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William F. DeGrado
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Chemistry
USA
2026

D-Index & Metrics

Discipline name D-Index World Ranking Current World Ranking National Ranking Current National Ranking Publications Citations
Chemistry 136 244 219 116 93 722 64450
Biology and Biochemistry 136 339 305 228 202 731 65422

William F. DeGrado publications per year

The chart shows the history of publications by William F. DeGrado between 1980 and 2026, highlighting the no. of papers published in each year and offering an overview of the publication velocity of this scholar. William F. DeGrado published across 47 years, from 1980 to 2026, averaging 17.5 papers a year. Output peaked at 38 publications in 2005. 28 of the 824 publications appeared in the last two years.

No. of publications
10 20 30
Bar chart. Horizontal axis: year, 1980 to 2026. Vertical axis: number of publications, 0 to 38. Peak 38 publications in 2005. 1980: 4 publications 1981: 2 publications 1982: 3 publications 1983: 1 publication 1984: 3 publications 1985: 5 publications 1986: 4 publications 1987: 6 publications 1988: 4 publications 1989: 8 publications 1990: 8 publications 1991: 4 publications 1992: 14 publications 1993: 12 publications 1994: 21 publications 1995: 9 publications 1996: 27 publications 1997: 18 publications 1998: 15 publications 1999: 18 publications 2000: 15 publications 2001: 25 publications 2002: 17 publications 2003: 23 publications 2004: 27 publications 2005: 38 publications 2006: 28 publications 2007: 23 publications 2008: 26 publications 2009: 30 publications 2010: 33 publications 2011: 33 publications 2012: 22 publications 2013: 26 publications 2014: 32 publications 2015: 15 publications 2016: 19 publications 2017: 28 publications 2018: 27 publications 2019: 29 publications 2020: 22 publications 2021: 28 publications 2022: 16 publications 2023: 12 publications 2024: 16 publications 2025: 27 publications 2026: 1 publication
1980 2026

824 publications in total across all disciplines

View publications per year as a table
William F. DeGrado: publications per year, 1980 to 2026
Year Publications
1980 4
1981 2
1982 3
1983 1
1984 3
1985 5
1986 4
1987 6
1988 4
1989 8
1990 8
1991 4
1992 14
1993 12
1994 21
1995 9
1996 27
1997 18
1998 15
1999 18
2000 15
2001 25
2002 17
2003 23
2004 27
2005 38
2006 28
2007 23
2008 26
2009 30
2010 33
2011 33
2012 22
2013 26
2014 32
2015 15
2016 19
2017 28
2018 27
2019 29
2020 22
2021 28
2022 16
2023 12
2024 16
2025 27
2026 1
Total 824
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William F. DeGrado publications per year - data summary

  • William F. DeGrado, a Chemistry scholar from University of California, San Francisco, has 824 publications recorded across 47 years, from 1980 to 2026.
  • The oldest publication on record dates to 1980 and the most recent to 2026.
  • The most productive year is 2005, with 38 publications.
  • The least productive years with any output are 1983 and 2026, with 1 publication each.
  • The rate of publication averages 17.5 papers per year over the whole span, or 17.5 per year counting only the 47 years with at least one publication.
  • The last 5 years on the chart (2022-2026) hold 72 publications, 9% of the career total.
  • Split into equal eras - 1980-1995: 108 publications (6.8 per year); 1996-2011: 396 publications (24.8 per year); 2012-2026: 320 publications (21.3 per year).
  • Comparing the opening and closing eras, the overall trend of publication is rising.

William F. DeGrado publication distribution in Chemistry in 2026

The chart shows the distribution of publications by all Research.com ranked scientists in the field of Chemistry in 2026. The highlighted bar marks where William F. DeGrado sits on this spectrum.

