World's Best Scientists 2026 revealed!

D-Index & Metrics

Genetics

D-Index
111
Citations
113975
World Ranking
504
National Ranking
14

Research.com Recognitions

  • 1994 - Fellow of the American Association for the Advancement of Science (AAAS)
  • 1989 - Fellow of the American Statistical Association (ASA)

Overview

Terence P. Speed is primarily affiliated with the Walter and Eliza Hall Institute of Medical Research in Australia. Their academic contributions span multiple areas within the broad field of Biochemistry, Genetics and Molecular Biology, with a significant focus on Molecular Biology, Immunology, Cancer Research, Oncology, and Genetics.

The scientist's research topics cover diverse aspects of cellular biology and cancer, including:

  • Single-cell and spatial transcriptomics
  • T-cell and B-cell Immunology
  • Cancer Genomics and Diagnostics
  • Cancer Immunotherapy and Biomarkers
  • Immunotherapy and Immune Responses
  • Gene expression and cancer classification
  • Immune Cell Function and Interaction

Terence P. Speed has contributed to several recent publications across leading scientific journals. Notable papers include:

  • Discrete tissue microenvironments instruct diversity in resident memory T cell function and plasticity, 2021, Nature Immunology
  • Intratumoral CD8+ T cells with a tissue-resident memory phenotype mediate local immunity and immune checkpoint responses in breast cancer, 2023, Cancer Cell
  • scClassify: sample size estimation and multiscale classification of cells using single and multiple reference, 2020, Molecular Systems Biology
  • Strategies to enable large-scale proteomics for reproducible research, 2020, Nature Communications
  • Changes in ferrous iron and glutathione promote ferroptosis and frailty in aging Caenorhabditis elegans, 2020, eLife

The frequent co-authors collaborating with Terence P. Speed include Marie Trussart, Susan N. Christo, Luke C. Gandolfo, Laura K. Mackay, and Ramyar Molania. These collaborative relationships reflect sustained partnerships in advancing research in related scientific domains.

Scientific findings from this research have been published predominantly in these venues:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Nature Communications
  • Nature Immunology
  • Cancer Cell
  • eLife

In addition to journal articles, Terence P. Speed has contributed to book publications, including a title released by Springer Science+Business Media: Computational Advances in Bio and Medical Sciences (2021).

The scientist has been recognized by professional organizations with fellowships from the American Statistical Association (1989) and the American Association for the Advancement of Science (1994).

Best Publications

  • A comparison of normalization methods for high density oligonucleotide array data based on variance and bias

    Benjamin M. Bolstad;Rafael A. Irizarry;Magnus Åstrand;Terence P. Speed;Terence P. Speed

  • Integrated Genomic Analysis Identifies Clinically Relevant Subtypes of Glioblastoma Characterized by Abnormalities in PDGFRA, IDH1, EGFR, and NF1

    Roel G. W. Verhaak;Katherine A. Hoadley;Elizabeth Purdom;Victoria Wang

  • Integrated genomic analyses of ovarian carcinoma

    D. Bell;A. Berchuck;M. Birrer;J. Chien

  • Comprehensive genomic characterization defines human glioblastoma genes and core pathways

    Roger McLendon;Allan Friedman;Darrell Bigner;Erwin G. Van Meir

  • Summaries of Affymetrix GeneChip probe level data

    Rafael A. Irizarry;Benjamin M. Bolstad;Francois Collin;Leslie M. Cope

  • Normalization for cDNA microarray data: a robust composite method addressing single and multiple slide systematic variation

    Yee Hwa Yang;Sandrine Dudoit;Percy Luu;David M. Lin

  • A collection of breast cancer cell lines for the study of functionally distinct cancer subtypes

    Richard M. Neve;Richard M. Neve;Koei Chin;Jane Fridlyand;Jennifer Yeh

  • Comparison of discrimination methods for the classification of tumors using gene expression data

    Sandrine Dudoit;Jane Fridlyand;Terence P Speed

  • Normalization of cDNA microarray data.

    Gordon K Smyth;Terry Speed;Terry Speed

  • International network of cancer genome projects

    Thomas J. Hudson;Thomas J. Hudson;Warwick Anderson;Axel Aretz;Anna D. Barker

  • STATISTICAL METHODS FOR IDENTIFYING DIFFERENTIALLY EXPRESSED GENES IN REPLICATED cDNA MICROARRAY EXPERIMENTS

    Sandrine Dudoit;Y ee Hwa Yang;Matthew J. Callow;Terence P. Speed

  • Normalization of RNA-seq data using factor analysis of control genes or samples

    Davide Risso;John Ngai;Terence P Speed;Sandrine Dudoit

  • GOstat: find statistically overrepresented Gene Ontologies within a group of genes

    Tim Beißbarth;Terence P. Speed

  • Design issues for cDNA microarray experiments.

    Yee Hwa Yang;Terry Speed

  • Summarizing and correcting the GC content bias in high-throughput sequencing

    Yuval Benjamini;Terence P. Speed

  • Single-cell profiling of breast cancer T cells reveals a tissue-resident memory subset associated with improved prognosis

    Peter Savas;Balaji Virassamy;Chengzhong Ye;Agus Salim;Agus Salim

  • Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

    Tarjei S. Mikkelsen;Tarjei S. Mikkelsen;Matthew J. Wakefield;Bronwen Aken;Chris T. Amemiya

  • Statistical issues in cDNA microarray data analysis.

    Gordon K. Smyth;Yee Hwa Yang;Terry Speed;Terry Speed

  • Comparison of Methods for Image Analysis on cDNA Microarray Data

    Yee Hwa Yang;Michael J Buckley;Sandrine Dudoit;Terence P Speed

  • Integrated genomic analyses of ovarian carcinoma

    D. Bell;A. Berchuck;M. Birrer;J. Chien

Frequent Co-Authors

Melanie Bahlo
Melanie Bahlo Walter and Eliza Hall Institute of Medical Research
Simon J. Foote
Simon J. Foote Australian National University
Anthony T. Papenfuss
Anthony T. Papenfuss Walter and Eliza Hall Institute of Medical Research
Sherene Loi
Sherene Loi Peter MacCallum Cancer Centre
Mark D. Robinson
Mark D. Robinson University of Zurich
Paul T. Spellman
Paul T. Spellman Oregon Health & Science University
Gordon K. Smyth
Gordon K. Smyth Walter and Eliza Hall Institute of Medical Research
Helmut Butzkueven
Helmut Butzkueven Monash University
Joe W. Gray
Joe W. Gray Oregon Health & Science University
John Ngai
John Ngai University of California, Berkeley

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