D-Index & Metrics Best Publications

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 59 Citations 21,976 88 World Ranking 5879 National Ranking 2764

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Enzyme
  • Amino acid

The scientist’s investigation covers issues in ADAM17 Protein, Molecular biology, Biochemistry, Metalloproteinase and ADAM Proteins. Roy A. Black has researched ADAM17 Protein in several fields, including Tumor necrosis factor alpha, ADAM15, ADAM9 and Cell biology. His Tumor necrosis factor alpha research integrates issues from Sheddase and Ectodomain.

His Molecular biology research is multidisciplinary, incorporating perspectives in Receptor, Protease and Cytokine. Many of his studies on Biochemistry apply to Interleukin as well. In his study, Cell activation and Kinase is inextricably linked to Transmembrane protein, which falls within the broad field of ADAM Proteins.

His most cited work include:

  • A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells (2698 citations)
  • An Essential Role for Ectodomain Shedding in Mammalian Development (1424 citations)
  • A Novel Proteolytic Cleavage Involved in Notch Signaling: The Role of the Disintegrin-Metalloprotease TACE (1001 citations)

What are the main themes of his work throughout his whole career to date?

His primary scientific interests are in Biochemistry, Molecular biology, Metalloproteinase, Tumor necrosis factor alpha and Cell biology. The Molecular biology study combines topics in areas such as Receptor, Transmembrane protein, ADAM17 Protein and Proteolysis. His research in ADAM17 Protein tackles topics such as ADAM9 which are related to areas like ADAM10.

His primary area of study in Metalloproteinase is in the field of Disintegrin. The study incorporates disciplines such as Metalloprotease inhibitor, Cell, Sheddase and Cytokine in addition to Tumor necrosis factor alpha. His Cell biology course of study focuses on Ectodomain and Amphiregulin.

He most often published in these fields:

  • Biochemistry (37.86%)
  • Molecular biology (28.16%)
  • Metalloproteinase (23.30%)

What were the highlights of his more recent work (between 2012-2021)?

  • Fatty acid (8.74%)
  • Biochemistry (37.86%)
  • Membrane (9.71%)

In recent papers he was focusing on the following fields of study:

Roy A. Black spends much of his time researching Fatty acid, Biochemistry, Membrane, Amino acid and Vesicle. His Fatty acid study combines topics in areas such as Yield, Cellular life, Flocculation and Peptide. RNA and Decanoic acid are the primary areas of interest in his Biochemistry study.

His RNA research focuses on Protocell and how it relates to Prebiotic, Salt, Divalent, Biophysics and Oligonucleotide. His studies in Vesicle integrate themes in fields like Glycine and Alanine. The various areas that Roy A. Black examines in his Glycine study include Leucine, Isoleucine and Dipeptide.

Between 2012 and 2021, his most popular works were:

  • Sclerostin is expressed in articular cartilage but loss or inhibition does not affect cartilage remodeling during aging or following mechanical injury. (74 citations)
  • Local Hydrogel Release of Recombinant TIMP-3 Attenuates Adverse Left Ventricular Remodeling After Experimental Myocardial Infarction (69 citations)
  • Nucleobases bind to and stabilize aggregates of a prebiotic amphiphile, providing a viable mechanism for the emergence of protocells (61 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Enzyme
  • Amino acid

His primary areas of study are Membrane, Protocell, Biochemistry, RNA and Internal medicine. His work deals with themes such as Amino acid and Fatty acid, which intersect with Membrane. His Amino acid research incorporates elements of Prebiotic, Vesicle, Biophysics, Salt and Divalent.

Roy A. Black regularly ties together related areas like Oligonucleotide in his Fatty acid studies. The concepts of his Internal medicine study are interwoven with issues in Lesion, Endocrinology, Knee Joint and Bone tissue. Micelle, Decanoic acid, Ribose and Amphiphile are fields of study that intersect with his Nucleobase research.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

Roy A. Black;Charles T. Rauch;Carl J. Kozlosky;Jacques J. Peschon.
Nature (1997)

3820 Citations

An Essential Role for Ectodomain Shedding in Mammalian Development

Jacques J. Peschon;Jennifer L. Slack;Pranitha Reddy;Kim L. Stocking.
Science (1998)

1852 Citations

A Novel Proteolytic Cleavage Involved in Notch Signaling: The Role of the Disintegrin-Metalloprotease TACE

Christel Brou;Frédérique Logeat;Neetu Gupta;Christine Bessia.
Molecular Cell (2000)

1394 Citations

Evidence That Tumor Necrosis Factor α Converting Enzyme Is Involved in Regulated α-Secretase Cleavage of the Alzheimer Amyloid Protein Precursor

Joseph D. Buxbaum;Kang-Nian Liu;Yuxia Luo;Jennifer L. Slack.
Journal of Biological Chemistry (1998)

1257 Citations

Viral inhibition of inflammation. Cowpox virus encodes an inhibitor of the interleukin 1β converting enzyme.

Caroline A. Ray;Roy A. Black;Shirley R. Kronheim;Teresa A. Greenstreet.
Cell (1992)

1247 Citations

Functional Analysis of the Domain Structure of Tumor Necrosis Factor-α Converting Enzyme

Pranhitha Reddy;Jennifer L. Slack;Raymond Davis;Douglas Pat Cerretti.
Journal of Biological Chemistry (2000)

633 Citations

ADAMs: focus on the protease domain

Roy A Black;Judith M White.
Current Opinion in Cell Biology (1998)

600 Citations

Tumor Necrosis Factor-α Converting Enzyme (TACE) Regulates Epidermal Growth Factor Receptor Ligand Availability

Susan Wohler Sunnarborg;C. Leann Hinkle;Mary Stevenson;William E. Russell.
Journal of Biological Chemistry (2002)

483 Citations

Tumor necrosis factor-α converting enzyme

Roy A Black.
The International Journal of Biochemistry & Cell Biology (2002)

465 Citations

Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor.

R A Black;S R Kronheim;M Cantrell;M C Deeley.
Journal of Biological Chemistry (1988)

463 Citations

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