No. of scientists
250 500 750 1,000 1,250
Bar chart with 63 bars. Horizontal axis: publications, 61–80 to 1,295+. Vertical axis: number of scientists, 0 to 1,350. Most scientists, 1,350, have 161–180 publications. The last bar groups every scientist with 1,295 publications or more. The highlighted bar, 721–740 publications, is where this scientist sits. 61–80 publications: 66 scientists 81–100 publications: 302 scientists 101–120 publications: 623 scientists 121–140 publications: 918 scientists 141–160 publications: 1,218 scientists 161–180 publications: 1,350 scientists 181–200 publications: 1,344 scientists 201–220 publications: 1,281 scientists 221–240 publications: 1,216 scientists 241–260 publications: 1,100 scientists 261–280 publications: 979 scientists 281–300 publications: 939 scientists 301–320 publications: 764 scientists 321–340 publications: 643 scientists 341–360 publications: 628 scientists 361–380 publications: 522 scientists 381–400 publications: 459 scientists 401–420 publications: 397 scientists 421–440 publications: 327 scientists 441–460 publications: 270 scientists 461–480 publications: 265 scientists 481–500 publications: 252 scientists 501–520 publications: 201 scientists 521–540 publications: 185 scientists 541–560 publications: 148 scientists 561–580 publications: 148 scientists 581–600 publications: 132 scientists 601–620 publications: 114 scientists 621–640 publications: 104 scientists 641–660 publications: 91 scientists 661–680 publications: 92 scientists 681–700 publications: 73 scientists 701–720 publications: 57 scientists 721–740 publications: 54 scientists 741–760 publications: 67 scientists 761–780 publications: 45 scientists 781–800 publications: 46 scientists 801–820 publications: 39 scientists 821–840 publications: 32 scientists 841–860 publications: 36 scientists 861–880 publications: 29 scientists 881–900 publications: 26 scientists 901–920 publications: 24 scientists 921–940 publications: 14 scientists 941–960 publications: 23 scientists 961–980 publications: 28 scientists 981–1,000 publications: 15 scientists 1,001–1,020 publications: 29 scientists 1,021–1,040 publications: 12 scientists 1,041–1,060 publications: 19 scientists 1,061–1,080 publications: 12 scientists 1,081–1,100 publications: 6 scientists 1,101–1,120 publications: 8 scientists 1,121–1,140 publications: 12 scientists 1,141–1,160 publications: 5 scientists 1,161–1,180 publications: 6 scientists 1,181–1,200 publications: 14 scientists 1,201–1,220 publications: 7 scientists 1,221–1,240 publications: 2 scientists 1,241–1,260 publications: 6 scientists 1,261–1,280 publications: 4 scientists 1,281–1,294 publications: 6 scientists 1,295+ publications: 100 scientists
61–80 publications 1,295+

This scientist: 722 publications — 96th percentile

96% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 1,295 publications or more.

View publications distribution as a table
Number of Chemistry scientists by publication count, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
Publications Scientists This scientist
61–80 66
81–100 302
101–120 623
121–140 918
141–160 1,218
161–180 1,350
181–200 1,344
201–220 1,281
221–240 1,216
241–260 1,100
261–280 979
281–300 939
301–320 764
321–340 643
341–360 628
361–380 522
381–400 459
401–420 397
421–440 327
441–460 270
461–480 265
481–500 252
501–520 201
521–540 185
541–560 148
561–580 148
581–600 132
601–620 114
621–640 104
641–660 91
661–680 92
681–700 73
701–720 57
721–740 54 722
741–760 67
761–780 45
781–800 46
801–820 39
821–840 32
841–860 36
861–880 29
881–900 26
901–920 24
921–940 14
941–960 23
961–980 28
981–1,000 15
1,001–1,020 29
1,021–1,040 12
1,041–1,060 19
1,061–1,080 12
1,081–1,100 6
1,101–1,120 8
1,121–1,140 12
1,141–1,160 5
1,161–1,180 6
1,181–1,200 14
1,201–1,220 7
1,221–1,240 2
1,241–1,260 6
1,261–1,280 4
1,281–1,294 6
1,295+ 100
Download as CSV

William F. DeGrado publication distribution in Chemistry in 2026 - data summary

  • The chart plots the publication count of all 17,934 Chemistry scientists ranked by Research.com in 2026, grouped into 63 ranges running from 61–80 to 1,295+ publications.
  • William F. DeGrado, a Chemistry scholar from University of California, San Francisco, records 722 publications - the 96th percentile of the discipline.
  • 96% of ranked Chemistry scientists score the same or lower than William F. DeGrado, and about 4% score higher.
  • The median of the discipline falls in the 241–260 publications range, and William F. DeGrado ranks above the median.
  • The most crowded range is 161–180 publications, holding 1,350 scientists (8% of the field).
  • 77% of the field sits in the lowest quarter of the value range (up to 361–380 publications), so the distribution is heavily right-skewed and high scores are rare.
  • The final bar has no upper bound: it groups every scientist with 1,295 publications or more, 100 scientists in all (<1% of the field).

