2004 - Fellow of the American Association for the Advancement of Science (AAAS)
Wayne I. Lencer mainly focuses on Cell biology, Immunoglobulin G, Immunology, Neonatal Fc receptor and Cholera toxin. His Cell biology study combines topics from a wide range of disciplines, such as Adenosine and Cell membrane. Wayne I. Lencer has included themes like Molecular biology, Computational biology and Immunotherapy in his Immunoglobulin G study.
His Neonatal Fc receptor research also works with subjects such as
Wayne I. Lencer focuses on Cell biology, Cholera toxin, Biochemistry, Endoplasmic reticulum and Immunology. His Cell biology research is multidisciplinary, relying on both Transcytosis, Receptor and Cell membrane. His work carried out in the field of Cholera toxin brings together such families of science as Lipid raft, Endocytosis, Ganglioside and Toxin.
In his study, which falls under the umbrella issue of Biochemistry, Membrane is strongly linked to Biophysics. His Endoplasmic reticulum study combines topics in areas such as Innate immune system and Signal transduction. His Neonatal Fc receptor study integrates concerns from other disciplines, such as Lamina propria, Molecular biology and MHC class I.
Cell biology, Transcytosis, Endosome, Unfolded protein response and Endoplasmic reticulum are his primary areas of study. The concepts of his Cell biology study are interwoven with issues in Endocytic cycle and Membrane transport. His Membrane transport research incorporates themes from Golgi apparatus, Cell, Cholera toxin, Drug delivery and Flow cytometry.
His research in Cholera toxin focuses on subjects like Membrane curvature, which are connected to Glycolipid. His research in Endosome intersects with topics in Transport protein, Compartment and Cell polarity. He has researched Receptor in several fields, including Neonatal Fc receptor, Inflammatory bowel disease and Immune complex.
His primary areas of investigation include Cell biology, Transcytosis, Endosome, Cholera toxin and Cell polarity. Many of his studies involve connections with topics such as Inflammation and Cell biology. His study on Transcytosis also encompasses disciplines like
His Endosome research integrates issues from Albumin and Hepatocyte. The Cholera toxin study combines topics in areas such as Membrane, Membrane bending, Membrane curvature, Internalization and Entry into host. His Cell polarity research includes elements of Transport protein, Vesicular transport protein, Receptor-mediated endocytosis and Cellular differentiation.
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Protein disulfide isomerase acts as a redox-dependent chaperone to unfold cholera toxin.
Billy Tsai;Chiara Rodighiero;Wayne I. Lencer;Tom A. Rapoport.
Role of the glycocalyx in regulating access of microparticles to apical plasma membranes of intestinal epithelial cells: implications for microbial attachment and oral vaccine targeting.
A Frey;K T Giannasca;R Weltzin;P J Giannasca.
Journal of Experimental Medicine (1996)
Receptor specific transepithelial transport of therapeutics
Richard S. Blumberg;Neil E. Simister;Wayne I. Lencer.
Gangliosides are receptors for murine polyoma virus and SV40.
Billy Tsai;Joanna M. Gilbert;Thilo Stehle;Wayne Lencer.
The EMBO Journal (2003)
MHC Class I-Related Neonatal Fc Receptor for IgG Is Functionally Expressed in Monocytes, Intestinal Macrophages, and Dendritic Cells
Xiaoping Zhu;Gang Meng;Bonny L. Dickinson;Xiaotong Li.
Journal of Immunology (2001)
Human Neonatal Fc Receptor Mediates Transport of IgG into Luminal Secretions for Delivery of Antigens to Mucosal Dendritic Cells
Masaru Yoshida;Steven M Claypool;Jessica S Wagner;Emiko Mizoguchi.
Myosin light chain phosphorylation regulates barrier function by remodeling tight junction structure
Le Shen;Eric D. Black;Edwina D. Witkowski;Wayne I. Lencer.
Journal of Cell Science (2006)
Bidirectional FcRn-dependent IgG transport in a polarized human intestinal epithelial cell line
Bonny L. Dickinson;Kamran Badizadegan;Zhen Wu;Jeremy C. Ahouse.
Journal of Clinical Investigation (1999)
Pulmonary delivery of an erythropoietin Fc fusion protein in non-human primates through an immunoglobulin transport pathway
Alan J. Bitonti;Jennifer A. Dumont;Susan C. Low;Robert T. Peters.
Proceedings of the National Academy of Sciences of the United States of America (2004)
Receptor-mediated Immunoglobulin G Transport Across Mucosal Barriers in Adult Life: Functional Expression of FcRn in the Mammalian Lung
Gerburg M. Spiekermann;Patricia W. Finn;Patricia W. Finn;E. Sally Ward;Jennifer Dumont.
Journal of Experimental Medicine (2002)
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