Bridget Hobbs;Francois Collin;Yasmin D. Beazer-Barclay

  12580
  Citations

• A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

  Benjamin M. Bolstad;Rafael A. Irizarry;Magnus Åstrand;Terence P. Speed;Terence P. Speed

  10031
  Citations

• Summaries of Affymetrix GeneChip probe level data

  Rafael A. Irizarry;Benjamin M. Bolstad;Francois Collin;Leslie M. Cope

  5982
  Citations

• affy---analysis of Affymetrix GeneChip data at the probe level

  Laurent Gautier;Leslie Cope;Benjamin M. Bolstad;Rafael A. Irizarry

  5656
  Citations

• Minfi: A flexible and comprehensive Bioconductor package for the analysis of Infinium DNA Methylation microarrays

  Martin J. Aryee;Andrew E. Jaffe;Hector Corrada-Bravo;Christine Ladd-Acosta

  3790
  Citations

• Orchestrating high-throughput genomic analysis with Bioconductor

  Wolfgang Huber;Vincent J Carey;Robert Gentleman;Simon Anders

  3513
  Citations

• Epigenetic memory in induced pluripotent stem cells

  K. Kim;A. Doi;B. Wen;K. Ng

  2587
  Citations

• The human colon cancer methylome shows similar hypo- and hypermethylation at conserved tissue-specific CpG island shores.

  Rafael A. Irizarry;Christine Ladd-Acosta;Bo Wen;Zhijin Wu

  2500
  Citations

• Tackling the widespread and critical impact of batch effects in high-throughput data

  Jeffrey T. Leek;Robert B. Scharpf;Héctor Corrada Bravo;Héctor Corrada Bravo;David Simcha

  2387
  Citations

• A Model-Based Background Adjustment for Oligonucleotide Expression Arrays

  Zhijin Wu;Rafael A. Irizarry;Robert C Gentleman;Francisco Martinez-Murillo

  2161
  Citations

• MAGeCK enables robust identification of essential genes from genome-scale CRISPR/Cas9 knockout screens.

  Wei Li;Han Xu;Tengfei Xiao;Le Cong;Le Cong

  2042
  Citations

• A framework for oligonucleotide microarray preprocessing

  Benilton S. Carvalho;Rafael A. Irizarry

  1544
  Citations

• Differential methylation of tissue- and cancer-specific CpG island shores distinguishes human induced pluripotent stem cells, embryonic stem cells and fibroblasts.

  Akiko Doi;In Hyun Park;Bo Wen;Peter Murakami

  1361
  Citations

• The Microarray Quality Control (MAQC)-II study of common practices for the development and validation of microarray-based predictive models

  Leming Shi;Gregory Campbell;Wendell D. Jones;Fabien Campagne

  1213
  Citations

• Increased methylation variation in epigenetic domains across cancer types

  Kasper Daniel Hansen;Winston Timp;Winston Timp;Héctor Corrada Bravo;Héctor Corrada Bravo;Sarven Sabunciyan

  1204
  Citations

• Multiple-laboratory comparison of microarray platforms

  Rafael A Irizarry;Daniel Warren;Forrest Spencer;Irene F Kim

  1076
  Citations

• Accounting for cellular heterogeneity is critical in epigenome-wide association studies

  Andrew E Jaffe;Rafael A Irizarry

  1048
  Citations

• Meta-analysis of gut microbiome studies identifies disease-specific and shared responses.

  Claire Duvallet;Sean M. Gibbons;Sean M. Gibbons;Thomas Gurry;Thomas Gurry;Rafael A. Irizarry

  891
  Citations