William F. DeGrado D-index placement in Chemistry in 2026

The chart shows the D-index (discipline H-index) distribution of Chemistry scientists ranked by Research.com in 2026. The highlighted bar marks where William F. DeGrado sits on this spectrum.

No. of scientists
250 500 750 1,000
Bar chart with 61 bars. Horizontal axis: D-Index, 40–41 to 159+. Vertical axis: number of scientists, 0 to 1,051. Most scientists, 1,051, have 56–57 D-Index. The last bar groups every scientist with 159 D-Index or more. The highlighted bar, 136–137 D-Index, is where this scientist sits. 40–41 D-Index: 289 scientists 42–43 D-Index: 612 scientists 44–45 D-Index: 808 scientists 46–47 D-Index: 776 scientists 48–49 D-Index: 835 scientists 50–51 D-Index: 861 scientists 52–53 D-Index: 872 scientists 54–55 D-Index: 933 scientists 56–57 D-Index: 1,051 scientists 58–59 D-Index: 930 scientists 60–61 D-Index: 882 scientists 62–63 D-Index: 834 scientists 64–65 D-Index: 731 scientists 66–67 D-Index: 775 scientists 68–69 D-Index: 683 scientists 70–71 D-Index: 646 scientists 72–73 D-Index: 561 scientists 74–75 D-Index: 501 scientists 76–77 D-Index: 437 scientists 78–79 D-Index: 388 scientists 80–81 D-Index: 354 scientists 82–83 D-Index: 292 scientists 84–85 D-Index: 275 scientists 86–87 D-Index: 254 scientists 88–89 D-Index: 235 scientists 90–91 D-Index: 185 scientists 92–93 D-Index: 192 scientists 94–95 D-Index: 155 scientists 96–97 D-Index: 163 scientists 98–99 D-Index: 125 scientists 100–101 D-Index: 105 scientists 102–103 D-Index: 105 scientists 104–105 D-Index: 112 scientists 106–107 D-Index: 88 scientists 108–109 D-Index: 68 scientists 110–111 D-Index: 69 scientists 112–113 D-Index: 65 scientists 114–115 D-Index: 79 scientists 116–117 D-Index: 61 scientists 118–119 D-Index: 44 scientists 120–121 D-Index: 37 scientists 122–123 D-Index: 40 scientists 124–125 D-Index: 33 scientists 126–127 D-Index: 26 scientists 128–129 D-Index: 34 scientists 130–131 D-Index: 35 scientists 132–133 D-Index: 25 scientists 134–135 D-Index: 27 scientists 136–137 D-Index: 17 scientists 138–139 D-Index: 16 scientists 140–141 D-Index: 20 scientists 142–143 D-Index: 20 scientists 144–145 D-Index: 15 scientists 146–147 D-Index: 9 scientists 148–149 D-Index: 9 scientists 150–151 D-Index: 16 scientists 152–153 D-Index: 11 scientists 154–155 D-Index: 9 scientists 156–157 D-Index: 3 scientists 158 D-Index: 3 scientists 159+ D-Index: 98 scientists
40–41 D-Index 159+

This scientist: 136 D-Index — 99th percentile

99% of scientists in this discipline score the same or lower.

The last bar groups every scientist with 159 D-Index or more.

