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William C. Wimley

William C. Wimley

D-Index & Metrics

Biology and Biochemistry

D-Index
61
Citations
19520
World Ranking
11141
National Ranking
4823

Overview

William C. Wimley is affiliated with Tulane University in the United States. Their research spans multiple areas within biochemistry, genetics, molecular biology, immunology, and microbiology. The main fields of study encompass Biochemistry, Genetics and Molecular Biology and Immunology and Microbiology, with significant contributions in the subfields of Molecular Biology, Microbiology, Biomaterials, Epidemiology, and Immunology.

Their work addresses several scientific topics including Antimicrobial Peptides and Activities, Lipid Membrane Structure and Behavior, RNA Interference and Gene Delivery, Biochemical and Structural Characterization, Supramolecular Self-Assembly in Materials, Chemical Synthesis and Analysis, and Axon Guidance and Neuronal Signaling.

William C. Wimley has published extensively in various academic venues. The frequent publication outlets include:

  • Biophysical Journal
  • bioRxiv (Cold Spring Harbor Laboratory)
  • The Journal of Membrane Biology
  • PLoS ONE
  • Journal of Biological Chemistry

Frequent co-authors in their research collaborations consist of:

  • Kalina Hristova
  • Jenisha Ghimire
  • Shantanu Guha
  • Lisa A. Morici
  • Leisheng Sun

Their notable recent papers include:

  • "Synthetic molecular evolution of host cell-compatible, antimicrobial peptides effective against drug-resistant, biofilm-forming bacteria" (2020), published in Proceedings of the National Academy of Sciences
  • "Burkholderia thailandensis outer membrane vesicles exert antimicrobial activity against drug-resistant and competitor microbial species" (2020), published in The Journal of Microbiology
  • "Inhibition of Streptococcus mutans biofilms with bacterial-derived outer membrane vesicles" (2021), published in BMC Microbiology
  • "Crotonylation at serine 46 impairs p53 activity" (2020), published in Biochemical and Biophysical Research Communications
  • "Extracellular Vesicle Release Promotes Viral Replication during Persistent HCV Infection" (2021), published in Cells

Best Publications

  • MEMBRANE PROTEIN FOLDING AND STABILITY: Physical Principles

    Stephen H. White;William C. Wimley

  • Experimentally determined hydrophobicity scale for proteins at membrane interfaces.

    William C. Wimley;Stephen H. White

  • The Preference of Tryptophan for Membrane Interfaces

    Wai-Ming Yau;William C. Wimley;Klaus Gawrisch;Stephen H. White

  • Describing the mechanism of antimicrobial peptide action with the interfacial activity model.

    William C. Wimley

  • Solvation Energies of Amino Acid Side Chains and Backbone in a Family of Host−Guest Pentapeptides

    William C. Wimley;Trevor P Creamer;Stephen H. White

  • Hydrophobic interactions of peptides with membrane interfaces.

    Stephen H White;William C Wimley

  • The versatile β-barrel membrane protein

    William C Wimley

  • Antimicrobial Peptides: Successes, Challenges and Unanswered Questions

    William C. Wimley;Kalina Hristova

  • Structure, function, and membrane integration of defensins

    Stephen H White;William C Wimley;Michael E Selsted

  • Interactions between human defensins and lipid bilayers: evidence for formation of multimeric pores.

    William C. Wimley;Michael E. Selsted;Stephen H. White

  • Protein Folding in Membranes: Determining Energetics of Peptide-Bilayer Interactions.

    Stephen H. White;William C. Wimley;Alexey S. Ladokhin;Kalina Hristova

  • Mechanism Matters: A Taxonomy of Cell Penetrating Peptides

    W. Berkeley Kauffman;Taylor Fuselier;Jing He;William C. Wimley

  • Broad-spectrum antimicrobial peptides by rational combinatorial design and high-throughput screening: the importance of interfacial activity.

    Ramesh Rathinakumar;William F. Walkenhorst;William C. Wimley

  • Toward genomic identification of β-barrel membrane proteins: Composition and architecture of known structures

    William C. Wimley

  • Membrane partitioning: Distinguishing bilayer effects from the hydrophobic effect

    William C. Wimley;Stephen H. White

  • States of aggregation and phase transformations in mixtures of phosphatidylcholine and octyl glucoside.

    S. Almog;B. J. Litman;W. Wimley;J. Cohen

  • The ERBB4/HER4 Intracellular Domain 4ICD Is a BH3-Only Protein Promoting Apoptosis of Breast Cancer Cells

    Anjali Naresh;Weiwen Long;Gregory A. Vidal;William C. Wimley

  • Spontaneous Membrane-Translocating Peptides by Orthogonal High-throughput Screening

    Jessica R. Marks;Jesse Placone;Kalina Hristova;William C. Wimley

  • Folding of beta-sheet membrane proteins: a hydrophobic hexapeptide model.

    William C. Wimley;Kalina Hristova;Alexey S. Ladokhin;Loraine Silvestro

  • An amphipathic alpha-helix at a membrane interface: a structural study using a novel X-ray diffraction method.

    Kalina Hristova;William C. Wimley;Vinod K. Mishra;G.M. Anantharamiah

Frequent Co-Authors

Kalina Hristova
Kalina Hristova Johns Hopkins University
Stephen H. White
Stephen H. White University of California, Irvine
Robert F. Garry
Robert F. Garry Tulane University
Peter C. Searson
Peter C. Searson Johns Hopkins University
Thomas E. Thompson
Thomas E. Thompson University of Virginia
Erik K. Flemington
Erik K. Flemington Tulane University
Michael E. Selsted
Michael E. Selsted University of Southern California
Pardis C. Sabeti
Pardis C. Sabeti Harvard University
Klaus Gawrisch
Klaus Gawrisch National Institutes of Health
Ulf Göransson
Ulf Göransson Uppsala University

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