What is he best known for?
The fields of study he is best known for:
- Gene
- Enzyme
- Immune system
The scientist’s investigation covers issues in Biochemistry, Escherichia coli, Cholera toxin, Protein subunit and Enterotoxin.
His work in the fields of Cell membrane, Protein disulfide-isomerase, Protein structure and Thioredoxin overlaps with other areas such as In vivo.
He has researched Escherichia coli in several fields, including Pathogenic bacteria, Microbiology and Mechanism of action.
His Cholera toxin research is multidisciplinary, relying on both Transcytosis, Epithelial polarity, Molecular biology, Cell biology and KDEL Motif.
Timothy R. Hirst combines subjects such as Periplasmic space, Mutant and Vibrio cholerae with his study of Protein subunit.
He mostly deals with Heat-labile enterotoxin in his studies of Enterotoxin.
His most cited work include:
- Protein disulphide isomerase: building bridges in protein folding (633 citations)
- Membrane traffic and the cellular uptake of cholera toxin. (223 citations)
- Immune modulation by the cholera-like enterotoxins: from adjuvant to therapeutic (198 citations)
What are the main themes of his work throughout his whole career to date?
His primary areas of investigation include Enterotoxin, Escherichia coli, Cholera toxin, Heat-labile enterotoxin and Microbiology.
His study in Enterotoxin is interdisciplinary in nature, drawing from both Glycoprotein, Biogenesis, In vitro and Immunogenicity.
His Escherichia coli study is concerned with the larger field of Biochemistry.
His Cholera toxin research integrates issues from Toxin, KDEL, Immune system and Ganglioside.
The concepts of his Heat-labile enterotoxin study are interwoven with issues in Virology, Vibrio, Adjuvant, Peptide sequence and Stereochemistry.
The various areas that Timothy R. Hirst examines in his Microbiology study include Secretion, Antibody, Escherichia coli Proteins and Vibrio cholerae.
He most often published in these fields:
- Enterotoxin (39.83%)
- Escherichia coli (37.29%)
- Cholera toxin (35.59%)
What were the highlights of his more recent work (between 2000-2012)?
- Cholera toxin (35.59%)
- Molecular biology (32.20%)
- Enterotoxin (39.83%)
In recent papers he was focusing on the following fields of study:
His primary scientific interests are in Cholera toxin, Molecular biology, Enterotoxin, Microbiology and Protein subunit.
His Cholera toxin research includes themes of Toxin, Biochemistry, Mutant, Immune system and Vibrio cholerae.
His studies in Molecular biology integrate themes in fields like Apoptosis, CD8, Receptor, Ganglioside and Cytotoxic T cell.
His Enterotoxin research entails a greater understanding of Escherichia coli.
His work is dedicated to discovering how Microbiology, Immunoglobulin G are connected with Lymphocyte proliferation, Strangles and Streptococcus equi and other disciplines.
His Protein subunit study integrates concerns from other disciplines, such as Epitope and Pentamer.
Between 2000 and 2012, his most popular works were:
- Cholera toxin: a paradigm for multi-functional engagement of cellular mechanisms (Review). (151 citations)
- A mutant cholera toxin B subunit that binds GM1- ganglioside but lacks immunomodulatory or toxic activity. (93 citations)
- F-actin dynamics control segregation of the TCR signaling cascade to clustered lipid rafts. (88 citations)
In his most recent research, the most cited papers focused on:
- Gene
- Enzyme
- Immune system
His main research concerns Cholera toxin, Enterotoxin, Microbiology, Heat-labile enterotoxin and Adjuvant.
His biological study spans a wide range of topics, including Protein subunit and Biochemistry.
His Biochemistry study combines topics in areas such as Jurkat cells, Dendritic cell and CD8.
His Enterotoxin research is multidisciplinary, incorporating elements of Toxin and Vibrio cholerae.
His Microbiology study deals with Immunoglobulin G intersecting with Streptococcus equi, Vaccination and Strangles.
His study ties his expertise on Immune system together with the subject of Heat-labile enterotoxin.
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