Randall K. Holmes

Overview

Best Publications

• Shiga and Shiga-like toxins.

  Alison D. O'Brien;Randall K. Holmes

  1010
  Citations

• Two toxin-converting phages from Escherichia coli O157:H7 strain 933 encode antigenically distinct toxins with similar biologic activities.

  N A Strockbine;L R Marques;J W Newland;H W Smith

  836
  Citations

• Nucleotide sequence analysis and comparison of the structural genes for Shiga-like toxin I and Shiga-like toxin II encoded by bacteriophages from Escherichia coli 933

  Matthew P. Jackson;Roger J. Neill;Alison D. O'Brien;Randall K. Holmes

  562
  Citations

• Cloning and sequencing of the genes for Shiga toxin from Shigella dysenteriae type 1.

  Nancy A. Strockbine;Matthew Jackson;Lawrence Sung;Randall Holmes

  396
  Citations

• Cloning and sequencing of a Shiga-like toxin type II variant from Escherichia coli strain responsible for edema disease of swine.

  D L Weinstein;M P Jackson;J E Samuel;R K Holmes

  395
  Citations

• Characterization of hapR, a positive regulator of the Vibrio cholerae HA/protease gene hap, and its identification as a functional homologue of the Vibrio harveyi luxR gene.

  Michael G. Jobling;Randall K. Holmes

  369
  Citations

• Membrane traffic and the cellular uptake of cholera toxin.

  Wayne I. Lencer;Timothy R. Hirst;Randall K. Holmes

  324
  Citations

• Nucleotide sequence analysis of the structural genes for Shiga-like toxin I encoded by bacteriophage 933J from Escherichia coli.

  Matthew P. Jackson;John W. Newland;Randall K. Holmes;Alison D. O'Brien

  297
  Citations

• Characterization of monoclonal antibodies against Shiga-like toxin from Escherichia coli.

  Nancy A. Strockbine;Lilian R. M. Marques;Randall K. Holmes;Alison D. O'brien

  294
  Citations

• Gangliosides That Associate with Lipid Rafts Mediate Transport of Cholera and Related Toxins from the Plasma Membrane to Endoplasmic Reticulm

  Yukako Fujinaga;Anne A. Wolf;Chiara Rodighiero;Heidi Wheeler

  293
  Citations

• Ganglioside Structure Dictates Signal Transduction by Cholera Toxin and Association with Caveolae-like Membrane Domains in Polarized Epithelia

  Anne A. Wolf;Michael G. Jobling;Susan Wimer-Mackin;Margaret Ferguson-Maltzman

  290
  Citations

• Targeting of cholera toxin and Escherichia coli heat labile toxin in polarized epithelia: role of COOH-terminal KDEL.

  W.I. Lencer;C. Constable;S. Moe;M.G. Jobling

  287
  Citations

• Biology and Molecular Epidemiology of Diphtheria Toxin and the tox Gene

  Randall K. Holmes

  273
  Citations

• Structural Characterization of the SARS-Coronavirus Spike S Fusion Protein Core

  Brian Tripet;Megan W. Howard;Michael Jobling;Randall K. Holmes

  269
  Citations

• Cloning of Shiga-like toxin structural genes from a toxin converting phage of Escherichia coli

  John W. Newland;Nancy A. Strockbine;Steven F. Miller;Alison D. O'Brien

  237
  Citations

• Analysis of structure and function of the B subunit of cholera toxin by the use of site-directed mutagenesis.

  M. G. Jobling;R. K. Holmes

  235
  Citations

• The 1.25 A resolution refinement of the cholera toxin B-pentamer: evidence of peptide backbone strain at the receptor-binding site.

  Ethan A Merritt;Peter Kuhn;Steve Sarfaty;Jarrod L Erbe

  217
  Citations

• Iron-dependent regulation of diphtheria toxin and siderophore expression by the cloned Corynebacterium diphtheriae repressor gene dtxR in C. diphtheriae C7 strains.

  M P Schmitt;R K Holmes

  216
  Citations

• Characterization of an iron-dependent regulatory protein (IdeR) of Mycobacterium tuberculosis as a functional homolog of the diphtheria toxin repressor (DtxR) from Corynebacterium diphtheriae

  M P Schmitt;M Predich;L Doukhan;I Smith

  216
  Citations

• Structural basis for the activation of cholera toxin by human ARF6-GTP.

  Claire J. O'Neal;Michael G. Jobling;Randall K. Holmes;Wim G. J. Hol

  205
  Citations