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Chemistry

D-Index
65
Citations
13477
World Ranking
7755
National Ranking
2264

Overview

Roger E. Koeppe is affiliated with the University of Arkansas at Fayetteville in the United States. Their research primarily focuses on the fields of biochemistry, genetics, and molecular biology, with specific expertise in molecular biology, atomic and molecular physics and optics, biomaterials, spectroscopy, and biomedical engineering.

The scientist's work extensively covers topics such as lipid membrane structure and behavior, protein structure and dynamics, RNA and protein synthesis mechanisms, spectroscopy and quantum chemical studies, supramolecular self-assembly in materials, advanced NMR techniques and applications, and force microscopy techniques and applications.

Frequent co-authors collaborating with Roger E. Koeppe include Denise V. Greathouse, Matthew J. McKay, Fahmida Afrose, Jake R. Price, and Kelsey Anne Marr.

Their scholarly output appears predominantly in a few key publication venues, including Biophysical Journal, ACS Omega, International Journal of Molecular Sciences, FEBS Letters, and Faraday Discussions.

Recent published papers reflect ongoing interest in membrane biophysics and peptide dynamics. Notable publications include:

  • Intrinsic Lipid Curvature and Bilayer Elasticity as Regulators of Channel Function: A Comparative Single-Molecule Study, 2024, International Journal of Molecular Sciences
  • Flanking aromatic residue competition influences transmembrane peptide helix dynamics, 2020, FEBS Letters
  • Membrane electrostatics sensed by tryptophan anchors in hydrophobic model peptides depends on non-aromatic interfacial amino acids: implications in hydrophobic mismatch, 2020, Faraday Discussions
  • Examination of pH dependency and orientation differences of membrane spanning alpha helices carrying a single or pair of buried histidine residues, 2020, Biochimica et Biophysica Acta (BBA) - Biomembranes
  • Lipid-Dependent Titration of Glutamic Acid at a Bilayer Membrane Interface, 2021, ACS Omega

Best Publications

  • Bilayer Thickness and Membrane Protein Function: An Energetic Perspective

    Olaf S. Andersen;Roger E. Koeppe

  • Different Membrane Anchoring Positions of Tryptophan and Lysine in Synthetic Transmembrane α-Helical Peptides

    Maurits R.R. de Planque;John A.W. Kruijtzer;Rob M.J. Liskamp;Derek Marsh

  • Induction of nonbilayer structures in diacylphosphatidylcholine model membranes by transmembrane alpha-helical peptides: importance of hydrophobic mismatch and proposed role of tryptophans.

    J. A. Killian;I. Salemink;M. R. R. De Planque;G. Lindblom

  • Bilayer-dependent inhibition of mechanosensitive channels by neuroactive peptide enantiomers.

    Thomas M. Suchyna;Sonya E. Tape;Roger E. Koeppe;Olaf S. Andersen

  • Influence of lipid/peptide hydrophobic mismatch on the thickness of diacylphosphatidylcholine bilayers. A 2H NMR and ESR study using designed transmembrane alpha-helical peptides and gramicidin A.

    M. R. R. De Planque;D. V. Greathouse;R. E. Koeppe;H. Schafer

  • Interfacial Anchor Properties of Tryptophan Residues in Transmembrane Peptides Can Dominate over Hydrophobic Matching Effects in Peptide−Lipid Interactions†

    M.R.R. de Planque;B.B. Bonev;J.A.A. Demmers;D.V. Greathouse

  • Regulation of sodium channel function by bilayer elasticity: the importance of hydrophobic coupling. Effects of Micelle-forming amphiphiles and cholesterol.

    Jens A. Lundbaek;Jens A. Lundbaek;P. I. A. Birn;Anker J. Hansen;Rikke Søgaard

  • Molecular determinants of channel function

    O. S. Andersen;R. E. Koeppe

  • Kinetics of gramicidin channel formation in lipid bilayers: transmembrane monomer association.

    Anne M. O'Connell;Roger E. Koeppe;Olaf S. Andersen

  • Capsaicin Regulates Voltage-Dependent Sodium Channels by Altering Lipid Bilayer Elasticity

    Jens Lundbaek;P. Birn;S. E. Tape;Gilman E. S. Toombes

  • Precursors in vivo of glutamate, aspartate and their derivatives of rat brain.

    R. M. O'Neal;R. E. Koeppe

  • Sensitivity of single membrane-spanning alpha-helical peptides to hydrophobic mismatch with a lipid bilayer: effects on backbone structure, orientation, and extent of membrane incorporation.

    M.R.R. de Planque;E. Goormaghtigh;D.V. Greathouse;R.E. Koeppe Ii

  • Geometry and Intrinsic Tilt of a Tryptophan-Anchored Transmembrane α-Helix Determined by 2H NMR

    Patrick C.A. van der Wel;Erik Strandberg;J. Antoinette Killian;Roger E. Koeppe

  • Tilt Angles of Transmembrane Model Peptides in Oriented and Non-Oriented Lipid Bilayers as Determined by 2H Solid-State NMR

    Erik Strandberg;Suat Özdirekcan;Dirk T.S. Rijkers;Patrick C.A. van der Wel

  • Engineering the gramicidin channel.

    Unknown

  • Amino acid sequence modulation of gramicidin channel function: effects of tryptophan-to-phenylalanine substitutions on the single-channel conductance and duration.

    Murray D. Becker;Denise V. Greathouse;Roger E. Koeppe;Olaf S. Andersen

  • Docosahexaenoic acid alters bilayer elastic properties

    Michael J. Bruno;Roger E. Koeppe;Olaf S. Andersen

  • Hydrophobic mismatch between helices and lipid bilayers.

    Thomas M. Weiss;Patrick C.A. van der Wel;J. Antoinette Killian;Roger E. Koeppe

  • Genistein can modulate channel function by a phosphorylation-independent mechanism: importance of hydrophobic mismatch and bilayer mechanics.

    Tzyh Chang Hwang;Roger E. Koeppe;Olaf S. Andersen

  • Curcumin is a Modulator of Bilayer Material Properties

    Helgi I Ingolfsson;Roger E Koeppe;Olaf S Andersen

  • Gramicidin channels

    O.S. Andersen;R.E. Koeppe;B. Roux

Frequent Co-Authors

Olaf S. Andersen
Olaf S. Andersen Cornell University
J. Antoinette Killian
J. Antoinette Killian Utrecht University
Stanley J. Opella
Stanley J. Opella University of California, San Diego
Benoît Roux
Benoît Roux University of Chicago
Amitabha Chattopadhyay
Amitabha Chattopadhyay Centre for Cellular and Molecular Biology
Robert M. Stroud
Robert M. Stroud University of California, San Francisco
John Katsaras
John Katsaras Oak Ridge National Laboratory
Göran Lindblom
Göran Lindblom Umeå University
Mark S.P. Sansom
Mark S.P. Sansom University of Oxford

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