World's Best Scientists 2026 revealed!

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Biology and Biochemistry

D-Index
74
Citations
17563
World Ranking
5666
National Ranking
2684

Research.com Recognitions

  • 2019 - Member of the National Academy of Engineering For entrepreneurship and development of cell lines, cell media, and testing technologies for regenerative medicine and biopharma products.

Overview

Mary Pat Moyer is affiliated with Incell Corporation in the United States. Their research primarily falls within the field of Medicine, with substantial work in subfields such as Surgery, Molecular Biology, Oncology, Gastroenterology, and Pharmacology.

Their research topics include:

  • Colorectal Cancer Screening and Detection
  • Genetic factors in colorectal cancer
  • Colorectal Cancer Treatments and Studies
  • Gastroesophageal reflux and treatments
  • Helicobacter pylori-related gastroenterology studies
  • Esophageal and GI Pathology
  • Phosphodiesterase function and regulation

Recent publication venues for Moyer's work comprise Preprints.org, International Journal of Molecular Sciences, International Journal of Biological Sciences, Cancer Prevention Research, and bioRxiv (Cold Spring Harbor Laboratory).

Frequent coauthors include Martin Tobi, Benita L. McVicker, Noreen F. Rossi, Michael Lawson, and Harvinder Talwar.

Key papers authored recently include:

  • Proteomic Characterization of Colorectal Cancer Cells versus Normal-Derived Colon Mucosa Cells: Approaching Identification of Novel Diagnostic Protein Biomarkers in Colorectal Cancer, 2020, International Journal of Molecular Sciences
  • Suppression of Colon Tumorigenesis in Mutant Apc Mice by a Novel PDE10 Inhibitor that Reduces Oncogenic β-Catenin, 2021, Cancer Prevention Research
  • The Low-density Lipoprotein Receptor-related Protein 6 Pathway in the Treatment of Intestinal Barrier Dysfunction Induced by Hypoxia and Intestinal Microbiota through the Wnt/β-catenin Pathway, 2022, International Journal of Biological Sciences
  • Intramammary infection of bovine H5N1 influenza virus in ferrets leads to transmission in suckling neonates, 2024, bioRxiv (Cold Spring Harbor Laboratory)
  • Predicting Regression of Barrett's Esophagus-Can All the King's Men Put It Together Again?, 2024, Biomolecules

Moyer's work shows a recurrent engagement with colorectal cancer mechanisms and therapies, molecular pathways affecting gastrointestinal health, and emerging infectious disease models.

In 2019, Moyer was recognized as a Member of the National Academy of Engineering for their contributions to entrepreneurship and the development of cell lines, cell media, and testing technologies pertinent to regenerative medicine and biopharma products.

Best Publications

  • Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha.

    Marcia L. Moss;S.-L. Catherine Jin;Marcos E. Milla;William Burkhart

  • Target genes of beta-catenin-T cell-factor/lymphoid-enhancer-factor signaling in human colorectal carcinomas.

    B. Mann;M. Gelos;A. Siedow;M. L. Hanski

  • Fusobacterium nucleatum Increases Proliferation of Colorectal Cancer Cells and Tumor Development in Mice by Activating Toll-Like Receptor 4 Signaling to Nuclear Factor−κB, and Up-regulating Expression of MicroRNA-21

    Yongzhi Yang;Yongzhi Yang;Wenhao Weng;Wenhao Weng;Junjie Peng;Leiming Hong

  • Long non-coding RNA CCAL regulates colorectal cancer progression by activating Wnt/β-catenin signalling pathway via suppression of activator protein 2α

    Yanlei Ma;Yanlei Ma;Yongzhi Yang;Feng Wang;Feng Wang;Mary Pat Moyer

  • Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2)

    A Arlt;I Bauer;C Schafmayer;J Tepel

  • NCM460, a normal human colon mucosal epithelial cell line.

