World's Best Scientists 2026 revealed!
Hans-Georg Sahl

Hans-Georg Sahl

Award Badge
Biology and Biochemistry
Germany
2023

D-Index & Metrics

Biology and Biochemistry

D-Index
97
Citations
39473
World Ranking
1734
National Ranking
115

Research.com Recognitions

  • 2023 - Research.com Biology and Biochemistry in Germany Leader Award

Overview

Hans-Georg Sahl is affiliated with the University of Bonn in Germany. Their research spans multiple fields of study, primarily focused on Medicine and Biochemistry, Genetics and Molecular Biology. The work engages with a range of subfields including Molecular Biology, Pharmacology, Infectious Diseases, Microbiology, and Oncology.

The main topics covered in Hans-Georg Sahl's research include:

  • Microbial Natural Products and Biosynthesis
  • Biochemical and Structural Characterization
  • Antimicrobial Resistance in Staphylococcus
  • Antimicrobial Peptides and Activities
  • Peptidase Inhibition and Analysis
  • Bacteriophages and microbial interactions
  • RNA Interference and Gene Delivery

The scientist has contributed to the following papers:

  • New developments in RiPP discovery, enzymology and engineering, 2020, Natural Product Reports
  • Ca2+-Daptomycin targets cell wall biosynthesis by forming a tripartite complex with undecaprenyl-coupled intermediates and membrane lipids, 2020, Nature Communications
  • Opposing Effects of PhoPQ and PmrAB on the Properties of Salmonella enterica serovar Typhimurium: Implications on Resistance to Antimicrobial Peptides, 2021, Biochemistry
  • Staphylococcus epidermidis bacteriocin A37 kills natural competitors with a unique mechanism of action, 2024, The ISME Journal
  • Cervimycin-Resistant Staphylococcus aureus Strains Display Vancomycin-Intermediate Resistant Phenotypes, 2022, Microbiology Spectrum

The research has been published often in the following venues:

  • Natural Product Reports
  • Nature Communications
  • Biochemistry
  • The ISME Journal
  • Microbiology Spectrum

Frequent co-authors include:

  • Fabian Grein
  • Ulrich Kubitscheck
  • Tanja Schneider
  • Ursula Steffens
  • Boris Maček

Best Publications

  • Antimicrobial and host-defense peptides as new anti-infective therapeutic strategies.

    Robert E W Hancock;Hans-Georg Sahl

  • Ribosomally synthesized and post-translationally modified peptide natural products: Overview and recommendations for a universal nomenclature

    Paul G. Arnison;Mervyn J. Bibb;Gabriele Bierbaum;Albert Alexander Bowers

  • The co-evolution of host cationic antimicrobial peptides and microbial resistance

    Andreas Peschel;Hans-Georg Sahl

  • Use of the cell wall precursor lipid II by a pore-forming peptide antibiotic

    E. Breukink;I. Wiedemann;C. van Kraaij;O. P. Kuipers

  • Insights into the Mode of Action of Chitosan as an Antibacterial Compound

    Dina Raafat;Kristine von Bargen;Albert Haas;Hans-Georg Sahl

  • Chitosan and its antimicrobial potential – a critical literature survey

    Dina Raafat;Hans-Georg Sahl

  • Specific binding of nisin to the peptidoglycan precursor lipid II combines pore formation and inhibition of cell wall biosynthesis for potent antibiotic activity

    Wiedemann;E Breukink;C van Kraaij;Oscar Kuipers

  • New developments in RiPP discovery, enzymology and engineering

    Manuel Montalbán-López;Thomas A Scott;Sangeetha Ramesh;Imran R Rahman

  • Lantibiotics: Mode of Action, Biosynthesis and Bioengineering

    G. Bierbaum;H.-G. Sahl

  • Lantibiotics: biosynthesis and biological activities of uniquely modified peptides from gram-positive bacteria.

    Hans-Georg Sahl;Gabriele Bierbaum

  • Plectasin, a Fungal Defensin, Targets the Bacterial Cell Wall Precursor Lipid II

    Tanja Schneider;Thomas Kruse;Reinhard Wimmer;Imke Wiedemann

  • Matrix-Assisted Laser Desorption Ionization-Time of Flight Mass Spectrometry for Fast and Reliable Identification of Clinical Yeast Isolates

    G. Marklein;M. Josten;U. Klanke;E. Müller

  • Dysregulation of bacterial proteolytic machinery by a new class of antibiotics

    Heike Brötz-Oesterhelt;Dieter Beyer;Hein-Peter Kroll;Rainer Endermann

  • Role of lipid-bound peptidoglycan precursors in the formation of pores by nisin, epidermin and other lantibiotics.

    Heike Brötz;Michaele Josten;Imke Wiedemann;Ursula Schneider

  • The Lantibiotic Mersacidin Inhibits Peptidoglycan Synthesis by Targeting Lipid II

    Heike Brötz;Gabriele Bierbaum;Klaus Leopold;Peter E. Reynolds

  • Mode of action of the peptide antibiotic nisin and influence on the membrane potential of whole cells and on cytoplasmic and artificial membrane vesicles

    E Ruhr;H G Sahl

  • Biosynthesis and Biological Activities of Lantibiotics with Unique Post-Translational Modifications

    Hans-Georg Sahl;Ralph W. Jack;Gabriele Bierbaum

  • Failures in Clinical Treatment of Staphylococcus aureus Infection with Daptomycin Are Associated with Alterations in Surface Charge, Membrane Phospholipid Asymmetry, and Drug Binding

    Tiffanny Jones;Michael R. Yeaman;Michael R. Yeaman;Michael R. Yeaman;George Sakoulas;Soo-Jin Yang

  • Mode of action of modified and unmodified bacteriocins from Gram-positive bacteria

    Yann Héchard;Hans Georg Sahl

  • Daptomycin inhibits cell envelope synthesis by interfering with fluid membrane microdomains

    Anna Müller;Michaela Wenzel;Henrik Strahl;Fabian Grein

Frequent Co-Authors

Gabriele Bierbaum
Gabriele Bierbaum University Hospital Bonn
Günther Jung
Günther Jung University of Tübingen
Alessandro Tossi
Alessandro Tossi University of Trieste
Arnold S. Bayer
Arnold S. Bayer University of California, Los Angeles
Yechiel Shai
Yechiel Shai Weizmann Institute of Science
Stefano Donadio
Stefano Donadio University of Wisconsin–Madison
Oscar P. Kuipers
Oscar P. Kuipers University of Groningen
Richard A. Proctor
Richard A. Proctor University of Wisconsin–Madison
John R. Tagg
John R. Tagg University of Otago
Jörn Piel
Jörn Piel ETH Zurich

If you think any of the details on this page are incorrect, let us know.

Report an issue

We appreciate your kind effort to assist us to improve this page, it would be helpful providing us with as much detail as possible in the text box below:

Best Scientists Citing Hans-Georg Sahl

Trending Scientists