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Charles M. Deber

Charles M. Deber

D-Index & Metrics

Chemistry

D-Index
69
Citations
14700
World Ranking
6308
National Ranking
166

Biology and Biochemistry

D-Index
69
Citations
14662
World Ranking
7517
National Ranking
260

Research.com Recognitions

  • 2001 - Fellow of the Royal Society of Canada Academy of Science

Overview

Charles M. Deber is affiliated with the University of Toronto in Canada. Their research is primarily situated within the fields of Biochemistry, Genetics and Molecular Biology, as well as Immunology and Microbiology.

The scientist's research work spans several subfields, including Molecular Biology, Microbiology, Molecular Medicine, Pulmonary and Respiratory Medicine, and Immunology. Key topics explored in their publications include Antimicrobial Peptides and Activities, Antibiotic Resistance in Bacteria, Cystic Fibrosis Research Advances, Lipid Membrane Structure and Behavior, Biochemical and Structural Characterization, ATP Synthase and ATPases Research, and Mitochondrial Function and Pathology.

Frequent co-authors collaborating with Charles M. Deber are Tyler S. Johnson, Chloe J Mitchell, Shelley He, Tracy A. Stone, and Michael Schlierf.

The scientist has published multiple papers across several venues. Frequent publication venues include Biophysical Journal, Biochemistry, International Journal of Molecular Sciences, Journal of Cystic Fibrosis, and Scientific Reports.

Recent papers authored in collaboration are the following:

  • Anti-Infectives Restore ORKAMBI® Rescue of F508del-CFTR Function in Human Bronchial Epithelial Cells Infected with Clinical Strains of P. aeruginosa, 2020, Biomolecules
  • Interaction of designed cationic antimicrobial peptides with the outer membrane of gram-negative bacteria, 2024, Scientific Reports
  • Uncoupling Amphipathicity and Hydrophobicity: Role of Charge Clustering in Membrane Interactions of Cationic Antimicrobial Peptides, 2021, Biochemistry
  • Enhanced proteolytic resistance of cationic antimicrobial peptides through lysine side chain analogs and cyclization, 2022, Biochemical and Biophysical Research Communications
  • Peptide-Based Approach to Inhibition of the Multidrug Resistance Efflux Pump AcrB, 2020, Biochemistry

Charles M. Deber was awarded the title of Fellow of the Royal Society of Canada in 2001 by the Academy of Science.

Best Publications

  • Detergent binding explains anomalous SDS-PAGE migration of membrane proteins

    Arianna Rath;Mira Glibowicka;Vincent G. Nadeau;Gong Chen

  • Roles of Hydrophobicity and Charge Distribution of Cationic Antimicrobial Peptides in Peptide-Membrane Interactions

    Lois M. Yin;Michelle A. Edwards;Jessica Li;Christopher M. Yip

  • Non-random distribution of amino acids in the transmembrane segments of human type I single span membrane proteins.

    Carolina Landolt-Marticorena;Karen A. Williams;Charles M. Deber;Reinhart A.F. Reithmeier

  • Hypothesis about the function of membrane-buried proline residues in transport proteins.

    Christopher J. Brandl;Charles M. Deber

  • Alpha-helical, but not beta-sheet, propensity of proline is determined by peptide environment

    Shun-Cheng Li;Natalie K. Goto;Karen A. Williams;Charles M. Deber

  • Basis for Selectivity of Cationic Antimicrobial Peptides for Bacterial Versus Mammalian Membranes

    Evgenia Glukhov;Margareta Stark;Lori L. Burrows;Charles M. Deber

  • Proline residues in transmembrane helices : structural or dynamic role ?

    Karen A. Williams;Charles M. Deber

  • Why cyclic peptides? Complementary approaches to conformations

    Charles M. Deber;Vincent Madison;Elkan R. Blout

  • Cationic Hydrophobic Peptides with Antimicrobial Activity

    Margareta Stark;Li-Ping Liu;Charles M. Deber

  • Conformations of (X-L-Pro-Y)2 cyclic hexapeptides. Preferred beta-turn conformers and implications for beta turns in proteins.

    Lila M. Gierasch;Charles M. Deber;Vincent Madison;Chien-Hua Niu

  • Nuclear magnetic resonance evidence for cis-peptide bonds in proline oligomers.

    C. M. Deber;F. A. Bovey;J. P. Carver;Elkan R. Blout

  • The structure of “unstructured” regions in peptides and proteins: Role of the polyproline II helix in protein folding and recognition

    Arianna Rath;Alan R. Davidson;Charles M. Deber

  • A measure of helical propensity for amino acids in membrane environments.

    Shun-Cheng Li;Charles M. Deber

  • TM Finder: a prediction program for transmembrane protein segments using a combination of hydrophobicity and nonpolar phase helicity scales.

    C M Deber;C Wang;L P Liu;A S Prior

  • SDS Micelles as a Membrane-Mimetic Environment for Transmembrane Segments

    David V. Tulumello;Charles M. Deber

  • Central nervous system myelin: structure, function, and pathology.

    Charles M. Deber;Steven J. Reynolds

  • Guidelines for membrane protein engineering derived from de novo designed model peptides.

    Li-Ping Liu;Charles M. Deber

  • Cyclic peptides. IX. Conformations of a synthetic ion-binding cyclic peptide, cyclo-(Pro-Gly)3, from circular dichroism and proton and carbon-13 nuclear magnetic resonance

    V. Madison;M. Atreyi;C. M. Deber;E. R. Blout

  • Missense mutations in transmembrane domains of proteins: Phenotypic propensity of polar residues for human disease

    Anthony W. Partridge;Alex G. Therien;Charles M. Deber

  • Transmembrane aromatic amino acid distribution in P-glycoprotein. A functional role in broad substrate specificity

    Asha B. Pawagi;Jing Wang;Melvin Silverman;Reinhart A.F. Reithmeier

  • The affinity of GXXXG motifs in transmembrane helix-helix interactions is modulated by long-range communication.

    Roman A. Melnyk;Sanguk Kim;A. Rachael Curran;Donald M. Engelman

  • A measure of helical propensity for amino acids in membrane environments

    Unknown

Frequent Co-Authors

Elkan R. Blout
Elkan R. Blout Harvard University
Mario A. Moscarello
Mario A. Moscarello University of Toronto
Lori L. Burrows
Lori L. Burrows McMaster University
Christine E. Bear
Christine E. Bear University of Toronto
G. Andrew Woolley
G. Andrew Woolley University of Toronto
Paul E. Fraser
Paul E. Fraser University of Toronto
Lila M. Gierasch
Lila M. Gierasch University of Massachusetts Amherst
Gunnar von Heijne
Gunnar von Heijne Stockholm University
Raisa B. Deber
Raisa B. Deber University of Toronto
Joan M. Boggs
Joan M. Boggs University of Toronto

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