    Mary Pat Moyer;Lawrence A. Manzano;Ronald L. Merriman;Jay S. Stauffer

  • MicroRNA-135b Promotes Cancer Progression by Acting as a Downstream Effector of Oncogenic Pathways in Colon Cancer

    Nicola Valeri;Chiara Braconi;Pierluigi Gasparini;Claudio Murgia

  • Isolation of a complementary DNA encoding a chitinase with structural homology to a bifunctional lysozyme/chitinase

    J. P. Metraux;William Burkhart;Mary Moyer;Sandra Dincher

  • Anthocyanin-Rich Extract From Aronia meloncarpa E. Induces a Cell Cycle Block in Colon Cancer but Not Normal Colonic Cells

    Minnie Malik;Cuiwei Zhao;Norberta Schoene;M Monica Guisti

  • Isolation of complementary DNA clones encoding pathogenesis-related proteins P and Q, two acidic chitinases from tobacco.

    George Payne;Patricia Ahl;Mary Moyer;Andrew Harper

  • Aurora-a is essential for the tumorigenic capacity and chemoresistance of colorectal cancer stem cells.

    Patrizia Cammareri;Alessandro Scopelliti;Matilde Todaro;Vincenzo Eterno

  • Pentagastrin stimulates in vitro growth of normal and malignant human colon epithelial cells

    Kenneth R. Sirinek;Barry A. Levine;Mary Pat Moyer

  • Metalloproteinases and Transforming Growth Factor-α Mediate Substance P-induced Mitogen-activated Protein Kinase Activation and Proliferation in Human Colonocytes

    Hon-Wai Koon;Dezheng Zhao;Xi Na;Mary P. Moyer

  • Differential gene expression in colon carcinoma cells and tissues detected with a cDNA array.

    Steffen Backert;Marcos Gelos;Ursula Kobalz;Marie‐Luise Hanski

  • Signal Transduction Pathways Mediating Neurotensin-stimulated Interleukin-8 Expression in Human Colonocytes

    Dezheng Zhao;Andrew C. Keates;Sabina Kuhnt-Moore;Mary P. Moyer

  • HIV inactivation in a bone allograft.

    James T. Mellonig;Annamarie B. Prewett;Mary Pat Moyer

  • Epithelial TNF Receptor Signaling Promotes Mucosal Repair in Inflammatory Bowel Disease.

    Emily M. Bradford;Emily M. Bradford;Stacy H. Ryu;Ajay Pal Singh;Goo Lee

  • Sulindac Selectively Inhibits Colon Tumor Cell Growth by Activating the cGMP/PKG Pathway to Suppress Wnt/β-Catenin Signaling

    Nan Li;Yaguang Xi;Heather N. Tinsley;Evrim Gurpinar

  • Rotating-wall vessel coculture of small intestine as a prelude to tissue modeling: aspects of simulated microgravity.

    Thomas J. Goodwin;William F. Schroeder;David A. Wolf;Mary Pat Moyer

  • Biotin uptake by human colonic epithelial NCM460 cells: a carrier-mediated process shared with pantothenic acid.

    Hamid M. Said;Alvaro Ortiz;Alvaro Ortiz;Eric McCloud;Eric McCloud;David Dyer;David Dyer

Frequent Co-Authors

Charalabos Pothoulakis
Charalabos Pothoulakis University of California, Los Angeles
Surinder K. Batra
Surinder K. Batra University of Nebraska Medical Center
Hamid M. Said
Hamid M. Said University of California, Irvine
William E. Grizzle
William E. Grizzle University of Alabama at Birmingham
Thomas E. Adrian
Thomas E. Adrian Northwestern University
Enrique Rozengurt
Enrique Rozengurt University of California, Los Angeles
Bent Honoré
Bent Honoré Aarhus University
Jian Yu
Jian Yu University of Pittsburgh
Claire E. Hulsebosch
Claire E. Hulsebosch The University of Texas Health Science Center at Houston
Carla Oliveira
Carla Oliveira University of Porto

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