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J. Antoinette Killian

J. Antoinette Killian

D-Index & Metrics

Chemistry

D-Index
72
Citations
16806
World Ranking
5326
National Ranking
127

Overview

J. Antoinette Killian is affiliated with Utrecht University in the Netherlands. Their research primarily focuses on the biochemical and molecular biological aspects of lipid membranes and related areas of cellular function and disease mechanisms.

The scientist has contributed to various fields, with main research areas covering:

  • Biochemistry, Genetics and Molecular Biology
  • Medicine

Within these broader domains, subfields of study include:

  • Molecular Biology
  • Cell Biology
  • Surgery
  • Physiology
  • Organic Chemistry

Killian's work addresses multiple key topics such as:

  • Lipid Membrane Structure and Behavior
  • Pancreatic Function and Diabetes
  • Alzheimer's Disease Research and Treatments
  • Endoplasmic Reticulum Stress and Disease
  • Hemoglobin Structure and Function
  • Molecular Sensors and Ion Detection
  • Plasma Applications and Diagnostics

Recent papers authored or co-authored by Killian reflect a range of biochemical and biophysical studies related to membrane proteins and polymers, including:

  • Mass Photometry of Membrane Proteins, 2020, Chem
  • Iterative RAFT-Mediated Copolymerization of Styrene and Maleic Anhydride toward Sequence- and Length-Controlled Copolymers and Their Applications for Solubilizing Lipid Membranes, 2020, Biomacromolecules
  • Synthesis and Evaluation of a Library of Alternating Amphipathic Copolymers to Solubilize and Study Membrane Proteins, 2022, Biomacromolecules
  • Membrane-Catalyzed Aggregation of Islet Amyloid Polypeptide Is Dominated by Secondary Nucleation, 2022, Biochemistry
  • A Broad-Spectrum Antiviral Peptide Blocks Infection of Viruses by Binding to Phosphatidylserine in the Viral Envelope, 2020, Cells

The scientist's frequent co-authors include the following researchers, indicating collaborative efforts in related research topics:

  • Barend O. W. Elenbaas
  • Adrian H. Kopf
  • Cornelis A. van Walree
  • Joseph H. Lorent
  • Lucie Khemtémourian

Publication venues frequently featuring Killian's work include:

  • Biophysical Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • Biomacromolecules
  • Chem
  • Biochemistry

Best Publications

  • How proteins adapt to a membrane-water interface.

    J.Antoinette Killian;Gunnar von Heijne

  • Hydrophobic mismatch between proteins and lipids in membranes

    J.Antoinette Killian

  • Nonbilayer lipids affect peripheral and integral membrane proteins via changes in the lateral pressure profile.

    Els van den Brink-van der Laan;J. Antoinette Killian;Ben de Kruijff

  • Membrane damage by human islet amyloid polypeptide through fibril growth at the membrane.

    Maarten F. M. Engel;Lucie Khemtémourian;Cécile C. Kleijer;Hans J. D. Meeldijk

  • The styrene-maleic acid copolymer: a versatile tool in membrane research

    Jonas M. Dörr;Stefan Scheidelaar;Martijn C. Koorengevel;Juan J. Dominguez

  • Different Membrane Anchoring Positions of Tryptophan and Lysine in Synthetic Transmembrane α-Helical Peptides

    Maurits R.R. de Planque;John A.W. Kruijtzer;Rob M.J. Liskamp;Derek Marsh

  • Protein–lipid interactions studied with designed transmembrane peptides: role of hydrophobic matching and interfacial anchoring (Review)

    Maurits R R de Planque;J Antoinette Killian

  • Lateral diffusion of membrane proteins.

    Sivaramakrishnan Ramadurai;Andrea Holt;Victor Krasnikov;Geert van den Bogaart

  • Detergent-free isolation, characterization, and functional reconstitution of a tetrameric K+ channel: the power of native nanodiscs.

    Jonas M. Dörr;Martijn C. Koorengevel;Marre Schäfer;Alexander V. Prokofyev

  • Influence of lipid/peptide hydrophobic mismatch on the thickness of diacylphosphatidylcholine bilayers. A 2H NMR and ESR study using designed transmembrane alpha-helical peptides and gramicidin A.

    M. R. R. De Planque;D. V. Greathouse;R. E. Koeppe;H. Schafer

  • Interfacial Anchor Properties of Tryptophan Residues in Transmembrane Peptides Can Dominate over Hydrophobic Matching Effects in Peptide−Lipid Interactions†

    M.R.R. de Planque;B.B. Bonev;J.A.A. Demmers;D.V. Greathouse

  • Islet amyloid polypeptide-induced membrane leakage involves uptake of lipids by forming amyloid fibers.

    Emma Sparr;Maarten F.M. Engel;Dmitri V. Sakharov;Mariette Sprong

  • Gramicidin and gramicidin-lipid interactions.

    J. Antoinette Killian

  • Snorkeling of lysine side chains in transmembrane helices: how easy can it get?

    Erik Strandberg;J.Antoinette Killian

  • Lipid packing drives the segregation of transmembrane helices into disordered lipid domains in model membranes

    Lars V. Schäfer;Djurre H. de Jong;Andrea Holt;Andrzej J. Rzepiela

  • Sensitivity of single membrane-spanning alpha-helical peptides to hydrophobic mismatch with a lipid bilayer: effects on backbone structure, orientation, and extent of membrane incorporation.

    M.R.R. de Planque;E. Goormaghtigh;D.V. Greathouse;R.E. Koeppe Ii

  • Geometry and Intrinsic Tilt of a Tryptophan-Anchored Transmembrane α-Helix Determined by 2H NMR

    Patrick C.A. van der Wel;Erik Strandberg;J. Antoinette Killian;Roger E. Koeppe

  • Molecular model for the solubilization of membranes into nanodisks by styrene maleic Acid copolymers.

    Stefan Scheidelaar;Martijn C. Koorengevel;Juan Dominguez Pardo;Johannes D. Meeldijk

  • Polymorphic regulation of membrane phospholipid composition in Escherichia coli.

    A G Rietveld;J A Killian;W Dowhan;B de Kruijff

  • Tilt Angles of Transmembrane Model Peptides in Oriented and Non-Oriented Lipid Bilayers as Determined by 2H Solid-State NMR

    Erik Strandberg;Suat Özdirekcan;Dirk T.S. Rijkers;Patrick C.A. van der Wel

  • RNA molecules that specifically and stoichiometrically bind aminoglycoside antibiotics with high affinities.

    Yong Wang;Jennifer Killian;Keita Hamasaki;Robert R. Rando

  • Synthetic peptides as models for intrinsic membrane proteins

    J.Antoinette Killian

Frequent Co-Authors

Dirk T. S. Rijkers
Dirk T. S. Rijkers Utrecht University
Roger E. Koeppe
Roger E. Koeppe University of Arkansas at Fayetteville
Rob M. J. Liskamp
Rob M. J. Liskamp University of Glasgow
Eefjan Breukink
Eefjan Breukink Utrecht University
Armin Giese
Armin Giese Ludwig-Maximilians-Universität München
Christian Griesinger
Christian Griesinger Max Planck Society
Rienk van Grondelle
Rienk van Grondelle Vrije Universiteit Amsterdam
Andreas Kuhn
Andreas Kuhn University of Hohenheim
Diego de Mendoza
Diego de Mendoza National University of Rosario

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