Didier Merlin

Overview

Best Publications

• Orally delivered thioketal nanoparticles loaded with TNF-α–siRNA target inflammation and inhibit gene expression in the intestines

  D. Scott Wilson;Guillaume Dalmasso;Lixin Wang;Shanthi V. Sitaraman

  708
  Citations

• Edible ginger-derived nanoparticles: A novel therapeutic approach for the prevention and treatment of inflammatory bowel disease and colitis-associated cancer.

  Mingzhen Zhang;Emilie Viennois;Meena Prasad;Yunchen Zhang

  675
  Citations

• Concomitant Activation of the JAK/STAT, PI3K/AKT, and ERK Signaling Is Involved in Leptin-Mediated Promotion of Invasion and Migration of Hepatocellular Carcinoma Cells

  Neeraj K. Saxena;Dipali Sharma;Xiaokun Ding;Songbai Lin

  569
  Citations

• Temporal and Spatial Analysis of Clinical and Molecular Parameters in Dextran Sodium Sulfate Induced Colitis

  Yutao Yan;Vasantha Kolachala;Guillaume Dalmasso;Hang Nguyen

  474
  Citations

• 193 Orally Delivered Thioketal-Nanoparticles Loaded With TNFα-SiRNA Target Inflammation and Inhibit Gene Expression in the Intestines

  David S. Wilson;Guillaume Dalmasso;Lixin Wang;Shanthi V. Sitaraman

  442
  Citations

• Dextran Sodium Sulfate (DSS) Induces Colitis in Mice by Forming Nano-Lipocomplexes with Medium-Chain-Length Fatty Acids in the Colon

  Hamed Laroui;Sarah A. Ingersoll;Sarah A. Ingersoll;Hong Chun Liu;Hong Chun Liu;Mark T. Baker

  397
  Citations

• Targeted deletion of metalloproteinase 9 attenuates experimental colitis in mice: central role of epithelial-derived MMP.

  Florencia E Castaneda;Baljit Walia;Matam Vijay-Kumar;Neal R Patel

  319
  Citations

• Edible Ginger-derived Nano-lipids Loaded with Doxorubicin as a Novel Drug-delivery Approach for Colon Cancer Therapy.

  Mingzhen Zhang;Bo Xiao;Bo Xiao;Huan Wang;Moon Kwon Han

  313
  Citations

• hPepT1 transports muramyl dipeptide, activating NF-κB and stimulating IL-8 secretion in human colonic Caco2/bbe cells

  Stephan R. Vavricka;Mark W. Musch;Jonathan E. Chang;Yasushi Nakagawa

  282
  Citations

• Bidirectional Crosstalk between Leptin and Insulin-like Growth Factor-I Signaling Promotes Invasion and Migration of Breast Cancer Cells via Transactivation of Epidermal Growth Factor Receptor

  Neeraj K. Saxena;La Tonia Taliaferro-Smith;Brandi B. Knight;Didier Merlin

  280
  Citations

• IL-6 induces NF-kappa B activation in the intestinal epithelia.

  Lixin Wang;Baljit Walia;John Evans;Andrew T. Gewirtz

  275
  Citations

• Salmonella typhimurium induces epithelial IL-8 expression via Ca2+-mediated activation of the NF-κB pathway

  Andrew T. Gewirtz;Anjali S. Rao;Peter O. Simon;Didier Merlin

  262
  Citations

• Dietary Emulsifier–Induced Low-Grade Inflammation Promotes Colon Carcinogenesis

  Emilie Viennois;Didier Merlin;Didier Merlin;Andrew T. Gewirtz;Benoit Chassaing

  261
  Citations

• PepT1-mediated epithelial transport of dipeptides and cephalexin is enhanced by luminal leptin in the small intestine

  Marion Buyse;Françoise Berlioz;Sandra Guilmeau;Annick Tsocas

  260
  Citations

• Drug-Loaded Nanoparticles Targeted to the Colon With Polysaccharide Hydrogel Reduce Colitis in a Mouse Model

  Hamed Laroui;Guillaume Dalmasso;Hang Thi Thu Nguyen;Yutao Yan

  259
  Citations

• Plant derived edible nanoparticles as a new therapeutic approach against diseases

  Mingzhen Zhang;Emilie Viennois;Changlong Xu;Didier Merlin

  257
  Citations

• Neutrophil-epithelial crosstalk at the intestinal lumenal surface mediated by reciprocal secretion of adenosine and IL-6

  Shanthi V. Sitaraman;Didier Merlin;Lixin Wang;Michelle Wong

  228
  Citations

• Oral administration of ginger-derived nanolipids loaded with siRNA as a novel approach for efficient siRNA drug delivery to treat ulcerative colitis.

  Mingzhen Zhang;Xiaoyu Wang;Moon Kwon Han;James F Collins

  226
  Citations

• Colonic epithelial hPepT1 expression occurs in inflammatory bowel disease: Transport of bacterial peptides influences expression of MHC class 1 molecules

  Didier Merlin;Mustapha Si-Tahar;Shanthi V. Sitaraman;Karen Eastburn

  220
  Citations

• Colonic leptin: source of a novel proinflammatory cytokine involved in IBD

  Shanthi Sitaraman;Xia Liu;Laetitia Charrier;Li Hao Gu

  220
  Citations