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Ifor R. Williams

Ifor R. Williams

D-Index & Metrics

Immunology

D-Index
73
Citations
20975
World Ranking
2126
National Ranking
1033

Overview

Ifor R. Williams is affiliated with Emory University in the United States and has contributed to research primarily within the fields of immunology, epidemiology, molecular biology, infectious diseases, and cardiology and cardiovascular medicine. Their work spans a range of topics centered on immune system function and interactions, host-pathogen relationships, and microbial impact on health.

Their research addresses themes such as:

  • Gut microbiota and health
  • IL-33, ST2, and ILC pathways
  • Immune cell function and interaction
  • Clostridium difficile and Clostridium perfringens research
  • Mycobacterium research and diagnosis
  • Microscopic colitis
  • Respiratory viral infections research

Recent publications include:

  • Acetate differentially regulates IgA reactivity to commensal bacteria, 2021, Nature
  • This Week in Science, 2020, Science
  • This Week in Science, 2020, Science
  • This Week in Science, 2020, Science
  • This Week in Science, 2020, Science

The dominant publication venues for Ifor R. Williams's work are:

  • Science (51 publications)
  • Nature (1 publication)
  • Traffic (1 publication)
  • Science Immunology (1 publication)

Collaboration is a significant component of their research output. Frequent co-authors include:

  • Gemma Alderton (35 collaborations)
  • Brent Grocholski (29 collaborations)
  • Phil Szuromi (27 collaborations)
  • Marc S. Lavine (23 collaborations)
  • Pamela J. Hines (23 collaborations)

The combination of these research topics, published work, and collaborative networks highlights a scientific career focused on immune mechanisms in relation to microbial environments and infectious disease, with multidisciplinary approaches spanning basic and applied biomedical sciences.

Best Publications

  • FoxOs are critical mediators of hematopoietic stem cell resistance to physiologic oxidative stress.

    Zuzana Tothova;Zuzana Tothova;Ramya Kollipara;Brian J. Huntly;Benjamin H. Lee;Benjamin H. Lee

  • Lamina propria macrophages and dendritic cells differentially induce regulatory and interleukin 17-producing T cell responses.

    Timothy L Denning;Yi-chong Wang;Seema R Patel;Ifor R Williams

  • MOZ-TIF2, but not BCR-ABL, confers properties of leukemic stem cells to committed murine hematopoietic progenitors

    Brian J.P. Huntly;Hirokazu Shigematsu;Kenji Deguchi;Benjamin H. Lee

  • Microfold (M) cells: important immunosurveillance posts in the intestinal epithelium

    Neil A. Mabbott;David S. Donaldson;Hiroshi Ohno;Ifor R. Williams

  • FLT3 internal tandem duplication mutations associated with human acute myeloid leukemias induce myeloproliferative disease in a murine bone marrow transplant model.

    Louise M. Kelly;Qing Liu;Jeffrey L. Kutok;Ifor R. Williams

  • Leukocytosis and resistance to septic shock in intercellular adhesion molecule 1-deficient mice.

    Hong Xu;J. A. Gonzalo;Y. St. Pierre;I. R. Williams

  • JAM-A regulates permeability and inflammation in the intestine in vivo.

    Mike G. Laukoetter;Porfirio Nava;Winston Y. Lee;Eric A. Severson

  • Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype

    Joseph D. Growney;Hirokazu Shigematsu;Zhe Li;Benjamin H. Lee

  • Deletion of TLR5 results in spontaneous colitis in mice.

    Matam Vijay-Kumar;Catherine J. Sanders;Rebekah T. Taylor;Amrita Kumar

  • Mouse model of Noonan syndrome reveals cell type– and gene dosage–dependent effects of Ptpn11 mutation

    Toshiyuki Araki;M Golam Mohi;Fraz A Ismat;Roderick T Bronson

  • PML/RARα and FLT3-ITD induce an APL-like disease in a mouse model

    Louise M. Kelly;Jeffrey L. Kutok;Ifor R. Williams;Christina L. Boulton

  • Stat5 is essential for the myelo- and lymphoproliferative disease induced by TEL/JAK2.

    Juerg Schwaller;Evan Parganas;Demin Wang;Danielle Cain

  • CX3CR1 regulates intestinal macrophage homeostasis, bacterial translocation and colitogenic TH17 responses in mice

    Oscar Medina-Contreras;Duke Geem;Oskar Laur;Ifor R Williams

  • Prognostic, therapeutic, and mechanistic implications of a mouse model of leukemia evoked by Shp2 (PTPN11) mutations

    M. Golam Mohi;Ifor R. Williams;Charles R. Dearolf;Gordon Chan

  • Conditional expression of oncogenic K-ras from its endogenous promoter induces a myeloproliferative disease

    Iris T. Chan;Jeffery L. Kutok;Ifor R. Williams;Sarah Cohen

  • RANKL Is Necessary and Sufficient to Initiate Development of Antigen-Sampling M Cells in the Intestinal Epithelium

    Kathryn A. Knoop;Nachiket Kumar;Betsy R. Butler;Senthilkumar K. Sakthivel

  • Lipoxin A4 Analogs Attenuate Induction of Intestinal Epithelial Proinflammatory Gene Expression and Reduce the Severity of Dextran Sodium Sulfate-Induced Colitis

    Andrew T. Gewirtz;Lauren S. Collier-Hyams;Andrew N. Young;Torsten Kucharzik

  • CCR6-mediated dendritic cell activation of pathogen-specific T cells in Peyer's patches.

    Rosa Maria Salazar-Gonzalez;Jan H. Niess;David J. Zammit;Rajesh Ravindran

  • Autoantigen-specific interactions with CD4(+) thymocytes control mature medullary thymic epithelial cell cellularity

    Magali Irla;Stéphanie Hugues;Jason Gill;Takeshi Nitta

  • Transformation of hematopoietic cell lines to growth‐factor independence and induction of a fatal myelo‐ and lymphoproliferative disease in mice by retrovirally transduced TEL/JAK2 fusion genes

    J Schwaller;J Frantsve;J Aster;I R Williams

  • MOZ-TIF2, but Not BCR-ABL, Confers Properties of Leukemic Stem Cells to Committed Murine Hematopoietic Progenitors.

    Brian J.P. Huntly;Hirokazu Shigematzu;Kenji Deguchi;Benjamin Lee

Frequent Co-Authors

D. Gary Gilliland
D. Gary Gilliland Fred Hutchinson Cancer Research Center
Jeffery L. Kutok
Jeffery L. Kutok Epizyme (United States)
Thomas S. Kupper
Thomas S. Kupper Brigham and Women's Hospital
Koichi Akashi
Koichi Akashi Kyushu University
Andrew T. Gewirtz
Andrew T. Gewirtz Georgia State University
Neil A. Mabbott
Neil A. Mabbott University of Edinburgh
Hideo Yagita
Hideo Yagita Juntendo University
Wolfram Domschke
Wolfram Domschke University of Münster
Jon C. Aster
Jon C. Aster Harvard Medical School

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