World's Best Scientists 2026 revealed!

D-Index & Metrics

Biology and Biochemistry

D-Index
101
Citations
40576
World Ranking
1430
National Ranking
816

Medicine

D-Index
101
Citations
40586
World Ranking
7926
National Ranking
4124

Overview

Jeffery L. Kutok is affiliated with Epizyme in the United States. Their research spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine, with a focus on Molecular Biology, Pulmonary and Respiratory Medicine, Hematology, Oncology, and Genetics.

The main topics of Kutok's work include:

  • Protein Degradation and Inhibitors
  • Cancer-related gene regulation
  • Ubiquitin and proteasome pathways
  • Cancer Immunotherapy and Biomarkers
  • Lung Cancer Treatments and Mutations
  • Chronic Lymphocytic Leukemia Research
  • Chronic Myeloid Leukemia Treatments

Notable recent publications authored or coauthored by Kutok cover a variety of cancer-related research areas. These include:

  • EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes, 2023, Cancer Research
  • 352 Updated clinical data from the squamous cell carcinoma of the head and neck (SCCHN) expansion cohort of an ongoing Ph1/1b Study of eganelisib (formerly IPI-549) in combination with nivolumab, 2020, Regular and Young Investigator Award Abstracts
  • Duvelisib Eliminates CLL B Cells, Impairs CLL-Supporting Cells, and Overcomes Ibrutinib Resistance in a Xenograft Model, 2023, Clinical Cancer Research
  • Pharmacologic Inhibition of the Histone Methyltransferase SETD2 with EZM0414 As a Novel Therapeutic Strategy in Relapsed or Refractory Multiple Myeloma and Diffuse Large B-Cell Lymphoma, 2021, Blood
  • EZH2 synergizes with BRD4-NUT to drive NUT carcinoma growth through silencing of key tumor suppressor genes, 2023, bioRxiv (Cold Spring Harbor Laboratory)

Frequent coauthors collaborating with Kutok include:

  • Alejandra Raimondi
  • Yeying Huang
  • R. Taylor Durall
  • Nhi M. Luong
  • Hans J. Hertzler

Publications by Kutok are commonly found in the following venues:

  • Cancer Research
  • Clinical Cancer Research
  • Regular and Young Investigator Award Abstracts
  • Blood
  • Cancer Cell

Best Publications

  • Diffuse large B-cell lymphoma outcome prediction by gene-expression profiling and supervised machine learning

    Margaret A. Shipp;Ken N. Ross;Pablo Tamayo;Andrew P. Weng

  • Regulation of the Germinal Center Response by MicroRNA-155

    To-Ha Thai;Dinis Pedro Calado;Stefano Casola;K. Mark Ansel

  • Integrative analysis reveals selective 9p24.1 amplification, increased PD-1 ligand expression, and further induction via JAK2 in nodular sclerosing Hodgkin lymphoma and primary mediastinal large B-cell lymphoma

    Michael R. Green;Stefano Monti;Scott J. Rodig;Przemyslaw Juszczynski

  • PI3Kγ is a molecular switch that controls immune suppression

    Megan M. Kaneda;Karen S. Messer;Natacha Ralainirina;Hongying Li

  • The molecular signature of mediastinal large B-cell lymphoma differs from that of other diffuse large B-cell lymphomas and shares features with classical Hodgkin lymphoma

    Kerry J. Savage;Stefano Monti;Jeffery L. Kutok;Giorgio Cattoretti

  • Molecular profiling of diffuse large B-cell lymphoma identifies robust subtypes including one characterized by host inflammatory response

    Stefano Monti;Kerry J. Savage;Jeffery L. Kutok;Friedrich Feuerhake

  • Overcoming resistance to checkpoint blockade therapy by targeting PI3Kγ in myeloid cells

    Olivier De Henau;Matthew Rausch;David Winkler;Luis Felipe Campesato

  • BRAF Mutations Are Sufficient to Promote Nevi Formation and Cooperate with p53 in the Genesis of Melanoma

    E.Elizabeth Patton;Hans R. Widlund;Jeffery L. Kutok;Kamden R. Kopani;Kamden R. Kopani

  • Mesenchyme Forkhead 1 (FOXC2) plays a key role in metastasis and is associated with aggressive basal-like breast cancers

    Sendurai A. Mani;Jing Yang;Jing Yang;Mary Brooks;Gunda Schwaninger

  • B cell receptor signal strength determines B cell fate.

    Stefano Casola;Stefano Casola;Kevin L Otipoby;Marat Alimzhanov;Sibille Humme;Sibille Humme

  • tp53 mutant zebrafish develop malignant peripheral nerve sheath tumors

    Stéphane Berghmans;Ryan D. Murphey;Erno Wienholds;Donna Neuberg

  • Myc-induced T cell leukemia in transgenic zebrafish.

    David M. Langenau;David Traver;Adolfo A. Ferrando;Jeffery L. Kutok

  • Acute myeloid leukemia induced by graded reduction of a lineage-specific transcription factor, PU.1.

    Frank Rosenbauer;Katharina Wagner;Jeffery L Kutok;Hiromi Iwasaki

  • H3K79 Methylation Profiles Define Murine and Human MLL-AF4 Leukemias

    Andrei V. Krivtsov;Zhaohui Feng;Madeleine E. Lemieux;Joerg Faber

  • Loss of Runx1 perturbs adult hematopoiesis and is associated with a myeloproliferative phenotype

    Joseph D. Growney;Hirokazu Shigematsu;Zhe Li;Benjamin H. Lee

  • In vivo tracking of T cell development, ablation, and engraftment in transgenic zebrafish.

    David M. Langenau;Adolfo A. Ferrando;David Traver;Jeffery L. Kutok

  • Mouse model of Noonan syndrome reveals cell type– and gene dosage–dependent effects of Ptpn11 mutation

    Toshiyuki Araki;M Golam Mohi;Fraz A Ismat;Roderick T Bronson

  • Haploinsufficiency for ribosomal protein genes causes selective activation of p53 in human erythroid progenitor cells

    Shilpee Dutt;Anupama Narla;Anupama Narla;Anupama Narla;Katherine Lin;Ann Mullally

  • JAGGED1 expression is associated with prostate cancer metastasis and recurrence

    Sandro Santagata;Francesca Demichelis;Alberto Riva;Sooryanarayana Varambally

  • TNF family member B cell-activating factor (BAFF) receptor-dependent and -independent roles for BAFF in B cell physiology.

    Yoshiteru Sasaki;Stefano Casola;Jeffery L. Kutok;Klaus Rajewsky

Frequent Co-Authors

Donna Neuberg
Donna Neuberg Harvard University
Scott J. Rodig
Scott J. Rodig Harvard University
Margaret A. Shipp
Margaret A. Shipp Harvard University
Jon C. Aster
Jon C. Aster Harvard Medical School
Lewis B. Silverman
Lewis B. Silverman Harvard University
A. Thomas Look
A. Thomas Look Harvard University
Stephen E. Sallan
Stephen E. Sallan Harvard University
D. Gary Gilliland
D. Gary Gilliland Fred Hutchinson Cancer Research Center
Todd R. Golub
Todd R. Golub Harvard University
Ifor R. Williams
Ifor R. Williams Emory University

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