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Biology and Biochemistry

D-Index
100
Citations
37462
World Ranking
1516
National Ranking
854

Medicine

D-Index
99
Citations
36919
World Ranking
8583
National Ranking
4422

Research.com Recognitions

  • 2008 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

Thomas S. Kupper is affiliated with Brigham and Women's Hospital in the United States. Their research primarily spans the fields of Medicine and Immunology and Microbiology, with a focus on Immunology, Dermatology, Oncology, Molecular Biology, and Epidemiology. These subfields provide a foundation for investigating complex interactions within immune responses and skin-related diseases.

The main topics of Thomas S. Kupper's work include:

  • Immune Cell Function and Interaction
  • Cutaneous lymphoproliferative disorders research
  • Immunotherapy and Immune Responses
  • T-cell and B-cell Immunology
  • CAR-T cell therapy research
  • Dermatology and Skin Diseases
  • Lymphoma Diagnosis and Treatment

Their recent notable publications include:

  • "Streptococcal pyrogenic exotoxin B cleaves GSDMA and triggers pyroptosis," 2022, Nature
  • "Peripheral host T cells survive hematopoietic stem cell transplantation and promote graft-versus-host disease," 2020, Journal of Clinical Investigation
  • "Epicutaneous immunization with modified vaccinia Ankara viral vectors generates superior T cell immunity against a respiratory viral challenge," 2021, npj Vaccines
  • "Assessing the generation of tissue resident memory T cells by vaccines," 2023, Nature Reviews. Immunology
  • "Molecular analysis of primary melanoma T cells identifies patients at risk for metastatic recurrence," 2020, Nature Cancer

The publication venues where Thomas S. Kupper most frequently publishes are:

  • Journal of Investigative Dermatology
  • bioRxiv (Cold Spring Harbor Laboratory)
  • SSRN Electronic Journal
  • Nature
  • Nature Cancer

Thomas S. Kupper has collaborated with several frequent co-authors, including:

  • Rachael A. Clark
  • Youdong Pan
  • Jessica E. Teague
  • Claire A. Stingley
  • Nicole R. LeBoeuf

Aside from journal articles, Thomas S. Kupper has authored book publications, such as "Bewusst im Paradies: Kitsch und Reflexivität," published by Transcript Verlag in 2022.

Throughout their career, Thomas S. Kupper has been recognized as a Fellow of the American Association for the Advancement of Science (AAAS), an honor awarded in 2008.

Best Publications

  • Identification of cells initiating human melanomas

    Tobias Schatton;George F. Murphy;Natasha Y. Frank;Kazuhiro Yamaura

  • Interleukin 6 is expressed in high levels in psoriatic skin and stimulates proliferation of cultured human keratinocytes.

    Rachel M. Grossman;James Krueger;Debra Yourish;Angela Granelli-Piperno

  • Skin infection generates non-migratory memory CD8+ T(RM) cells providing global skin immunity.

    Xiaodong Jiang;Rachael A. Clark;Luzheng Liu;Amy J. Wagers

  • Immune surveillance in the skin: mechanisms and clinical consequences

    Thomas S. Kupper;Robert C. Fuhlbrigge

  • The Vast Majority of CLA+ T Cells Are Resident in Normal Skin

    Rachael A. Clark;Benjamin Chong;Nina Mirchandani;Nooshin K. Brinster

  • Survival of tissue-resident memory T cells requires exogenous lipid uptake and metabolism

    Youdong Pan;Tian Tian;Chang Ook Park;Serena Y. Lofftus

  • Cutaneous lymphocyte antigen is a specialized form of PSGL-1 expressed on skin-homing T cells

    Robert C. Fuhlbrigge;J. David Kieffer;Dieter Armerding;Thomas S. Kupper

  • Melanoma cell-intrinsic PD-1 receptor functions promote tumor growth

    Sonja Kleffel;Christian Posch;Steven R Barthel;Hansgeorg Mueller;Hansgeorg Mueller

  • Inflammatory Skin Diseases, T Cells, and Immune Surveillance

    Caroline Robert;Thomas S. Kupper

  • Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice.

    Hong Xu;J. A. Gonzalo;Y. St. Pierre;I. R. Williams

  • Human skin is protected by four functionally and phenotypically discrete populations of resident and recirculating memory T cells.

    Rei Watanabe;Ahmed Gehad;Chao Yang;Laura L. Scott

  • Sézary syndrome and mycosis fungoides arise from distinct T-cell subsets: a biologic rationale for their distinct clinical behaviors

    James J. Campbell;Rachael A. Clark;Rei Watanabe;Thomas S. Kupper

  • Human Epidermal Langerhans Cells Maintain Immune Homeostasis in Skin by Activating Skin Resident Regulatory T Cells

    Julien Seneschal;Rachael A. Clark;Ahmed Gehad;Clare M. Baecher-Allan

  • The emerging role of resident memory T cells in protective immunity and inflammatory disease

    Chang Ook Park;Thomas S Kupper

  • Robust tumor immunity to melanoma mediated by interleukin-9-producing T cells

    Rahul Purwar;Christoph Schlapbach;Sheng Xiao;Hong Soon Kang

  • Human keratinocytes contain mRNA indistinguishable from monocyte interleukin 1 alpha and beta mRNA. Keratinocyte epidermal cell-derived thymocyte-activating factor is identical to interleukin 1.

    T S Kupper;D W Ballard;A O Chua;J S McGuire

  • Integrin α2β1 (VLA-2) mediates reorganization and contraction of collagen matrices by human cells

    James A. Schiro;Bosco M.C. Chan;William T. Roswit;Paul D. Kassner

  • Rapid and specific conversion of precursor interleukin 1 beta (IL-1 beta) to an active IL-1 species by human mast cell chymase.

    Hitoshi Mizutani;Norman Schechter;Gerald Lazarus;Roy A. Black

  • Interleukin 1 gene expression in cultured human keratinocytes is augmented by ultraviolet irradiation

    T S Kupper;A O Chua;P Flood;J McGuire

  • Response to Comment on “The Vast Majority of CLA+ T Cells Are Resident in Normal Skin”

    Rachael A. Clark;Thomas S. Kupper

Frequent Co-Authors

Rachael A. Clark
Rachael A. Clark Brigham and Women's Hospital
Robert C. Fuhlbrigge
Robert C. Fuhlbrigge University of Colorado Anschutz Medical Campus
George F. Murphy
George F. Murphy Brigham and Women's Hospital
Harlan Robins
Harlan Robins Adaptive Biotechnologies (United States)
Richard A.F. Clark
Richard A.F. Clark Stony Brook University
Ifor R. Williams
Ifor R. Williams Emory University
Martin C. Mihm
Martin C. Mihm Brigham and Women's Hospital
Caroline Robert
Caroline Robert University of Paris-Saclay
James G. Krueger
James G. Krueger Rockefeller University
David A. Jones
David A. Jones Australian National University

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