View D-Index distribution as a table
Number of Chemistry scientists by D-index, Research.com 2026 ranking edition. Based on 17,934 ranked scientists.
D-Index Scientists This scientist
40–41 289
42–43 612
44–45 808
46–47 776
48–49 835
50–51 861
52–53 872
54–55 933
56–57 1,051
58–59 930
60–61 882
62–63 834
64–65 731
66–67 775
68–69 683
70–71 646
72–73 561
74–75 501
76–77 437
78–79 388
80–81 354
82–83 292
84–85 275
86–87 254
88–89 235
90–91 185
92–93 192
94–95 155
96–97 163
98–99 125
100–101 105
102–103 105
104–105 112
106–107 88
108–109 68
110–111 69
112–113 65
114–115 79
116–117 61
118–119 44
120–121 37
122–123 40
124–125 33
126–127 26
128–129 34
130–131 35
132–133 25
134–135 27
136–137 17 136
138–139 16
140–141 20
142–143 20
144–145 15
146–147 9
148–149 9
150–151 16
152–153 11
154–155 9
156–157 3
158 3
159+ 98
Download as CSV

William F. DeGrado D-index placement in Chemistry in 2026 - data summary

  • The chart plots the discipline H-index (D-index) of all 17,934 Chemistry scientists ranked by Research.com in 2026, grouped into 61 ranges running from 40–41 to 159+ D-Index.
  • William F. DeGrado, a Chemistry scholar from University of California, San Francisco, records 136 D-Index - the 99th percentile of the discipline.
  • 99% of ranked Chemistry scientists score the same or lower than William F. DeGrado, and about 1% score higher.
  • The median of the discipline falls in the 62–63 D-Index range, and William F. DeGrado ranks above the median.
  • The most crowded range is 56–57 D-Index, holding 1,051 scientists (6% of the field).
  • 70% of the field sits in the lowest quarter of the value range (up to 70–71 D-Index), so the distribution is heavily right-skewed and high scores are rare.
  • The final bar has no upper bound: it groups every scientist with 159 D-Index or more, 98 scientists in all (<1% of the field).

Research.com Recognitions

  • 2026 - Research.com Chemistry in United States Leader Award
  • 2025 - Research.com Chemistry in United States Leader Award
  • 2017 - Murray Goodman Memorial Prize, American Chemical Society (ACS)
  • 2013 - Fellow, National Academy of Inventors
  • 1999 - Member of the National Academy of Sciences
  • 1998 - Fellow of the American Academy of Arts and Sciences
  • 1994 - Fellow of the American Association for the Advancement of Science (AAAS)

Overview

William F. DeGrado is affiliated with the University of California, San Francisco in the United States. Their research primarily spans the fields of Biochemistry, Genetics and Molecular Biology, and Medicine. Within these domains, their work notably focuses on Molecular Biology, Materials Chemistry, Neurology, Physiology, and Organic Chemistry.

The main topics addressed in DeGrado's research include:

  • Protein Structure and Dynamics
  • RNA and protein synthesis mechanisms
  • Alzheimer's disease research and treatments
  • Chemical Synthesis and Analysis
  • Enzyme Structure and Function
  • Lipid Membrane Structure and Behavior
  • Monoclonal and Polyclonal Antibodies Research

Several recent publications exemplify the scope of their work, including:

  • De novo protein design, a retrospective (2020) in Quarterly Reviews of Biophysics
  • A defined structural unit enables de novo design of small-molecule-binding proteins (2020) in Science
  • Constructing ion channels from water-soluble α-helical barrels (2021) in Nature Chemistry
  • De novo metalloprotein design (2021) in Nature Reviews Chemistry
  • Deep mutational scanning reveals the structural basis for α-synuclein activity (2020) in Nature Chemical Biology

DeGrado has collaborated frequently with several coauthors, most notably:

  • Hyunil Jo
  • Sophia K. Tan
  • Nicholas F. Polizzi
  • Carlo Condello
  • Huong T. Kratochvil

Their research findings have been published extensively in venues including:

  • bioRxiv (Cold Spring Harbor Laboratory)
  • Journal of the American Chemical Society
  • Proceedings of the National Academy of Sciences
  • Biophysical Journal
  • Biochemistry

Throughout their career, William F. DeGrado has received several recognitions:

  • Murray Goodman Memorial Prize, American Chemical Society (ACS), 2017
  • Fellow, National Academy of Inventors, 2013
  • Member of the National Academy of Sciences, 1999
  • Fellow of the American Academy of Arts and Sciences, 1998
  • Fellow of the American Association for the Advancement of Science (AAAS), 1994

Best Publications

  • beta-Peptides: from structure to function.

