D-Index & Metrics Best Publications
Biology and Biochemistry
Israel
2022

D-Index & Metrics D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines.

Discipline name D-index D-index (Discipline H-index) only includes papers and citation values for an examined discipline in contrast to General H-index which accounts for publications across all disciplines. Citations Publications World Ranking National Ranking
Biology and Biochemistry D-index 93 Citations 29,625 302 World Ranking 1369 National Ranking 13

Research.com Recognitions

Awards & Achievements

2022 - Research.com Biology and Biochemistry in Israel Leader Award

Overview

What is he best known for?

The fields of study he is best known for:

  • Gene
  • Biochemistry
  • Amino acid

Yechiel Shai mostly deals with Biochemistry, Peptide, Membrane, Antimicrobial peptides and Phospholipid. His work on Bacteria expands to the thematically related Biochemistry. The concepts of his Peptide study are interwoven with issues in Antibacterial activity, Stereochemistry, Cell membrane and Phosphatidylcholine.

His studies in Membrane integrate themes in fields like Crystallography and Biophysics. His research integrates issues of Innate immune system, Lysis, Lipopeptide and Protein secondary structure in his study of Antimicrobial peptides. His Phospholipid research includes themes of Gel electrophoresis and Wild type, Mutant.

His most cited work include:

  • Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by α-helical antimicrobial and cell non-selective membrane-lytic peptides (1483 citations)
  • Mode of action of membrane active antimicrobial peptides. (1145 citations)
  • Mode of action of linear amphipathic α-helical antimicrobial peptides (683 citations)

What are the main themes of his work throughout his whole career to date?

Yechiel Shai mainly focuses on Biochemistry, Peptide, Membrane, Antimicrobial peptides and Biophysics. His study in Biochemistry concentrates on Lipid bilayer fusion, Amino acid, Peptide sequence, Mode of action and Transmembrane domain. Yechiel Shai works mostly in the field of Peptide, limiting it down to topics relating to Vesicle and, in certain cases, Pardaxin and Liposome, as a part of the same area of interest.

His work deals with themes such as Crystallography and Circular dichroism, which intersect with Membrane. The various areas that he examines in his Antimicrobial peptides study include Innate immune system and Antibiotics. His Biophysics study incorporates themes from Lipid bilayer, Ectodomain and Phosphatidylcholine.

He most often published in these fields:

  • Biochemistry (47.30%)
  • Peptide (43.49%)
  • Membrane (29.84%)

What were the highlights of his more recent work (between 2011-2021)?

  • Cell biology (15.87%)
  • Biochemistry (47.30%)
  • Peptide (43.49%)

In recent papers he was focusing on the following fields of study:

His main research concerns Cell biology, Biochemistry, Peptide, Antimicrobial peptides and Lipid bilayer fusion. His Cell biology research incorporates elements of Cell, T cell, Immune system and Receptor, Transmembrane domain. He interconnects Lipopeptide and In vivo in the investigation of issues within Biochemistry.

His biological study spans a wide range of topics, including Biophysics, Membrane, Electron paramagnetic resonance spectroscopy and Transmission electron microscopy. In his study, Phosphatidylcholine is strongly linked to Crystallography, which falls under the umbrella field of Membrane. The study incorporates disciplines such as Antibiotic resistance and Biofilm in addition to Antimicrobial peptides.

Between 2011 and 2021, his most popular works were:

  • D-Alanylation of Lipoteichoic Acids Confers Resistance to Cationic Peptides in Group B Streptococcus by Increasing the Cell Wall Density (103 citations)
  • Transmembrane domains interactions within the membrane milieu: Principles, advances and challenges ☆ (92 citations)
  • Mechanisms of biofilm inhibition and degradation by antimicrobial peptides. (68 citations)

In his most recent research, the most cited papers focused on:

  • Gene
  • Amino acid
  • DNA

Yechiel Shai focuses on Biochemistry, Peptide, Antimicrobial peptides, Microbiology and Innate immune system. In his study, Yechiel Shai carries out multidisciplinary Biochemistry and Enfuvirtide research. His Peptide research is multidisciplinary, incorporating perspectives in Aspergillus fumigatus, Biophysics, Membrane and In vivo.

His Membrane research is multidisciplinary, relying on both Transmission electron microscopy and Electron paramagnetic resonance spectroscopy. His work carried out in the field of Antimicrobial peptides brings together such families of science as Pseudomonas aeruginosa, Antibiotics, Antibiotic resistance and Biofilm. His study looks at the relationship between Microbiology and topics such as Bacteria, which overlap with Mutant, Cell wall and Cell aging.

This overview was generated by a machine learning system which analysed the scientist’s body of work. If you have any feedback, you can contact us here.

Best Publications

Mechanism of the binding, insertion and destabilization of phospholipid bilayer membranes by α-helical antimicrobial and cell non-selective membrane-lytic peptides

Yechiel Shai.
Biochimica et Biophysica Acta (1999)

2353 Citations

Mode of action of membrane active antimicrobial peptides.

Yechiel Shai.
Biopolymers (2002)

1816 Citations

Mode of action of linear amphipathic α-helical antimicrobial peptides

Ziv Oren;Yechiel Shai.
Biopolymers (1998)

1063 Citations

Interaction of antimicrobial dermaseptin and its fluorescently labeled analogues with phospholipid membranes.

Yehonathan Pouny;Doron Rapaport;Amram Mor;Pierre Nicolas.
Biochemistry (1992)

790 Citations

Structure and organization of the human antimicrobial peptide LL-37 in phospholipid membranes: relevance to the molecular basis for its non-cell-selective activity.

Ziv Oren;Jeffrey C. Lerman;Gudmundur H. Gudmundsson;Birgitta Agerberth.
Biochemical Journal (1999)

703 Citations

Host defense peptides as new weapons in cancer treatment.

N Papo;Y Shai.
Cellular and Molecular Life Sciences (2005)

567 Citations

Ultrashort antibacterial and antifungal lipopeptides

Arik Makovitzki;Dorit Avrahami;Yechiel Shai.
Proceedings of the National Academy of Sciences of the United States of America (2006)

510 Citations

Selective lysis of bacteria but not mammalian cells by diastereomers of melittin: structure-function study

Ziv Oren;Yechiel Shai.
Biochemistry (1997)

489 Citations

Endotoxin (Lipopolysaccharide) Neutralization by Innate Immunity Host-Defense Peptides PEPTIDE PROPERTIES AND PLAUSIBLE MODES OF ACTION

Yosef Rosenfeld;Niv Papo;Yechiel Shai.
Journal of Biological Chemistry (2006)

473 Citations

Interaction of the mammalian antibacterial peptide cecropin P1 with phospholipid vesicles.

Ehud Gazit;Anita Boman;Hans G. Boman;Yechiel Shai.
Biochemistry (1995)

425 Citations

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