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D-Index & Metrics

Biology and Biochemistry

D-Index
63
Citations
24659
World Ranking
9981
National Ranking
4372

Overview

Roy A. Black is affiliated with Amgen in the United States. Their research spans the fields of Physics and Astronomy as well as Biochemistry, Genetics and Molecular Biology. The subfields of study in which they have contributed include Astronomy and Astrophysics, Molecular Biology, Cellular and Molecular Neuroscience, Materials Chemistry, and Environmental Chemistry.

The main topics of their research focus on the Origins and Evolution of Life, Protein Structure and Dynamics, RNA and protein synthesis mechanisms, Photoreceptor and optogenetics research, Enzyme Structure and Function, Photosynthetic Processes and Mechanisms, and Methane Hydrates and Related Phenomena.

Their frequent co-authors include Zachary R. Cohen, Sarah L. Keller, David C. Catling, Zoe R. Todd, and Caitlin E. Cornell.

Roy A. Black has published extensively in a number of scientific journals. Their main publication venues are Langmuir, ChemBioChem, Biophysical Journal, ACS Earth and Space Chemistry, and The Journal of Physical Chemistry B.

Recent papers authored by or co-authored with Roy A. Black include the following:

  • Growth of Prebiotically Plausible Fatty Acid Vesicles Proceeds in the Presence of Prebiotic Amino Acids, Dipeptides, Sugars, and Nucleic Acid Components, 2022, Langmuir
  • Plausible Sources of Membrane-Forming Fatty Acids on the Early Earth: A Review of the Literature and an Estimation of Amounts, 2022, ACS Earth and Space Chemistry
  • A Step toward Molecular Evolution of RNA: Ribose Binds to Prebiotic Fatty Acid Membranes, and Nucleosides Bind Better than Individual Bases Do, 2020, ChemBioChem
  • Binding of Dipeptides to Fatty Acid Membranes Explains Their Colocalization in Protocells but Does Not Select for Them Relative to Unjoined Amino Acids, 2021, The Journal of Physical Chemistry B
  • Prebiotic Protocell Membranes Retain Encapsulated Contents during Flocculation, and Phospholipids Preserve Encapsulation during Dehydration, 2022, Langmuir

Best Publications

  • A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells

    Roy A. Black;Charles T. Rauch;Carl J. Kozlosky;Jacques J. Peschon

  • An Essential Role for Ectodomain Shedding in Mammalian Development

    Jacques J. Peschon;Jennifer L. Slack;Pranitha Reddy;Kim L. Stocking

  • Molecular cloning of the interleukin-1 beta converting enzyme

    Douglas Pat Cerretti;Carl J. Kozlosky;Bruce Mosley;Nicole Nelson

  • A Novel Proteolytic Cleavage Involved in Notch Signaling: The Role of the Disintegrin-Metalloprotease TACE

    Christel Brou;Frédérique Logeat;Neetu Gupta;Christine Bessia

  • Viral inhibition of inflammation. Cowpox virus encodes an inhibitor of the interleukin 1β converting enzyme.

    Caroline A. Ray;Roy A. Black;Shirley R. Kronheim;Teresa A. Greenstreet

  • Evidence That Tumor Necrosis Factor α Converting Enzyme Is Involved in Regulated α-Secretase Cleavage of the Alzheimer Amyloid Protein Precursor

    Joseph D. Buxbaum;Kang-Nian Liu;Yuxia Luo;Jennifer L. Slack

  • Functional Analysis of the Domain Structure of Tumor Necrosis Factor-α Converting Enzyme

    Pranhitha Reddy;Jennifer L. Slack;Raymond Davis;Douglas Pat Cerretti

  • ADAMs: focus on the protease domain

    Roy A Black;Judith M White

  • Tumor necrosis factor-alpha converting enzyme (TACE) regulates epidermal growth factor receptor ligand availability.

    Susan Wohler Sunnarborg;C. Leann Hinkle;Mary Stevenson;William E. Russell

  • Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor.

    R A Black;S R Kronheim;M Cantrell;M C Deeley

  • Tumor necrosis factor-α converting enzyme

    Roy A Black

  • Crystal structure of the catalytic domain of human tumor necrosis factor-alpha-converting enzyme.

    Klaus Maskos;Carlos Fernandez-Catalan;Robert Huber;Gleb P. Bourenkov

  • Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase.

    Hitoshi Mizutani;Norman Schechter;Gerald Lazarus;Roy A. Black

  • Activation of interleukin- 1β by a co-induced protease

    Roy A. Black;Shirley R. Kronheim;Paul R. Sleath

  • Cleavage of interleukin 1 beta (IL-1 beta) precursor to produce active IL-1 beta by a conserved extracellular cysteine protease from Streptococcus pyogenes.

    Vivek Kapur;Mark W. Majesky;Ling Ling Li;Roy A. Black

  • A metalloprotease inhibitor blocks shedding of the IL-6 receptor and the p60 TNF receptor.

    J Müllberg;F H Durie;C Otten-Evans;M R Alderson

  • A metalloprotease inhibitor blocks shedding of the 80-kD TNF receptor and TNF processing in T lymphocytes.

    Paul D. Crowe;Barbara N. Walter;Kendall M. Mohler;Carol Otten-Evans

  • Metalloproteases regulate T-cell proliferation and effector function via LAG-3

    Nianyu Li;Yao Wang;Karen Forbes;Kate M Vignali

  • ADAM10 is a principal 'sheddase' of the low-affinity immunoglobulin E receptor CD23

    Gisela Weskamp;Jill W Ford;Jamie Sturgill;Steve Martin

  • Human keratinocytes produce but do not process pro-interleukin-1 (IL-1) beta. Different strategies of IL-1 production and processing in monocytes and keratinocytes.

    H Mizutani;R Black;T S Kupper

Frequent Co-Authors

Stuart J. Frank
Stuart J. Frank University of Alabama at Birmingham
Douglas Pat Cerretti
Douglas Pat Cerretti Amgen (United States)
Klaus Maskos
Klaus Maskos Proteros biostructures GmbH
Carl J. March
Carl J. March Amgen (United States)
Jacques J. Peschon
Jacques J. Peschon Amgen (United States)
Julius Adler
Julius Adler University of Wisconsin–Madison
Zach W. Hall
Zach W. Hall University of California, San Francisco
Wolfram Bode
Wolfram Bode Max Planck Society
Thomas S. Kupper
Thomas S. Kupper Brigham and Women's Hospital
Jason A. Burdick
Jason A. Burdick University of Colorado Boulder

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