World's Best Scientists 2026 revealed!

D-Index & Metrics

Chemistry

D-Index
116
Citations
43434
World Ranking
604
National Ranking
255

Biology and Biochemistry

D-Index
116
Citations
43842
World Ranking
760
National Ranking
479

Overview

Robert S. Hodges was affiliated with the University of Colorado Denver in the United States. Their research spanned multiple fields related to chemistry and medicine, focusing particularly on specialized areas within these domains.

The primary fields of study associated with Hodges included:

  • Chemistry
  • Medicine

Their subfields of study highlighted the scientist's focus on advanced analytical and biological techniques, including:

  • Spectroscopy
  • Molecular Biology
  • Pulmonary and Respiratory Medicine
  • Radiology, Nuclear Medicine and Imaging

Hodges' main research topics reflected a combination of analytical techniques and disease-specific studies:

  • Mass Spectrometry Techniques and Applications
  • Protein Structure and Dynamics
  • Analytical Chemistry and Chromatography
  • Prostate Cancer Treatment and Research
  • Radiopharmaceutical Chemistry and Applications

The scientist contributed to peer-reviewed literature with papers published in notable venues. These frequent publication venues included:

  • Protein Science
  • Neoplasia

Two recent publications exemplify the range of topics they addressed:

  • "Deuteration of nonexchangeable protons on proteins affects their thermal stability, side-chain dynamics, and hydrophobicity" (2020) published in Protein Science
  • "Overcoming prostate cancer drug resistance with a novel organosilicon small molecule" (2021) published in Neoplasia

The scientist collaborated with several researchers during their career. Frequent co-authors included:

  • Parker J. Nichols
  • Isaac Falconer
  • Aaron Griffin
  • Colin T. Mant
  • C. James McKnight

Overall, Robert S. Hodges contributed to the understanding of protein characteristics through spectroscopy and mass spectrometry as well as advancing research in prostate cancer treatment and radiopharmaceutical chemistry. Their interdisciplinary approach integrated chemical analysis methods with medical applications.

Best Publications

  • 1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects.

    David S. Wishart;Colin G. Bigam;Arne Holm;Robert S. Hodges

  • New hydrophilicity scale derived from high-performance liquid chromatography peptide retention data: correlation of predicted surface residues with antigenicity and X-ray-derived accessible sites.

    J. M. R. Parker;D. Guo;R. S. Hodges

  • The Duchenne muscular dystrophy gene product is localized in sarcolemma of human skeletal muscle

    Elizabeth E. Zubrzycka-Gaarn;Dennis E. Bulman;George Karpati;Arthur H. M. Burghes

  • Role of Peptide Hydrophobicity in the Mechanism of Action of α-Helical Antimicrobial Peptides

    Yuxin Chen;Michael T. Guarnieri;Adriana I. Vasil;Michael L. Vasil

  • Synthesis of a model protein of defined secondary and quaternary structure. Effect of chain length on the stabilization and formation of two-stranded alpha-helical coiled-coils.

    S Y Lau;A K Taneja;R S Hodges

  • Effect of trifluoroethanol on protein secondary structure: an NMR and CD study using a synthetic actin peptide.

    F. D. Sonnichsen;J. E. Van Eyk;R. S. Hodges;B. D. Sykes

  • Rational Design of α-Helical Antimicrobial Peptides with Enhanced Activities and Specificity/Therapeutic Index

    Yuxin Chen;Colin T. Mant;Susan W. Farmer;Robert E. W. Hancock

  • 1H, 13C and 15N random coil NMR chemical shifts of the common amino acids. I. Investigations of nearest-neighbor effects

    Unknown

  • Effects of net charge and the number of positively charged residues on the biological activity of amphipathic α-helical cationic antimicrobial peptides

    Ziqing Jiang;Adriana I. Vasil;John D. Hale;Robert E. W. Hancock

  • Relationship of sidechain hydrophobicity and alpha-helical propensity on the stability of the single-stranded amphipathic alpha-helix.

    Oscar D. Monera;Terrance J. Sereda;Nian E. Zhou;Cyril M. Kay

  • Synthetic model proteins. Positional effects of interchain hydrophobic interactions on stability of two-stranded alpha-helical coiled-coils.

    N E Zhou;C M Kay;R S Hodges

  • Protein denaturation with guanidine hydrochloride or urea provides a different estimate of stability depending on the contributions of electrostatic interactions

    Oscar D. Monera;Cyril M. Kay;Robert S. Hodges

  • Lateral mobility of proteins in liquid membranes revisited.

    Y. Gambin;R. Lopez-Esparza;M. Reffay;E. Sierecki

  • Designing Heterodimeric Two-stranded α-Helical Coiled-coils EFFECTS OF HYDROPHOBICITY AND α-HELICAL PROPENSITY ON PROTEIN FOLDING, STABILITY, AND SPECIFICITY

    Jennifer R. Litowski;Jennifer R. Litowski;Robert S. Hodges;Robert S. Hodges

  • Effects of side-chain characteristics on stability and oligomerization state of a de novo-designed model coiled-coil: 20 amino acid substitutions in position "d".

    Brian Tripet;Kurt Wagschal;Pierre Lavigne;Colin T. Mant

  • Effect of chain length on the formation and stability of synthetic alpha-helical coiled coils.

    Jeffrey Y. Su;Robert S. Hodges;Cyril M. Kay

  • Breakdown and Release of Myofilament Proteins During Ischemia and Ischemia/Reperfusion in Rat Hearts Identification of Degradation Products and Effects on the pCa-Force Relation

    Jennifer E. Van Eyk;Francis Powers;William Law;Catherine Larue

  • Dissociation of antimicrobial and hemolytic activities in cyclic peptide diastereomers by systematic alterations in amphipathicity.

    Leslie H. Kondejewski;Masood Jelokhani-Niaraki;Susan W. Farmer;Bruce Lix

  • Mapping of a second actin-tropomyosin and a second troponin C binding site within the C terminus of troponin I, and their importance in the Ca2+-dependent regulation of muscle contraction.

    Brian Tripet;Jennifer E Van Eyk;Robert S Hodges

  • A diminished role for hydrogen bonds in antifreeze protein binding to ice.

    Heman Chao;Michael E. Houston;Robert S. Hodges;Cyril M. Kay

  • Tropomyosin: Amino Acid Sequence and Coiled-Coil Structure

    R. S. Hodges;J. Sodek;L. B. Smillie;L. Jurasek

Frequent Co-Authors

Cyril M. Kay
Cyril M. Kay University of Alberta
Brian D. Sykes
Brian D. Sykes University of Alberta
Ronald N. McElhaney
Ronald N. McElhaney University of Alberta
Ruthven N.A.H. Lewis
Ruthven N.A.H. Lewis University of Alberta
Robert E. W. Hancock
Robert E. W. Hancock University of British Columbia
Frank D. Sönnichsen
Frank D. Sönnichsen Kiel University
David S. Wishart
David S. Wishart University of Alberta
Lawrence B. Smillie
Lawrence B. Smillie University of Alberta
Peter L. Davies
Peter L. Davies Queen's University
Pamela A. Sokol
Pamela A. Sokol University of Calgary

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