2022 - Research.com Biology and Biochemistry in Israel Leader Award
Yechiel Shai mostly deals with Biochemistry, Peptide, Membrane, Antimicrobial peptides and Phospholipid. His work on Bacteria expands to the thematically related Biochemistry. The concepts of his Peptide study are interwoven with issues in Antibacterial activity, Stereochemistry, Cell membrane and Phosphatidylcholine.
His studies in Membrane integrate themes in fields like Crystallography and Biophysics. His research integrates issues of Innate immune system, Lysis, Lipopeptide and Protein secondary structure in his study of Antimicrobial peptides. His Phospholipid research includes themes of Gel electrophoresis and Wild type, Mutant.
Yechiel Shai mainly focuses on Biochemistry, Peptide, Membrane, Antimicrobial peptides and Biophysics. His study in Biochemistry concentrates on Lipid bilayer fusion, Amino acid, Peptide sequence, Mode of action and Transmembrane domain. Yechiel Shai works mostly in the field of Peptide, limiting it down to topics relating to Vesicle and, in certain cases, Pardaxin and Liposome, as a part of the same area of interest.
His work deals with themes such as Crystallography and Circular dichroism, which intersect with Membrane. The various areas that he examines in his Antimicrobial peptides study include Innate immune system and Antibiotics. His Biophysics study incorporates themes from Lipid bilayer, Ectodomain and Phosphatidylcholine.
His main research concerns Cell biology, Biochemistry, Peptide, Antimicrobial peptides and Lipid bilayer fusion. His Cell biology research incorporates elements of Cell, T cell, Immune system and Receptor, Transmembrane domain. He interconnects Lipopeptide and In vivo in the investigation of issues within Biochemistry.
His biological study spans a wide range of topics, including Biophysics, Membrane, Electron paramagnetic resonance spectroscopy and Transmission electron microscopy. In his study, Phosphatidylcholine is strongly linked to Crystallography, which falls under the umbrella field of Membrane. The study incorporates disciplines such as Antibiotic resistance and Biofilm in addition to Antimicrobial peptides.
Yechiel Shai focuses on Biochemistry, Peptide, Antimicrobial peptides, Microbiology and Innate immune system. In his study, Yechiel Shai carries out multidisciplinary Biochemistry and Enfuvirtide research. His Peptide research is multidisciplinary, incorporating perspectives in Aspergillus fumigatus, Biophysics, Membrane and In vivo.
His Membrane research is multidisciplinary, relying on both Transmission electron microscopy and Electron paramagnetic resonance spectroscopy. His work carried out in the field of Antimicrobial peptides brings together such families of science as Pseudomonas aeruginosa, Antibiotics, Antibiotic resistance and Biofilm. His study looks at the relationship between Microbiology and topics such as Bacteria, which overlap with Mutant, Cell wall and Cell aging.
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Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by α-helical antimicrobial and cell non-selective membrane-lytic peptides
Biochimica et Biophysica Acta (1999)
Mode of action of membrane active antimicrobial peptides.
Mode of action of linear amphipathic α-helical antimicrobial peptides
Ziv Oren;Yechiel Shai.
Interaction of antimicrobial dermaseptin and its fluorescently labeled analogues with phospholipid membranes.
Yehonathan Pouny;Doron Rapaport;Amram Mor;Pierre Nicolas.
Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity.
Ziv Oren;Jeffrey C. Lerman;Gudmundur H. Gudmundsson;Birgitta Agerberth.
Biochemical Journal (1999)
Host defense peptides as new weapons in cancer treatment.
N Papo;Y Shai.
Cellular and Molecular Life Sciences (2005)
Ultrashort antibacterial and antifungal lipopeptides
Arik Makovitzki;Dorit Avrahami;Yechiel Shai.
Proceedings of the National Academy of Sciences of the United States of America (2006)
Selective lysis of bacteria but not mammalian cells by diastereomers of melittin: structure-function study
Ziv Oren;Yechiel Shai.
Endotoxin (Lipopolysaccharide) Neutralization by Innate Immunity Host-Defense Peptides PEPTIDE PROPERTIES AND PLAUSIBLE MODES OF ACTION
Yosef Rosenfeld;Niv Papo;Yechiel Shai.
Journal of Biological Chemistry (2006)
Interaction of the mammalian antibacterial peptide cecropin P1 with phospholipid vesicles.
Ehud Gazit;Anita Boman;Hans G. Boman;Yechiel Shai.
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