    Richard P. Cheng;Samuel H. Gellman;William F. DeGrado

  • A thermodynamic scale for the helix-forming tendencies of the commonly occurring amino acids

    Karyn T. O'Neil;William F. Degrado

  • How calmodulin binds its targets: sequence independent recognition of amphiphilic α-helices

    Karyn T. O'Neil;William F. DeGrado

  • Foldamers as versatile frameworks for the design and evolution of function

    Catherine M Goodman;Sungwook Choi;Sungwook Choi;Scott Shandler;William F DeGrado

  • Characterization of a helical protein designed from first principles

    Lynne Regan;William F. DeGrado

  • De Novo Design and Structural Characterization of Proteins and Metalloproteins

    William F. DeGrado;Christopher M. Summa;Vincenzo Pavone;Flavia Nastri

  • Synthetic amphiphilic peptide models for protein ion channels

    JD Lear;ZR Wasserman;WF DeGrado

  • Protein Design: A Hierarchic Approach

    James W. Bryson;Stephen F. Betz;Helen S. Lu;Daniel J. Suich

  • Structure of the amantadine binding site of influenza M2 proton channels in lipid bilayers

    Sarah D. Cady;Klaus Schmidt-Rohr;Jun Wang;Cinque S. Soto

  • Structural basis for the function and inhibition of an influenza virus proton channel

    Amanda L. Stouffer;Amanda L. Stouffer;Rudresh Acharya;David Salom;Anna S. Levine

  • Protein design, a minimalist approach

    William F. DeGrado;Zelda R. Wasserman;James D. Lear

  • Short peptides self-assemble to produce catalytic amyloids

    Caroline M. Rufo;Yurii S. Moroz;Olesia V. Moroz;Jan Stöhr

  • De Novo Design of Antimicrobial Polymers, Foldamers, and Small Molecules: From Discovery to Practical Applications

    Gregory N. Tew;Richard W. Scott;Michael L. Klein;William F. DeGrado

  • Design and synthesis of multi-haem proteins

    D E Robertson;R S Farid;C C Moser;J L Urbauer

  • De novo design of biomimetic antimicrobial polymers

    Gregory N. Tew;Dahui Liu;Bin Chen;Robert J. Doerksen

  • Amphiphilic polymethacrylate derivatives as antimicrobial agents.

    Kenichi Kuroda;William F. DeGrado

  • Folding of helical membrane proteins: the role of polar, GxxxG-like and proline motifs.

    Alessandro Senes;Donald E Engel;William F DeGrado

  • A functionally defined model for the M2 proton channel of influenza A virus suggests a mechanism for its ion selectivity.

    Lawrence H. Pinto;Gregg R. Dieckmann;Chris S. Gandhi;Carol G. Papworth

  • Induction of peptide conformation at apolar water interfaces. 1. A study with model peptides of defined hydrophobic periodicity

    W. F. DeGrado;J. D. Lear

  • De Novo Design of Antibacterial β-Peptides

    Yoshi Hamuro;and Joel P. Schneider;William F. DeGrado

Frequent Co-Authors

James D. Lear
James D. Lear University of Pennsylvania
Joel S. Bennett
Joel S. Bennett University of Pennsylvania
Feng Gai
Feng Gai University of Pennsylvania
Michael L. Klein
Michael L. Klein Temple University
Angela Lombardi
Angela Lombardi University of Naples Federico II
Robert A. Lamb
Robert A. Lamb Northwestern University
Lawrence H. Pinto
Lawrence H. Pinto Northwestern University
Mei Hong
Mei Hong MIT
Gregory N. Tew
Gregory N. Tew University of Massachusetts Amherst
Vincenzo Pavone
Vincenzo Pavone University of Naples Federico II

External Links

Wikipedia of William F. DeGrado Personal website of William F. DeGrado

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